(32 nodes) Ras guanine-nucleotide exchange factor, conserved site network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106600087	Rap guanine nucleotide exchange factor 4-like isoform X1. (999 aa)
	LOC106591265	Ras-specific guanine nucleotide-releasing factor 2-like. (1135 aa)
	SOS1	Son of sevenless homolog 1-like isoform X3. (1362 aa)
	LOC106605278	Ral guanine nucleotide dissociation stimulator-like 2 isoform X1. (740 aa)
	rapgef4	Rap guanine nucleotide exchange factor 4 isoform X3. (1026 aa)
	LOC106600822	Rap guanine nucleotide exchange factor-like 1 isoform X2. (631 aa)
	LOC106568392	ras-GEF domain-containing family member 1B-B-like. (508 aa)
	LOC106561770	ras-GEF domain-containing family member 1B-B-like. (525 aa)
	LOC106569917	Rap guanine nucleotide exchange factor 1-like isoform X1. (1258 aa)
	LOC106611443	Son of sevenless homolog 2-like. (1111 aa)
	LOC106570585	Rap guanine nucleotide exchange factor 5-like. (586 aa)
	LOC106585945	ras-GEF domain-containing family member 1B-A-like. (509 aa)
	LOC106585645	Rap guanine nucleotide exchange factor 1-like isoform X2. (1174 aa)
	sos2	Son of sevenless homolog 2. (1275 aa)
	LOC106573487	Ras-specific guanine nucleotide-releasing factor 1-like. (1260 aa)
	LOC106586233	Rap guanine nucleotide exchange factor 4-like isoform X1. (1053 aa)
	gnds	Ral guanine nucleotide dissociation stimulator-like isoform X2. (861 aa)
	rapgef1	Rap guanine nucleotide exchange factor 1 isoform X3. (1190 aa)
	LOC106572513	Rap guanine nucleotide exchange factor 3-like isoform X1. (892 aa)
	rgl1	Ral guanine nucleotide dissociation stimulator-like 1. (779 aa)
	LOC106564790	Son of sevenless homolog 1-like isoform X2. (1370 aa)
	LOC106581759	Rap guanine nucleotide exchange factor 4-like isoform X2. (998 aa)
	LOC106562868	Rap guanine nucleotide exchange factor 1-like isoform X4. (1219 aa)
	LOC106585456	Ral guanine nucleotide dissociation stimulator-like isoform X2. (843 aa)
	LOC106584386	Ral guanine nucleotide dissociation stimulator-like 1 isoform X1. (785 aa)
	LOC106581948	Ral guanine nucleotide dissociation stimulator-like 2 isoform X1. (818 aa)
	LOC106570905	ras-GEF domain-containing family member 1B-A-like isoform X1. (530 aa)
	LOC106567164	Rap guanine nucleotide exchange factor 3-like isoform X1. (906 aa)
	LOC106579966	Ral guanine nucleotide dissociation stimulator-like isoform X2. (855 aa)
	LOC106561174	Ras-specific guanine nucleotide-releasing factor 1. (1259 aa)
	LOC106561157	Ras-specific guanine nucleotide-releasing factor 2-like. (1347 aa)
	LOC106607499	Rap guanine nucleotide exchange factor-like 1 isoform X2. (621 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106561157	LOC106561174	ENSSSAP00000117027	ENSSSAP00000111753	Ras-specific guanine nucleotide-releasing factor 2-like.	Ras-specific guanine nucleotide-releasing factor 1.	0.956
LOC106561157	LOC106573487	ENSSSAP00000117027	ENSSSAP00000065278	Ras-specific guanine nucleotide-releasing factor 2-like.	Ras-specific guanine nucleotide-releasing factor 1-like.	0.956
LOC106561174	LOC106561157	ENSSSAP00000111753	ENSSSAP00000117027	Ras-specific guanine nucleotide-releasing factor 1.	Ras-specific guanine nucleotide-releasing factor 2-like.	0.956
