STRINGSTRING
tp53 tp53 LOC106608673 LOC106608673 pxdn pxdn aspn aspn LOC106565430 LOC106565430 LOC106563231 LOC106563231 LOC106572928 LOC106572928 LOC106568976 LOC106568976 alb1 alb1 LOC106570911 LOC106570911
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
LOC106608673Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
pxdnPeroxidasin homolog isoform X1. (1489 aa)
aspnAsporin. (86 aa)
LOC106565430Gelsolin-like. (763 aa)
LOC106563231Gelsolin-like isoform X2. (817 aa)
LOC106572928Peroxidasin-like. (1491 aa)
LOC106568976Gelsolin-like. (770 aa)
alb1Serum albumin 1; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. (658 aa)
LOC106570911Serum albumin 2-like. (608 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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