STRINGSTRING
CASP6 CASP6 LOC106580826 LOC106580826 LOC106561209 LOC106561209 irf-3 irf-3 mtor mtor LOC106612870 LOC106612870 atm atm traf2 traf2 LOC106581002 LOC106581002 mk13 mk13 LOC106563303 LOC106563303 LOC106576243 LOC106576243 TLR5 TLR5 LOC106604351 LOC106604351 LOC106612881 LOC106612881 LOC106600420 LOC106600420 masp1 masp1 LOC100169858 LOC100169858 LOC106587129 LOC106587129 LOC106578087 LOC106578087 LOC106561812 LOC106561812 meltf meltf TLR8 TLR8 LOC106577972 LOC106577972 LOC106612060 LOC106612060 LOC100136459 LOC100136459 LOC106602722 LOC106602722 LOC106612055 LOC106612055 il11 il11 tlr3 tlr3 ENSSSAP00000032727 ENSSSAP00000032727 ENSSSAP00000032713 ENSSSAP00000032713 LOC106611443 LOC106611443 LOC106567263 LOC106567263 LOC106563493 LOC106563493 lyn lyn LOC106563020 LOC106563020 blnk blnk LOC106562229 LOC106562229 LOC106576445 LOC106576445 LOC106598822-2 LOC106598822-2 trp-ii trp-ii mp2k2 mp2k2 plcg1 plcg1 LOC106573447 LOC106573447 plcg2 plcg2 LOC106575321 LOC106575321 LOC106609646 LOC106609646 LOC106606711 LOC106606711 grb2-2 grb2-2 LOC106563533 LOC106563533 sal sal tab1 tab1 bpi bpi LOC106561402 LOC106561402 bcl10 bcl10 LOC106608673 LOC106608673 LOC106599750 LOC106599750 LOC106601909 LOC106601909 LOC106576553 LOC106576553 lck lck RASGRP1 RASGRP1 LOC106600963 LOC106600963 SOS1 SOS1 LOC106590780 LOC106590780 grb2 grb2 ENSSSAP00000000311 ENSSSAP00000000311 LOC106602034 LOC106602034 tp53 tp53 endog endog bi1 bi1 LOC106565422 LOC106565422 LOC106581078 LOC106581078 LOC106605635 LOC106605635 LOC106606839 LOC106606839 LOC106586883 LOC106586883 LOC106609566 LOC106609566 pak3 pak3 hsp10 hsp10 LOC106587422 LOC106587422 LOC106565101 LOC106565101 LOC106583271 LOC106583271 LOC106600441 LOC106600441 faim2 faim2 csf1 csf1 LOC106565723 LOC106565723 LOC106566295 LOC106566295 LOC106569535 LOC106569535 LOC106569146 LOC106569146 casp3 casp3 LOC106565354 LOC106565354 LOC106561969 LOC106561969 BCL2 BCL2 LOC106577010 LOC106577010 MAPK11 MAPK11 habp2 habp2 tlr13 tlr13 LOC106583122 LOC106583122 LOC106567744 LOC106567744 c9 c9 bpifb2 bpifb2 LOC106573286 LOC106573286 tlr9 tlr9 cd3e cd3e LOC106603152 LOC106603152 syk syk irf7 irf7 tnr6 tnr6 LOC106602581 LOC106602581 TAB2 TAB2 LOC106567147 LOC106567147 LOC106569986 LOC106569986 casp9 casp9 LOC106569306 LOC106569306 p38b p38b egf egf LOC106585142 LOC106585142 LOC106582467 LOC106582467 irf5 irf5 LOC106586251 LOC106586251 LOC106564790 LOC106564790 LOC106607744 LOC106607744 casp7 casp7 LOC106587252 LOC106587252 il18 il18 fyn fyn ENSSSAP00000082379 ENSSSAP00000082379 LOC106582462 LOC106582462 p38a p38a LOC100380677 LOC100380677 myd88 myd88 ptprc ptprc prkacb prkacb LOC106600975 LOC106600975 LOC106567123 LOC106567123 btk btk LOC106595495 LOC106595495 lck-2 lck-2 ENSSSAP00000071803 ENSSSAP00000071803 LOC106572399 LOC106572399 cd40l cd40l irak4 irak4 LOC106597357 LOC106597357 traf3 traf3 LOC106576553-2 LOC106576553-2 prkcq prkcq LOC106581595 LOC106581595 LOC106565619 LOC106565619 pdk1 pdk1 sos2 sos2 TLR-2 TLR-2 LOC106587464 LOC106587464 LOC106609132 LOC106609132 LOC106566344 LOC106566344 LOC106569254 LOC106569254 LOC106595673 LOC106595673 LOC106573126 LOC106573126 LOC106576952 LOC106576952 LOC106584543 LOC106584543
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP6Caspase-6-like isoform X1; Belongs to the peptidase C14A family. (321 aa)
LOC106580826Complement C2-like; Belongs to the peptidase S1 family. (808 aa)
LOC106561209Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (708 aa)
irf-3Interferon regulatory factor 3 isoform X1. (482 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2569 aa)
LOC106612870Complement C4-like. (1719 aa)
atmNon-specific serine/threonine protein kinase. (3172 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa)
LOC106581002Complement C4-B-like. (1739 aa)
mk13Mitogen-activated protein kinase. (360 aa)
LOC106563303TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (526 aa)
LOC106576243Mitogen-activated protein kinase. (364 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (658 aa)
LOC106604351Tyrosine-protein kinase. (393 aa)
LOC106612881Non-specific serine/threonine protein kinase. (561 aa)
LOC106600420B-cell lymphoma/leukemia 10-like. (267 aa)
masp1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (738 aa)
LOC100169858Toll-interacting protein-like. (278 aa)
LOC106587129FAS-associated death domain protein-like. (221 aa)
LOC106578087Bcl2-associated agonist of cell death-like. (158 aa)
