STRINGSTRING
LOC106586396 LOC106586396 LOC106566997 LOC106566997 LOC106583902 LOC106583902 LOC106579999 LOC106579999 ppm1b-2 ppm1b-2 acvr2b acvr2b LOC106569196 LOC106569196 LOC106589410 LOC106589410 LOC106588693 LOC106588693 LOC106587576 LOC106587576 LOC106604740 LOC106604740 PRKD3-2 PRKD3-2 LOC106565515 LOC106565515 LOC106566505 LOC106566505 PHOSPHO1 PHOSPHO1 LOC106608109 LOC106608109 LOC106572218 LOC106572218 LOC106565669 LOC106565669 LOC106571953 LOC106571953 LOC106580686 LOC106580686 TGFBR2 TGFBR2 LOC106580962 LOC106580962 LOC106580346 LOC106580346 LOC106565836 LOC106565836 LOC106578535 LOC106578535 LOC106590284 LOC106590284 enoph enoph LOC106590364 LOC106590364 atp2a2 atp2a2 FEN1 FEN1 pptc7 pptc7 LOC106575518 LOC106575518 LOC106588647 LOC106588647 atp13a2 atp13a2 adcy5 adcy5 LOC106579675 LOC106579675 sucla2 sucla2 LOC106569164 LOC106569164 LOC106565282 LOC106565282 pgm1 pgm1 gnai2 gnai2 ppb ppb LOC106563153 LOC106563153 LOC106562227-2 LOC106562227-2 ATP11A ATP11A LOC106586327 LOC106586327 ilkap ilkap nlk nlk LOC106562384 LOC106562384 LOC106589688 LOC106589688 LOC106608070 LOC106608070 impa1 impa1 LOC106575860 LOC106575860 LOC106585265 LOC106585265 mk03 mk03 LOC106585157 LOC106585157 nt5c2 nt5c2 LOC106587214 LOC106587214 LOC106566706 LOC106566706 LOC106577245 LOC106577245 ppm1g ppm1g LOC106561348 LOC106561348 WEE1 WEE1 LOC106608969 LOC106608969 tgfr2 tgfr2 LOC106580555 LOC106580555 LOC106567250 LOC106567250 prkd1 prkd1 LOC106589035 LOC106589035 GNAT2-2 GNAT2-2 LOC106572859 LOC106572859 fan1 fan1 LOC106583193 LOC106583193 PRKD3 PRKD3 kit kit wee1-2 wee1-2 LOC106568528 LOC106568528 LOC106585469 LOC106585469 LOC106578933 LOC106578933 LOC106613069 LOC106613069 atp9b atp9b LOC106571946 LOC106571946 k6pp k6pp LOC106584299 LOC106584299 LOC106613657 LOC106613657 LOC106566714 LOC106566714 mapk7 mapk7 LOC106584132 LOC106584132 gnao1 gnao1 LOC106582759 LOC106582759 LOC106582753 LOC106582753 LOC106607258 LOC106607258 fpgs fpgs LOC106589258 LOC106589258 ppm1l-2 ppm1l-2 gss gss LOC106590221 LOC106590221 LOC106569322 LOC106569322 apex2 apex2 LOC106599285 LOC106599285 LOC106576788 LOC106576788 LOC106583035 LOC106583035 PGM1 PGM1 LOC106560843 LOC106560843 ATP9A-2 ATP9A-2 LOC106611200 LOC106611200 ppm1e ppm1e LOC106586454 LOC106586454 LOC106582410 LOC106582410 LOC106611735 LOC106611735 LOC106572792 LOC106572792 wee1 wee1 LOC106590443 LOC106590443 NDK7 NDK7 LOC106561758 LOC106561758 LOC106581270 LOC106581270 impa2 impa2 LOC106571506 LOC106571506 SUCLA2 SUCLA2 LOC106573039 LOC106573039 LOC106563477 LOC106563477 LOC106569759 LOC106569759 LOC106568328 LOC106568328 LOC100380632 LOC100380632 metk1 metk1 LOC106582566 LOC106582566 ran-2 ran-2 LOC100136506 LOC100136506 tert tert LOC106570854 LOC106570854 itpa itpa atp10b atp10b idhp idhp LOC106582376 LOC106582376 LOC106581525 LOC106581525 atp8b2 atp8b2 LOC106582660 LOC106582660 LOC106580902 LOC106580902 LOC106573473 LOC106573473 LOC106606027 LOC106606027 LOC106579281 LOC106579281 pk pk LOC106612376 LOC106612376 LOC106586335 LOC106586335 LOC106566064 LOC106566064 LOC106579514 LOC106579514 LOC106567013 LOC106567013 LOC106569209 LOC106569209 LOC106600914 LOC106600914 5ntc 5ntc LOC106563207 LOC106563207 phop1 phop1 LOC100196671 LOC100196671 thg1 thg1 LOC106578195 LOC106578195 ppm1n ppm1n LOC106563214 LOC106563214 LOC106583067 LOC106583067 LOC106565989 LOC106565989 LOC106603268 LOC106603268 ACLY-2 ACLY-2 LOC106561707 LOC106561707 mapk1 mapk1 LOC106610284 LOC106610284 LOC106610794 LOC106610794 adssl2 adssl2 LOC106610975 LOC106610975 LOC106590661 LOC106590661 LOC106598853 LOC106598853 LOC106583664 LOC106583664 ppat ppat phop2 phop2 rnaseh1 rnaseh1 atp8a1 atp8a1 LOC106573868 LOC106573868 LOC106590901 LOC106590901 LOC106605945 LOC106605945 adcy8 adcy8 LOC106566384 LOC106566384 LOC106566369 LOC106566369 LOC106613933 LOC106613933 LOC106587846 LOC106587846 hprt1 hprt1 LOC106600563 LOC106600563 LOC106568925 LOC106568925 LOC106569276 LOC106569276 KPYK KPYK LOC106605322 LOC106605322 eya1 eya1 LOC106564841 LOC106564841 LOC100380647 LOC100380647 riok3 riok3 GNAT2 GNAT2 gnai3 gnai3 LOC106579715 LOC106579715 LOC106584068 LOC106584068 LOC106575234 LOC106575234 LOC106560282 LOC106560282 LOC106564772 LOC106564772 LOC106561372 LOC106561372 LOC106572087 LOC106572087 LOC106584241 LOC106584241 mthfs mthfs rbks rbks LOC106574189 LOC106574189 LOC106584610 LOC106584610 LOC106570353 LOC106570353 LOC106564589 LOC106564589 LOC106567667 LOC106567667 pgm3 pgm3 LOC106576428 LOC106576428 LOC106607897 LOC106607897 LOC106611132 LOC106611132 kpyk kpyk ADCY2 ADCY2 ATP10D ATP10D LOC106579065 LOC106579065 LOC106576591 LOC106576591 LOC106610676 LOC106610676 MAP3K12 MAP3K12 LOC106607423 LOC106607423 dis3l2 dis3l2 LOC106611404 LOC106611404 ppm1a ppm1a LOC100286407 LOC100286407 LOC106609905 LOC106609905 LOC106560270 LOC106560270 LOC106600752 LOC106600752 adssl1 adssl1 LOC106606173 LOC106606173 ACLY ACLY ADCY1 ADCY1 LOC106600714 LOC106600714 LOC106610853 LOC106610853 LOC106565083 LOC106565083 LOC106600432 LOC106600432 LOC106566303 LOC106566303 LOC106602316 LOC106602316 LOC106598722 LOC106598722 COX2 COX2 COX1 COX1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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LOC106586396Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1192 aa)
LOC106566997ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (792 aa)
LOC106583902Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1040 aa)
