30 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	LOC106608355	28S ribosomal protein S5, mitochondrial-like; Belongs to the universal ribosomal protein uS5 family. (410 aa)
	mlh1	DNA mismatch repair protein Mlh1. (729 aa)
	LOC106600009	Elongation factor 2-like. (868 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (398 aa)
	LOC106569524	Elongation factor 2-like. (881 aa)
	LOC106585666	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (405 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1560 aa)
	gfm1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (814 aa)
	gfm2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (776 aa)
	LOC106588671	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1657 aa)
	LOC106570304	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1655 aa)
	RPS16	40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (171 aa)
	rs16	40S ribosomal protein S16 isoform X1; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	galk2	N-acetylgalactosamine kinase. (474 aa)
	pms2	Mismatch repair endonuclease PMS2 isoform X1. (911 aa)
	mlh3	DNA mismatch repair protein Mlh3 isoform X2. (1207 aa)
	eftud1	Elongation factor Tu GTP-binding domain-containing protein 1. (483 aa)
	LOC106577161	28S ribosomal protein S5, mitochondrial-like. (259 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (923 aa)
	LOC106562275	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
	pms1	PMS1 protein homolog 1 isoform X2. (914 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1014 aa)
	LOC106600990	116 kDa U5 small nuclear ribonucleoprotein component. (970 aa)
	LOC106612544	Glucuronokinase 1-like isoform X1. (623 aa)
	erg19	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
	LOC106574616	28S ribosomal protein S9, mitochondrial-like. (405 aa)
	ef2	Elongation factor 2. (880 aa)
	galk1	Galactokinase isoform X1. (674 aa)
	LOC106613766	Elongation factor 2-like isoform X1. (875 aa)
	rs2	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (375 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106562275	LOC106585666	ENSSSAP00000049522	ENSSSAP00000108465	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.990
LOC106562275	erg19	ENSSSAP00000049522	ENSSSAP00000033668	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.900
LOC106562275	mvk	ENSSSAP00000049522	ENSSSAP00000116002	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.990
LOC106569524	LOC106570304	ENSSSAP00000115384	ENSSSAP00000083889	Elongation factor 2-like.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.469
LOC106569524	LOC106574616	ENSSSAP00000115384	ENSSSAP00000026823	Elongation factor 2-like.	28S ribosomal protein S9, mitochondrial-like.	0.914
LOC106569524	LOC106577161	ENSSSAP00000115384	ENSSSAP00000054869	Elongation factor 2-like.	28S ribosomal protein S5, mitochondrial-like.	0.805
LOC106569524	LOC106588671	ENSSSAP00000115384	ENSSSAP00000084345	Elongation factor 2-like.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.469
LOC106569524	LOC106608355	ENSSSAP00000115384	ENSSSAP00000099417	Elongation factor 2-like.	28S ribosomal protein S5, mitochondrial-like; Belongs to the universal ribosomal protein uS5 family.	0.805
LOC106569524	RPS16	ENSSSAP00000115384	ENSSSAP00000078966	Elongation factor 2-like.	40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.965
LOC106569524	gfm2	ENSSSAP00000115384	ENSSSAP00000087441	Elongation factor 2-like.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.423
LOC106569524	rs16	ENSSSAP00000115384	ENSSSAP00000066915	Elongation factor 2-like.	40S ribosomal protein S16 isoform X1; Belongs to the universal ribosomal protein uS9 family.	0.965
LOC106569524	rs2	ENSSSAP00000115384	ENSSSAP00000003447	Elongation factor 2-like.	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.927
LOC106569524	top2a	ENSSSAP00000115384	ENSSSAP00000092513	Elongation factor 2-like.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.469
LOC106570304	LOC106569524	ENSSSAP00000083889	ENSSSAP00000115384	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor 2-like.	0.469
LOC106570304	LOC106574616	ENSSSAP00000083889	ENSSSAP00000026823	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	28S ribosomal protein S9, mitochondrial-like.	0.524
LOC106570304	LOC106600009	ENSSSAP00000083889	ENSSSAP00000118594	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor 2-like.	0.469
LOC106570304	LOC106613766	ENSSSAP00000083889	ENSSSAP00000005375	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor 2-like isoform X1.	0.469
LOC106570304	ef2	ENSSSAP00000083889	ENSSSAP00000024296	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor 2.	0.469
LOC106570304	eftud1	ENSSSAP00000083889	ENSSSAP00000057490	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor Tu GTP-binding domain-containing protein 1.	0.477
LOC106570304	gfm2	ENSSSAP00000083889	ENSSSAP00000087441	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.685