STRINGSTRING
rfc3 rfc3 prim2 prim2 pola2 pola2 pold4 pold4 pold3 pold3 meiob meiob rfc2 rfc2 RCBTB1 RCBTB1 PCNA PCNA ENSSSAP00000019392 ENSSSAP00000019392 ENSSSAP00000019926 ENSSSAP00000019926 ENSSSAP00000028441 ENSSSAP00000028441 LOC106601920 LOC106601920 LOC106606528 LOC106606528 ENSSSAP00000043443 ENSSSAP00000043443 ENSSSAP00000044108 ENSSSAP00000044108 DPOD1 DPOD1 ENSSSAP00000047854 ENSSSAP00000047854 PSF2 PSF2 rfa1 rfa1 rpa2 rpa2 ENSSSAP00000053571 ENSSSAP00000053571 LOC106588659 LOC106588659 LOC106574681 LOC106574681 LOC106612933 LOC106612933 ENSSSAP00000065248 ENSSSAP00000065248 LOC106580445 LOC106580445 rcbtb2 rcbtb2 ENSSSAP00000075319 ENSSSAP00000075319 prim1 prim1 ENSSSAP00000079200 ENSSSAP00000079200 DNA2 DNA2 gins1 gins1 rfc5 rfc5 ENSSSAP00000088520 ENSSSAP00000088520 LOC106605109 LOC106605109 rpa3 rpa3 rfc4 rfc4 ENSSSAP00000090923 ENSSSAP00000090923 ENSSSAP00000093833 ENSSSAP00000093833 LOC106570310 LOC106570310 ENSSSAP00000096806 ENSSSAP00000096806 gins3 gins3 pold2 pold2 ENSSSAP00000102908 ENSSSAP00000102908 LOC106564654 LOC106564654 sld5 sld5 LOC106575507 LOC106575507 ENSSSAP00000109661 ENSSSAP00000109661 pola1 pola1 FEN1 FEN1 lig1 lig1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc3Replication factor C subunit 3 isoform X1. (334 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (515 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (617 aa)
pold4DNA polymerase subunit delta-4. (125 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
meiobMeiosis-specific with OB domain-containing protein isoform X1. (464 aa)
rfc2Replication factor C subunit 2. (381 aa)
RCBTB1RCC1 and BTB domain-containing protein 1-like isoform X1. (572 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000019392Proliferating cell nuclear antigen. (218 aa)
ENSSSAP00000019926annotation not available (202 aa)
ENSSSAP00000028441annotation not available (109 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
LOC106606528ATPase family AAA domain-containing protein 5-like isoform X1. (1873 aa)
ENSSSAP00000043443annotation not available (148 aa)
ENSSSAP00000044108annotation not available (850 aa)
DPOD1DNA polymerase. (899 aa)
ENSSSAP00000047854annotation not available (265 aa)
PSF2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (145 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rpa2Replication protein A 32 kDa subunit. (278 aa)
ENSSSAP00000053571GINS complex subunit 2. (124 aa)
LOC106588659Replication protein A 32 kDa subunit-A-like isoform X1. (266 aa)
LOC106574681RCC1 and BTB domain-containing protein 1-like isoform X3. (631 aa)
LOC106612933Replication protein A 70 kDa DNA-binding subunit-like. (632 aa)
ENSSSAP00000065248annotation not available (188 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (492 aa)
ENSSSAP00000075319annotation not available (299 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (476 aa)
ENSSSAP00000079200Replication factor C (activator 1) 2. (372 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1073 aa)
gins1DNA replication complex GINS protein PSF1. (196 aa)
rfc5Replication factor C subunit 5. (341 aa)
ENSSSAP00000088520Replication factor C (activator 1) 5. (305 aa)
LOC106605109Replication protein A 32 kDa subunit-like. (278 aa)
rpa3Replication protein A3. (159 aa)
rfc4Replication factor C subunit 4 isoform X1. (361 aa)
ENSSSAP00000090923annotation not available (91 aa)
ENSSSAP00000093833annotation not available (134 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
ENSSSAP00000096806GINS complex subunit 4 (Sld5 homolog). (216 aa)
gins3DNA replication complex GINS protein PSF3. (174 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
ENSSSAP00000102908annotation not available (83 aa)
LOC106564654ATPase family AAA domain-containing protein 5-like isoform X2. (547 aa)
sld5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (222 aa)
LOC106575507RCC1 and BTB domain-containing protein 1-like isoform X4. (700 aa)
ENSSSAP00000109661DNA primase subunit 2. (432 aa)
pola1DNA polymerase. (1466 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (402 aa)
lig1DNA ligase. (1088 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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