STRINGSTRING
recql4 recql4 LOC106564697 LOC106564697 LOC106562352 LOC106562352 LOC106608852 LOC106608852 LOC106609235 LOC106609235 LOC106567810 LOC106567810 LOC106610674 LOC106610674 LOC106604099 LOC106604099 LOC106576767 LOC106576767 DNA2 DNA2 LOC106574230 LOC106574230 zbtb48 zbtb48 lrwd1 lrwd1 dclre1b dclre1b smc5 smc5 ENSSSAP00000065491 ENSSSAP00000065491 LOC106607347 LOC106607347 tert tert LOC106578785 LOC106578785 LOC106573465 LOC106573465 LOC106605998 LOC106605998 ENSSSAP00000050388 ENSSSAP00000050388 LOC106609430 LOC106609430 ENSSSAP00000048317 ENSSSAP00000048317 LOC106605995 LOC106605995 LOC106571043 LOC106571043 znf827 znf827 terf1 terf1 LOC106603335 LOC106603335 wrn wrn ten1 ten1 ENSSSAP00000029344 ENSSSAP00000029344 LOC106565759 LOC106565759 LOC106612325 LOC106612325 LOC106577797 LOC106577797 LOC106601110 LOC106601110 rnf8 rnf8 ENSSSAP00000029663 ENSSSAP00000029663 LOC106589957 LOC106589957 sirt6 sirt6 pot1 pot1 LOC106582871 LOC106582871 ENSSSAP00000120874 ENSSSAP00000120874 LOC106572758 LOC106572758 LOC106610196 LOC106610196 LOC106610206 LOC106610206 LOC106610221 LOC106610221 LOC106572567 LOC106572567 LOC106586766 LOC106586766 LOC106561185 LOC106561185 WDSUB1 WDSUB1 ENSSSAP00000114968 ENSSSAP00000114968 LOC106582342 LOC106582342 LOC106566977 LOC106566977 ENSSSAP00000089086 ENSSSAP00000089086 LOC106586392 LOC106586392 dhx36 dhx36
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recql4ATP-dependent DNA helicase Q4. (1404 aa)
LOC106564697CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa)
LOC106562352Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (866 aa)
LOC106608852Uncharacterized protein LOC106608852. (635 aa)
LOC106609235Suppressor APC domain-containing protein 1-like. (119 aa)
LOC106567810Transcriptional regulator ATRX-like. (1697 aa)
LOC106610674Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (828 aa)
LOC106604099Transcriptional regulator ATRX-like. (1206 aa)
LOC106576767Homeobox protein OTX1 B-like. (300 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1073 aa)
LOC106574230WD repeat, SAM and U-box domain-containing protein 1-like isoform X3. (488 aa)
zbtb48Zinc finger and BTB domain-containing protein 48. (842 aa)
lrwd1Leucine-rich repeat and WD repeat-containing protein 1. (756 aa)
dclre1b5' exonuclease Apollo isoform X1. (704 aa)
smc5Structural maintenance of chromosomes protein 5 isoform X1. (1076 aa)
ENSSSAP00000065491annotation not available (982 aa)
LOC106607347Non-structural maintenance of chromosomes element 1 homolog isoform X1. (274 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1151 aa)
LOC106578785Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (454 aa)
LOC106573465Telomere repeats-binding bouquet formation protein 1-like isoform X4. (328 aa)
LOC106605998Nibrin-like. (442 aa)
ENSSSAP00000050388WD repeat, sterile alpha motif and U-box domain containing 1. (357 aa)
LOC106609430Uncharacterized protein LOC106609430. (1373 aa)
ENSSSAP00000048317annotation not available (57 aa)
LOC106605995Nibrin-like isoform X1. (635 aa)
LOC106571043Homeobox-containing protein 1-like isoform X2. (588 aa)
znf827Zinc finger protein 827. (1038 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (379 aa)
LOC106603335Transcriptional regulator ATRX-like. (1643 aa)
wrnWerner syndrome ATP-dependent helicase isoform X2. (1467 aa)
ten1CST complex subunit TEN1 isoform X2. (102 aa)
ENSSSAP00000029344annotation not available (609 aa)
LOC106565759SRSF protein kinase 3-like isoform X3. (638 aa)
LOC106612325Transcriptional regulator ATRX-like. (2621 aa)
LOC106577797Uncharacterized protein LOC106577797 isoform X2. (466 aa)
LOC106601110Non-structural maintenance of chromosomes element 1 homolog. (274 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (538 aa)
ENSSSAP00000029663annotation not available (85 aa)
LOC106589957Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (525 aa)
sirt6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (383 aa)
pot1Protection of telomeres protein 1 isoform X1. (838 aa)
LOC106582871SRSF protein kinase 3-like isoform X2. (560 aa)
ENSSSAP00000120874Structural maintenance of chromosomes 5. (734 aa)
LOC106572758SRSF protein kinase 3-like isoform X3; Belongs to the protein kinase superfamily. (412 aa)
LOC106610196Zinc finger protein 827-like. (226 aa)
LOC106610206Zinc finger protein 827-like isoform X1. (701 aa)
LOC106610221Zinc finger protein 827-like. (1151 aa)
LOC106572567Zinc finger and BTB domain-containing protein 48-like isoform X1. (823 aa)
LOC106586766CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (439 aa)
LOC106561185Uncharacterized protein LOC106561185 isoform X1. (990 aa)
WDSUB1WD repeat, SAM and U-box domain-containing protein 1-like isoform X3. (482 aa)
ENSSSAP00000114968annotation not available (273 aa)
LOC106582342Telomere-associated protein RIF1-like isoform X12. (2366 aa)
LOC106566977SRSF protein kinase 2-like; Belongs to the protein kinase superfamily. (415 aa)
ENSSSAP00000089086Telomere repeat binding bouquet formation protein 2. (211 aa)
LOC106586392Telomere-associated protein RIF1-like. (2568 aa)
dhx36ATP-dependent RNA helicase DHX36. (780 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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