LOC106579999Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (585 aa)
ppm1b-2Protein phosphatase 1B isoform X1. (431 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
LOC106569196Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa)
LOC106589410Protein phosphatase 1B-like isoform X1. (529 aa)
LOC106588693Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1123 aa)
LOC106587576Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1135 aa)
LOC106604740Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1162 aa)
PRKD3-2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (997 aa)
LOC106565515ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (863 aa)
LOC106566505Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (264 aa)
PHOSPHO1Probable phosphatase phospho1 isoform X1. (276 aa)
LOC106608109Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (300 aa)
LOC1065722185'-nucleotidase domain-containing protein 2-like. (599 aa)
LOC106565669Guanine nucleotide-binding protein G(K) subunit alpha-like. (389 aa)
LOC106571953Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (970 aa)
LOC106580686Alkaline phosphatase. (325 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (571 aa)
LOC106580962Protein phosphatase 1L-like. (367 aa)
LOC106580346S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (409 aa)
LOC106565836Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (435 aa)
LOC106578535ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (876 aa)
LOC106590284Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (516 aa)
enophEnolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (306 aa)
LOC106590364Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (505 aa)
atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1036 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
pptc7Protein phosphatase; Belongs to the PP2C family. (297 aa)
LOC106575518Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1180 aa)
LOC106588647Cytosolic purine 5'-nucleotidase-like isoform X1. (563 aa)
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1167 aa)
adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1194 aa)
LOC106579675Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (508 aa)
LOC106569164Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1162 aa)
LOC106565282Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (475 aa)
pgm1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (561 aa)
gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (367 aa)
ppbAlkaline phosphatase. (544 aa)
LOC106563153Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1039 aa)
LOC106562227-2Guanine nucleotide-binding protein G(O) subunit alpha-like. (354 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1269 aa)
LOC106586327Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (535 aa)
ilkapIntegrin-linked kinase-associated serine/threonine phosphatase 2C isoform X1. (352 aa)
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (520 aa)
LOC106562384Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1110 aa)
LOC106589688Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (531 aa)
LOC106608070Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1156 aa)
impa1Inositol-1-monophosphatase. (285 aa)
LOC106575860Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (898 aa)
LOC106585265S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (416 aa)
mk03Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
LOC106585157Phosphoglucomutase-like protein 5 isoform X1; Belongs to the phosphohexose mutase family. (672 aa)
nt5c2Cytosolic purine 5'-nucleotidase isoform X2. (599 aa)
LOC106587214Pyruvate kinase; Belongs to the pyruvate kinase family. (582 aa)
LOC106566706Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (959 aa)
LOC106577245S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (399 aa)
ppm1gProtein phosphatase 1G isoform X1. (559 aa)
LOC106561348Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
WEE1Wee1-like protein kinase. (646 aa)
LOC106608969Adenylate cyclase type 4-like. (1332 aa)
tgfr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (549 aa)
LOC106580555Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (858 aa)
LOC1065672505'-nucleotidase domain-containing protein 2-like. (605 aa)
prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (907 aa)
LOC106589035Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (667 aa)
GNAT2-2Guanine nucleotide-binding protein G(T) subunit alpha-2-like isoform X1. (352 aa)
LOC106572859Guanine nucleotide-binding protein G(K) subunit alpha-like isoform X2. (418 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1075 aa)
LOC106583193Guanine nucleotide-binding protein G(I) subunit alpha-2-like. (355 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (925 aa)
kitMast/stem cell growth factor receptor Kit isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (998 aa)
wee1-2Wee1-like protein kinase. (613 aa)
LOC106568528Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1238 aa)
LOC106585469Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
LOC106578933Protein phosphatase 1B-like isoform X1. (398 aa)
LOC106613069S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (459 aa)
atp9bPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1154 aa)
LOC106571946Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1192 aa)
k6ppATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (783 aa)
