53 items (Salmo salar) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT11	Wnt family member 11. (268 aa)
	LOC106589772	Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
	LOC106569536	F-BAR domain only protein 2-like isoform X8. (1096 aa)
	epn1	Epsin-1. (722 aa)
	LOC106590795	Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
	LOC100136559	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	LOC106601022	Ras-related protein Rab-5C-like. (219 aa)
	LOC106608673	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
	SDF1	Stromal cell-derived factor 1 precursor; Belongs to the intercrine alpha (chemokine CxC) family. (158 aa)
	LOC106605818	Epsin-1-like. (1514 aa)
	LOC106576883	Epsin-1-like. (478 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	synj1-2	Synaptojanin-1 isoform X7. (328 aa)
	LOC106576372	Protein kinase C and casein kinase substrate in neurons protein 2-like isoform X1. (511 aa)
	LOC106596195	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (644 aa)
	LOC106607292	Ras-related protein Rab-5C-like isoform X1. (219 aa)
	LOC106587393	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (830 aa)
	LOC106562249	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (830 aa)
	ENSSSAP00000036225	Protein kinase C and casein kinase substrate in neurons 2. (493 aa)
	LOC106573848	Myc box-dependent-interacting protein 1-like. (292 aa)
	LOC106599328	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	ENSSSAP00000043851	Amphiphysin. (1216 aa)
	LOC106608297	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	hspa8	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family. (672 aa)
	LOC106613337	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	dnm1	Dynamin-1 isoform X7; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	LOC106604392	Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
	rab5c	Ras-related protein Rab-5C. (220 aa)
	LOC106612106	Transforming growth factor beta; Belongs to the TGF-beta family. (425 aa)
	LOC106578610	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	LOC106605021	Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
	LOC106580561	Protein patched homolog 1-like. (1543 aa)
	LOC106569233	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	LOC106572383	wiskott-Aldrich syndrome protein homolog. (509 aa)
	PTCH1	Protein patched homolog 1 isoform X1. (1508 aa)
	LOC106584161	Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	hsp7c	Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family. (716 aa)
	fcho2	F-BAR domain only protein 2 isoform X1. (1080 aa)
	LOC106584373	F-BAR domain only protein 1-like isoform X2. (1191 aa)
	LOC106603659	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family. (660 aa)
	LOC106567248	Wiskott-Aldrich syndrome protein homolog. (506 aa)
	LOC106613838	F-BAR domain only protein 1-like isoform X2. (1174 aa)
	LOC106603540	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	LOC106567945	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	LOC106590905	Myc box-dependent-interacting protein 1-like. (426 aa)
	LOC106585668	Transient receptor potential cation channel subfamily V member 4-like isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (874 aa)
	LOC106563563	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	CAV3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	trpv4	Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (902 aa)
	cav3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV3	CAV3-2	ENSSSAP00000017851	ENSSSAP00000115215	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3	LOC106567248	ENSSSAP00000017851	ENSSSAP00000090907	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Wiskott-Aldrich syndrome protein homolog.	0.551
CAV3	LOC106572383	ENSSSAP00000017851	ENSSSAP00000081054	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	wiskott-Aldrich syndrome protein homolog.	0.551
CAV3	cav3	ENSSSAP00000017851	ENSSSAP00000060055	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3	dnm1	ENSSSAP00000017851	ENSSSAP00000057376	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-1 isoform X7; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.701
CAV3-2	CAV3	ENSSSAP00000115215	ENSSSAP00000017851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3-2	LOC106567248	ENSSSAP00000115215	ENSSSAP00000090907	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Wiskott-Aldrich syndrome protein homolog.	0.427
CAV3-2	LOC106572383	ENSSSAP00000115215	ENSSSAP00000081054	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	wiskott-Aldrich syndrome protein homolog.	0.427
CAV3-2	cav3-2	ENSSSAP00000115215	ENSSSAP00000118569	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3-2	dnm1	ENSSSAP00000115215	ENSSSAP00000057376	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-1 isoform X7; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.595
ENSSSAP00000036225	ENSSSAP00000043851	ENSSSAP00000036225	ENSSSAP00000043851	Protein kinase C and casein kinase substrate in neurons 2.	Amphiphysin.	0.432
ENSSSAP00000036225	LOC106562249	ENSSSAP00000036225	ENSSSAP00000033788	Protein kinase C and casein kinase substrate in neurons 2.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.410
ENSSSAP00000036225	LOC106567248	ENSSSAP00000036225	ENSSSAP00000090907	Protein kinase C and casein kinase substrate in neurons 2.	Wiskott-Aldrich syndrome protein homolog.	0.402
ENSSSAP00000036225	LOC106569536	ENSSSAP00000036225	ENSSSAP00000002543	Protein kinase C and casein kinase substrate in neurons 2.	F-BAR domain only protein 2-like isoform X8.	0.649
ENSSSAP00000036225	LOC106572383	ENSSSAP00000036225	ENSSSAP00000081054	Protein kinase C and casein kinase substrate in neurons 2.	wiskott-Aldrich syndrome protein homolog.	0.402
ENSSSAP00000036225	LOC106573848	ENSSSAP00000036225	ENSSSAP00000038102	Protein kinase C and casein kinase substrate in neurons 2.	Myc box-dependent-interacting protein 1-like.	0.432
ENSSSAP00000036225	LOC106576883	ENSSSAP00000036225	ENSSSAP00000016766	Protein kinase C and casein kinase substrate in neurons 2.	Epsin-1-like.	0.428
ENSSSAP00000036225	LOC106584373	ENSSSAP00000036225	ENSSSAP00000088494	Protein kinase C and casein kinase substrate in neurons 2.	F-BAR domain only protein 1-like isoform X2.	0.651
ENSSSAP00000036225	LOC106587393	ENSSSAP00000036225	ENSSSAP00000028898	Protein kinase C and casein kinase substrate in neurons 2.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.410
ENSSSAP00000036225	LOC106590905	ENSSSAP00000036225	ENSSSAP00000102872	Protein kinase C and casein kinase substrate in neurons 2.	Myc box-dependent-interacting protein 1-like.	0.432