STRINGSTRING
LOC106576591-2 LOC106576591-2 lig1 lig1 ENSSSAP00000112721 ENSSSAP00000112721 FEN1 FEN1 pole2 pole2 LOC106575507 LOC106575507 LOC106564654 LOC106564654 ENSSSAP00000102908 ENSSSAP00000102908 pold2 pold2 LOC106570310 LOC106570310 LOC106567314 LOC106567314 dpoe4 dpoe4 ENSSSAP00000090923 ENSSSAP00000090923 rfc4 rfc4 rpa3 rpa3 LOC106605109 LOC106605109 ENSSSAP00000088520 ENSSSAP00000088520 pole pole rfc5 rfc5 pole3 pole3 ENSSSAP00000079200 ENSSSAP00000079200 apex2 apex2 rcbtb2 rcbtb2 LOC106580445 LOC106580445 ENSSSAP00000065248 ENSSSAP00000065248 LOC106612933 LOC106612933 LOC106574681 LOC106574681 LOC106588659 LOC106588659 rpa2 rpa2 apex1 apex1 rfa1 rfa1 ENSSSAP00000047854 ENSSSAP00000047854 DPOD1 DPOD1 ENSSSAP00000044108 ENSSSAP00000044108 polb polb LOC106580473 LOC106580473 ENSSSAP00000036217 ENSSSAP00000036217 LOC106606528 LOC106606528 LOC106601920 LOC106601920 ENSSSAP00000019926 ENSSSAP00000019926 ENSSSAP00000019392 ENSSSAP00000019392 PCNA PCNA LOC106613703 LOC106613703 RCBTB1 RCBTB1 LOC106576591 LOC106576591 rfc2 rfc2 meiob meiob pold3 pold3 pold4 pold4 rfc3 rfc3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC106576591-2DNA-(apurinic or apyrimidinic site) lyase-like. (342 aa)
lig1DNA ligase. (1088 aa)
ENSSSAP00000112721annotation not available (332 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (567 aa)
LOC106575507RCC1 and BTB domain-containing protein 1-like isoform X4. (700 aa)
LOC106564654ATPase family AAA domain-containing protein 5-like isoform X2. (547 aa)
ENSSSAP00000102908annotation not available (83 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
LOC106567314DNA-(Apurinic or apyrimidinic site) lyase 2-like. (299 aa)
dpoe4DNA-directed DNA polymerase epsilon 4. (130 aa)
ENSSSAP00000090923annotation not available (91 aa)
rfc4Replication factor C subunit 4 isoform X1. (361 aa)
rpa3Replication protein A3. (159 aa)
LOC106605109Replication protein A 32 kDa subunit-like. (278 aa)
ENSSSAP00000088520Replication factor C (activator 1) 5. (305 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
rfc5Replication factor C subunit 5. (341 aa)
pole3DNA-directed DNA polymerase epsilon 3. (151 aa)
ENSSSAP00000079200Replication factor C (activator 1) 2. (372 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (601 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (492 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000065248annotation not available (188 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
LOC106574681RCC1 and BTB domain-containing protein 1-like isoform X3. (631 aa)
LOC106588659Replication protein A 32 kDa subunit-A-like isoform X1. (266 aa)
rpa2Replication protein A 32 kDa subunit. (278 aa)
apex1Salmo salar APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1), mRNA. (344 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
ENSSSAP00000047854annotation not available (265 aa)
DPOD1DNA polymerase. (899 aa)
ENSSSAP00000044108annotation not available (850 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (344 aa)
LOC106580473DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (312 aa)
ENSSSAP00000036217annotation not available (352 aa)
LOC106606528ATPase family AAA domain-containing protein 5-like isoform X1. (1873 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
ENSSSAP00000019926annotation not available (202 aa)
ENSSSAP00000019392Proliferating cell nuclear antigen. (218 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC106613703DNA polymerase epsilon subunit 4-like. (149 aa)
RCBTB1RCC1 and BTB domain-containing protein 1-like isoform X1. (572 aa)
LOC106576591DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (342 aa)
rfc2Replication factor C subunit 2. (381 aa)
meiobMeiosis-specific with OB domain-containing protein isoform X1. (464 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
pold4DNA polymerase subunit delta-4. (125 aa)
rfc3Replication factor C subunit 3 isoform X1. (334 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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