LOC106561812Tetraspanin. (239 aa)
meltfSerotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate. (749 aa)
TLR8TLR8-like precursor; Belongs to the Toll-like receptor family. (1035 aa)
LOC106577972Mannose-binding protein C-like. (250 aa)
LOC106612060Tyrosine-protein kinase. (254 aa)
LOC100136459Caspase 8-like protein. (499 aa)
LOC106602722Caspase-3-like; Belongs to the peptidase C14A family. (284 aa)
LOC106612055Tyrosine-protein kinase. (578 aa)
il11Interleukin-11 isoform X1. (247 aa)
tlr3Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family. (913 aa)
ENSSSAP00000032727Complement component 4. (111 aa)
ENSSSAP00000032713Mannose-binding protein C-like. (294 aa)
LOC106611443Son of sevenless homolog 2-like. (1111 aa)
LOC106567263Cell division control protein 42 homolog isoform X2. (191 aa)
LOC106563493Bcl2-associated agonist of cell death-like. (147 aa)
lynTyrosine-protein kinase. (515 aa)
LOC106563020TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (596 aa)
blnkB-cell linker protein. (487 aa)
LOC106562229Tumor necrosis factor receptor type 1-associated DEATH domain protein-like. (299 aa)
LOC106576445Apoptotic protease-activating factor 1-like isoform X1. (1274 aa)
LOC106598822-2Haptoglobin-like isoform X2. (303 aa)
trp-iiTrypsin-2; Belongs to the peptidase S1 family. (295 aa)
mp2k2Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (403 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1327 aa)
LOC106573447Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (713 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1260 aa)
LOC106575321Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (447 aa)
LOC106609646Hepatocyte growth factor-like isoform X2. (380 aa)
LOC106606711Ras guanyl-releasing protein 3-like isoform X1. (701 aa)
grb2-2Growth factor receptor-bound protein 2. (223 aa)
LOC106563533Tetraspanin. (241 aa)
salRhamnose-binding lectin precursor. (218 aa)
tab1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (55 aa)
bpiBactericidal permeability-increasing protein precursor. (485 aa)
LOC106561402Mitogen-activated protein kinase. (385 aa)
bcl10B-cell lymphoma/leukemia 10. (226 aa)
LOC106608673Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
LOC106599750cAMP-dependent protein kinase catalytic subunit beta-like isoform X2; Belongs to the protein kinase superfamily. (422 aa)
LOC106601909Mannose-binding protein C-like. (240 aa)
LOC106576553Cell division control protein 42 homolog. (191 aa)
lckTyrosine-protein kinase. (509 aa)
RASGRP1RAS guanyl-releasing protein 1-like. (829 aa)
LOC106600963Interferon a3-like isoform X1. (175 aa)
SOS1Son of sevenless homolog 1-like isoform X3. (1362 aa)
LOC106590780TGF-beta-activated kinase 1 and MAP3K7-binding protein 1-like. (436 aa)
grb2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
ENSSSAP00000000311CAMP-dependent protein kinase catalytic subunit alpha-like. (216 aa)
LOC106602034Mannose-binding protein C-like. (294 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
endogEndonuclease. (309 aa)
bi1Testis enhanced gene transcript Bax inhibitor-1; Belongs to the BI1 family. (252 aa)
LOC106565422Guanine nucleotide exchange factor MSS4-like. (132 aa)
LOC106581078Toll/interleukin-1 receptor domain-containing adapter protein-like. (300 aa)
LOC106605635B-cell receptor CD22-like isoform X1. (415 aa)
LOC106606839cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (381 aa)
LOC106586883Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (454 aa)
LOC106609566Apoptotic protease-activating factor 1-like isoform X1. (1358 aa)
pak3Non-specific serine/threonine protein kinase. (558 aa)
hsp10Heat shock protein 10 isoform X1; Belongs to the GroES chaperonin family. (167 aa)
LOC106587422Tumor necrosis factor receptor type 1-associated DEATH domain protein. (299 aa)
LOC106565101Uncharacterized protein LOC106565101. (565 aa)
LOC106583271Probable Bax inhibitor 1 isoform X2; Belongs to the BI1 family. (314 aa)
LOC106600441Dual specificity mitogen-activated protein kinase kinase 2-like; Belongs to the protein kinase superfamily. (417 aa)
faim2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (225 aa)
csf1Macrophage colony-stimulating factor 1. (591 aa)
LOC106565723Bactericidal permeability-increasing protein-like. (475 aa)
LOC106566295Breakpoint cluster region protein-like isoform X1. (1348 aa)
LOC106569535Dual specificity mitogen-activated protein kinase kinase 2-like; Belongs to the protein kinase superfamily. (459 aa)