LOC106561174	LOC106573487	ENSSSAP00000111753	ENSSSAP00000065278	Ras-specific guanine nucleotide-releasing factor 1.	Ras-specific guanine nucleotide-releasing factor 1-like.	0.900
LOC106561174	LOC106591265	ENSSSAP00000111753	ENSSSAP00000001589	Ras-specific guanine nucleotide-releasing factor 1.	Ras-specific guanine nucleotide-releasing factor 2-like.	0.577
LOC106567164	LOC106581759	ENSSSAP00000105579	ENSSSAP00000089722	Rap guanine nucleotide exchange factor 3-like isoform X1.	Rap guanine nucleotide exchange factor 4-like isoform X2.	0.651
LOC106567164	LOC106586233	ENSSSAP00000105579	ENSSSAP00000068125	Rap guanine nucleotide exchange factor 3-like isoform X1.	Rap guanine nucleotide exchange factor 4-like isoform X1.	0.649
LOC106570585	LOC106600822	ENSSSAP00000055477	ENSSSAP00000016918	Rap guanine nucleotide exchange factor 5-like.	Rap guanine nucleotide exchange factor-like 1 isoform X2.	0.537
LOC106570585	LOC106607499	ENSSSAP00000055477	ENSSSAP00000006260	Rap guanine nucleotide exchange factor 5-like.	Rap guanine nucleotide exchange factor-like 1 isoform X2.	0.537
LOC106572513	LOC106581759	ENSSSAP00000075009	ENSSSAP00000089722	Rap guanine nucleotide exchange factor 3-like isoform X1.	Rap guanine nucleotide exchange factor 4-like isoform X2.	0.650
LOC106572513	LOC106586233	ENSSSAP00000075009	ENSSSAP00000068125	Rap guanine nucleotide exchange factor 3-like isoform X1.	Rap guanine nucleotide exchange factor 4-like isoform X1.	0.649
LOC106573487	LOC106561157	ENSSSAP00000065278	ENSSSAP00000117027	Ras-specific guanine nucleotide-releasing factor 1-like.	Ras-specific guanine nucleotide-releasing factor 2-like.	0.956
LOC106573487	LOC106561174	ENSSSAP00000065278	ENSSSAP00000111753	Ras-specific guanine nucleotide-releasing factor 1-like.	Ras-specific guanine nucleotide-releasing factor 1.	0.900
LOC106573487	LOC106591265	ENSSSAP00000065278	ENSSSAP00000001589	Ras-specific guanine nucleotide-releasing factor 1-like.	Ras-specific guanine nucleotide-releasing factor 2-like.	0.577
LOC106581759	LOC106567164	ENSSSAP00000089722	ENSSSAP00000105579	Rap guanine nucleotide exchange factor 4-like isoform X2.	Rap guanine nucleotide exchange factor 3-like isoform X1.	0.651
LOC106581759	LOC106572513	ENSSSAP00000089722	ENSSSAP00000075009	Rap guanine nucleotide exchange factor 4-like isoform X2.	Rap guanine nucleotide exchange factor 3-like isoform X1.	0.650
LOC106581759	LOC106600087	ENSSSAP00000089722	ENSSSAP00000077402	Rap guanine nucleotide exchange factor 4-like isoform X2.	Rap guanine nucleotide exchange factor 4-like isoform X1.	0.517
LOC106581759	rapgef4	ENSSSAP00000089722	ENSSSAP00000012965	Rap guanine nucleotide exchange factor 4-like isoform X2.	Rap guanine nucleotide exchange factor 4 isoform X3.	0.518
LOC106586233	LOC106567164	ENSSSAP00000068125	ENSSSAP00000105579	Rap guanine nucleotide exchange factor 4-like isoform X1.	Rap guanine nucleotide exchange factor 3-like isoform X1.	0.649
LOC106586233	LOC106572513	ENSSSAP00000068125	ENSSSAP00000075009	Rap guanine nucleotide exchange factor 4-like isoform X1.	Rap guanine nucleotide exchange factor 3-like isoform X1.	0.649