STRINGSTRING
GPX2 GPX2 LOC106607888 LOC106607888 LOC106608673 LOC106608673 LOC106565774 LOC106565774 PCNA PCNA ENSSSAP00000019392 ENSSSAP00000019392 LOC106596058 LOC106596058 LOC106577309 LOC106577309 rad51 rad51 GPX7 GPX7 LOC100194734 LOC100194734 gpx8 gpx8 tp53 tp53 LOC106566059 LOC106566059 LOC106580445 LOC106580445 LOC106612297 LOC106612297 bclx bclx LOC106570901 LOC106570901
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (244 aa)
LOC106607888DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
LOC106608673Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
LOC106565774Apoptosis regulator Bcl-X. (216 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ENSSSAP00000019392Proliferating cell nuclear antigen. (218 aa)
LOC106596058Glutathione peroxidase; Belongs to the glutathione peroxidase family. (134 aa)
LOC106577309Glutathione peroxidase; Belongs to the glutathione peroxidase family. (134 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
LOC100194734Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (265 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
LOC106566059Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC106612297Glutathione peroxidase; Belongs to the glutathione peroxidase family. (177 aa)
bclxApoptosis regulator Bcl-X isoform X1. (228 aa)
LOC106570901Glutathione peroxidase; Belongs to the glutathione peroxidase family. (215 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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