LOC106569146cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (370 aa)
casp3Caspase 3B; Belongs to the peptidase C14A family. (311 aa)
LOC106565354Serotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate. (743 aa)
LOC106561969FAS-associated death domain protein-like. (195 aa)
BCL2Apoptosis regulator Bcl-2-like. (230 aa)
LOC106577010Tumor necrosis factor receptor superfamily member 6-like isoform X1. (391 aa)
MAPK11Mitogen-activated protein kinase. (436 aa)
habp2Hyaluronan-binding protein 2 isoform X1. (628 aa)
tlr13Toll-like receptor 22b; Belongs to the Toll-like receptor family. (962 aa)
LOC106583122Cell division control protein 42 homolog isoform X1. (191 aa)
LOC106567744TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (595 aa)
c9Complement component C9. (610 aa)
bpifb2BPI fold-containing family B member 2. (473 aa)
LOC106573286Mitogen-activated protein kinase. (392 aa)
tlr9Toll-like receptor 9 isoform X1; Belongs to the Toll-like receptor family. (1074 aa)
cd3eCD3epsilon isoform 1 precursor. (181 aa)
LOC106603152Bcl2-associated agonist of cell death-like. (156 aa)
sykTyrosine-protein kinase. (624 aa)
irf7Interferon regulatory factor 7. (415 aa)
tnr6Tumor necrosis factor receptor superfamily member 6 precursor. (330 aa)
LOC106602581Lectin-like. (246 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2-like isoform X1. (808 aa)
LOC106567147Caspase-9-like; Belongs to the peptidase C14A family. (456 aa)
LOC106569986Cell division control protein 42 homolog. (191 aa)
casp9Caspase-9 isoform X1; Belongs to the peptidase C14A family. (450 aa)
LOC106569306B-cell lymphoma/leukemia 10-like. (262 aa)
p38bMitogen-activated protein kinase. (361 aa)
egfPro-epidermal growth factor isoform X1. (1198 aa)
LOC106585142TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (628 aa)
LOC106582467Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
irf5Interferon regulatory factor 5. (535 aa)
LOC106586251Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
LOC106564790Son of sevenless homolog 1-like isoform X2. (1370 aa)
LOC106607744TGF-beta-activated kinase 1 and MAP3K7-binding protein 2-like isoform X5. (869 aa)
casp7Caspase-7; Belongs to the peptidase C14A family. (303 aa)
LOC106587252Haptoglobin-like. (316 aa)
il18Interleukin-18. (199 aa)
fynTyrosine-protein kinase. (593 aa)
ENSSSAP00000082379Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (217 aa)
LOC106582462Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (604 aa)
p38aMitogen-activated protein kinase. (374 aa)
LOC100380677Protein-tyrosine-phosphatase. (2604 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (269 aa)
ptprcReceptor-type tyrosine-protein phosphatase C isoform X1. (1412 aa)
prkacbcAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily. (386 aa)
LOC106600975TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (1023 aa)
LOC106567123Tumor necrosis factor receptor superfamily member 5-like. (317 aa)
btkTyrosine-protein kinase. (645 aa)
LOC106595495Complement C3. (1664 aa)
lck-2Tyrosine-protein kinase. (527 aa)
ENSSSAP00000071803Interleukin-1 receptor-associated kinase 4. (334 aa)
LOC106572399Cell division control protein 42 homolog isoform X1. (191 aa)
cd40lCD40 ligand; Belongs to the tumor necrosis factor family. (264 aa)
irak4Interleukin-1 receptor-associated kinase 4. (470 aa)
LOC106597357Complement C3-like. (1648 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
LOC106576553-2Cell division control protein 42 homolog. (269 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (742 aa)
LOC106581595Haptoglobin-like. (316 aa)
LOC106565619Cell division control protein 42 homolog isoform X1. (191 aa)
pdk1Protein-serine/threonine kinase. (442 aa)
sos2Son of sevenless homolog 2. (1275 aa)
TLR-2Toll-like receptor 13. (572 aa)
LOC106587464Toll-interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity). (280 aa)
LOC106609132Interferon regulatory factor 5-like isoform X1. (481 aa)
LOC106566344Interleukin-1 receptor-associated kinase 1-like isoform X1. (752 aa)
LOC106569254Tyrosine-protein kinase. (543 aa)
LOC106595673Complement factor H-like. (668 aa)
LOC106573126Protein-tyrosine-phosphatase. (2838 aa)
LOC106576952Ras guanyl-releasing protein 3-like isoform X1. (739 aa)
LOC106584543TIR domain-containing adapter molecule 1-like. (595 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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