STRINGSTRING
ENSSSAP00000109661 ENSSSAP00000109661 prim2 prim2 pola2 pola2 pold4 pold4 pold3 pold3 meiob meiob PCNA PCNA ENSSSAP00000019392 ENSSSAP00000019392 ENSSSAP00000019926 ENSSSAP00000019926 LOC106601920 LOC106601920 DPOD1 DPOD1 ENSSSAP00000047854 ENSSSAP00000047854 rfa1 rfa1 rpa2 rpa2 LOC106588659 LOC106588659 LOC106612933 LOC106612933 ENSSSAP00000065248 ENSSSAP00000065248 LOC106580445 LOC106580445 ENSSSAP00000075319 ENSSSAP00000075319 prim1 prim1 DNA2 DNA2 LOC106605109 LOC106605109 rpa3 rpa3 ENSSSAP00000093833 ENSSSAP00000093833 LOC106570310 LOC106570310 pold2 pold2 ENSSSAP00000102908 ENSSSAP00000102908 pola1 pola1 FEN1 FEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSSAP00000109661DNA primase subunit 2. (432 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (515 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa)
pold4DNA polymerase subunit delta-4. (125 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
meiobMeiosis-specific with OB domain-containing protein isoform X1. (464 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000019392Proliferating cell nuclear antigen. (218 aa)
ENSSSAP00000019926annotation not available (202 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
DPOD1DNA polymerase. (899 aa)
ENSSSAP00000047854annotation not available (265 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rpa2Replication protein A 32 kDa subunit. (278 aa)
LOC106588659Replication protein A 32 kDa subunit-A-like isoform X1. (266 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
ENSSSAP00000065248annotation not available (188 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000075319annotation not available (299 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (476 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1073 aa)
LOC106605109Replication protein A 32 kDa subunit-like. (278 aa)
rpa3Replication protein A3. (159 aa)
ENSSSAP00000093833annotation not available (134 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
ENSSSAP00000102908annotation not available (83 aa)
pola1DNA polymerase. (1466 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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