LOC106584299Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1160 aa)
LOC106613657Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1260 aa)
LOC106566714Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1207 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1132 aa)
LOC106584132Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1186 aa)
gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X2. (354 aa)
LOC106582759Guanine nucleotide-binding protein G(T) subunit alpha-like. (1031 aa)
LOC106582753Guanine nucleotide-binding protein G(I) subunit alpha-2-like. (355 aa)
LOC106607258Probable phosphatase phospho1 isoform X1. (278 aa)
fpgsFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (623 aa)
LOC106589258ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1126 aa)
ppm1l-2Protein phosphatase 1L. (369 aa)
gssGlutathione synthetase. (476 aa)
LOC106590221Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa)
LOC106569322Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1385 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (601 aa)
LOC106599285Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
LOC106576788DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (511 aa)
LOC106583035Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (461 aa)
PGM1Phosphoglucomutase-1-like; Belongs to the phosphohexose mutase family. (568 aa)
LOC106560843Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
ATP9A-2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1080 aa)
LOC106611200Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (908 aa)
ppm1eProtein phosphatase 1E. (615 aa)
LOC106586454Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (646 aa)
LOC106582410Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
LOC106611735Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1148 aa)
LOC106572792ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (855 aa)
wee1Wee1-like protein kinase. (607 aa)
LOC106590443Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1149 aa)
NDK7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (132 aa)
LOC106561758Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (972 aa)
LOC106581270Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (526 aa)
impa2Inositol-1-monophosphatase. (293 aa)
LOC106571506Protein phosphatase 1A-like. (342 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (470 aa)
LOC1065730395'-nucleotidase domain-containing protein 3-like. (591 aa)
LOC106563477Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (750 aa)
LOC106569759Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
LOC106568328Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (288 aa)
LOC1003806325'-nucleotidase domain-containing protein 2. (602 aa)
metk1S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (398 aa)
LOC106582566ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (707 aa)
ran-2GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...] (228 aa)
LOC100136506Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (526 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1151 aa)
LOC106570854Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1185 aa)
itpaInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (217 aa)
atp10bPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1223 aa)
idhpIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
LOC106582376Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (428 aa)
LOC106581525Protein phosphatase 1D-like. (583 aa)
atp8b2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1280 aa)
LOC106582660Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (964 aa)
LOC106580902Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (417 aa)
LOC106573473Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial-like isoform X2. (519 aa)
LOC106606027Magnesium transporter. (427 aa)
LOC106579281S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (410 aa)
pkPyruvate kinase; Belongs to the pyruvate kinase family. (553 aa)
LOC106612376Protein phosphatase 1A-like. (431 aa)
LOC106586335Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (426 aa)
LOC106566064Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (379 aa)
LOC106579514Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1227 aa)
LOC106567013Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
LOC106569209Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LOC106600914Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1197 aa)
5ntcCytosolic purine 5-nucleotidase. (544 aa)
LOC106563207Guanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
phop1Probable phosphatase phospho1. (279 aa)
LOC100196671Beta-enolase; Belongs to the enolase family. (455 aa)
thg1tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (299 aa)
LOC106578195Protein phosphatase 1K, mitochondrial-like. (149 aa)
ppm1nProbable protein phosphatase 1N. (465 aa)
LOC106563214Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1214 aa)
LOC106583067ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (858 aa)
LOC106565989Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
LOC106603268Protein phosphatase 1D-like isoform X2. (591 aa)
ACLY-2ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1135 aa)
LOC1065617075'-nucleotidase domain-containing protein 3-like. (577 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (366 aa)
LOC106610284Protein phosphatase 1K, mitochondrial-like. (376 aa)
LOC106610794Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (899 aa)
