STRINGSTRING
pold4 pold4 pold3 pold3 LOC106608852 LOC106608852 PCNA PCNA ENSSSAP00000019392 ENSSSAP00000019392 ENSSSAP00000019926 ENSSSAP00000019926 LOC106601920 LOC106601920 LOC106577797 LOC106577797 wrn wrn DPOD1 DPOD1 rfa1 rfa1 rpa2 rpa2 LOC106588659 LOC106588659 LOC106612933 LOC106612933 ENSSSAP00000065248 ENSSSAP00000065248 LOC106580445 LOC106580445 DNA2 DNA2 LOC106605109 LOC106605109 rpa3 rpa3 pot1 pot1 LOC106570310 LOC106570310 pold2 pold2 blm blm FEN1 FEN1 lig1 lig1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pold4DNA polymerase subunit delta-4. (125 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
LOC106608852Uncharacterized protein LOC106608852. (635 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000019392Proliferating cell nuclear antigen. (218 aa)
ENSSSAP00000019926annotation not available (202 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
LOC106577797Uncharacterized protein LOC106577797 isoform X2. (466 aa)
wrnWerner syndrome ATP-dependent helicase isoform X2. (1467 aa)
DPOD1DNA polymerase. (899 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rpa2Replication protein A 32 kDa subunit. (278 aa)
LOC106588659Replication protein A 32 kDa subunit-A-like isoform X1. (266 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
ENSSSAP00000065248annotation not available (188 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1073 aa)
LOC106605109Replication protein A 32 kDa subunit-like. (278 aa)
rpa3Replication protein A3. (159 aa)
pot1Protection of telomeres protein 1 isoform X1. (838 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
blmBloom syndrome protein isoform X1. (1471 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
lig1DNA ligase. (1088 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.