adssl2Adenylosuccinate synthetase isozyme 1 C; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity); Belongs to the adenylosuccinate synthetase family. (474 aa)
LOC106610975Protein phosphatase 1A-like isoform X3. (420 aa)
LOC106590661Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (638 aa)
LOC106598853Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1219 aa)
LOC106583664Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (470 aa)
ppatAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa)
phop2Pyridoxal phosphate phosphatase PHOSPHO2-like. (243 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (293 aa)
atp8a1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1166 aa)
LOC106573868Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1272 aa)
LOC106590901Protein phosphatase 1F-like. (327 aa)
LOC106605945Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial-like isoform X1. (524 aa)
adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1221 aa)
LOC106566384Guanine nucleotide-binding protein G(K) subunit alpha-like. (336 aa)
LOC106566369Guanine nucleotide-binding protein G(T) subunit alpha-2-like. (352 aa)
LOC106613933Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1190 aa)
LOC106587846Fumarylacetoacetase. (186 aa)
hprt1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (227 aa)
LOC106600563Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1384 aa)
LOC106568925Protein phosphatase 1L. (362 aa)
LOC106569276DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (554 aa)
KPYKPyruvate kinase; Belongs to the pyruvate kinase family. (236 aa)
LOC106605322DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (510 aa)
eya1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (330 aa)
LOC106564841S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (404 aa)
LOC100380647Guanine nucleotide-binding protein G(I) subunit alpha-1. (382 aa)
riok3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (512 aa)
GNAT2Guanine nucleotide-binding protein G(T) subunit alpha-2-like isoform X1. (354 aa)
gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (382 aa)
LOC106579715Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (275 aa)
LOC106584068Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
LOC106575234Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (563 aa)
LOC106560282Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (575 aa)
LOC106564772Protein phosphatase; Belongs to the PP2C family. (313 aa)
LOC106561372Wee1-like protein kinase. (558 aa)
LOC106572087Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1240 aa)
LOC106584241Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1168 aa)
mthfs5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (202 aa)
rbksRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (339 aa)
LOC106574189Alkaline phosphatase. (533 aa)
LOC106584610Wee1-like protein kinase. (628 aa)
LOC106570353Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (627 aa)
LOC106564589DNA polymerase lambda-like; Belongs to the DNA polymerase type-X family. (565 aa)
LOC106567667Protein phosphatase 1E-like. (622 aa)
pgm3Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (544 aa)
LOC106576428Guanine nucleotide-binding protein G(I) subunit alpha-1-like. (437 aa)
LOC106607897Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1182 aa)
LOC106611132Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1406 aa)
kpykPyruvate kinase; Belongs to the pyruvate kinase family. (634 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1386 aa)
LOC106579065Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
LOC106576591DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (342 aa)
LOC106610676Protein phosphatase 1G-like. (530 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
LOC106607423Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1191 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1049 aa)
LOC106611404Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1057 aa)
ppm1aProtein phosphatase 1A, magnesium dependent, alpha isoform X1. (431 aa)
LOC100286407Alkaline phosphatase. (544 aa)
LOC106609905Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1090 aa)
LOC106560270Mast/stem cell growth factor receptor Kit-like isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1005 aa)
LOC106600752Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (479 aa)
adssl1Adenylosuccinate synthetase isozyme 1 B; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity); Belongs to the adenylosuccinate synthetase family. (456 aa)
LOC106606173TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (582 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1110 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1149 aa)
LOC106600714Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC106610853Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (470 aa)
LOC106565083Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1244 aa)
LOC106600432Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
LOC106566303Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1053 aa)
LOC106602316Protein phosphatase 1K, mitochondrial-like. (374 aa)
LOC106598722Protein phosphatase 1A isoform X1. (389 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (230 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (516 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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