(39 nodes) (2017) Infectious pancreatic necrosis virus enters CHSE-214 cells via macropinocytosis. network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cav3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC106593274	Dynamin-2-like. (411 aa)
	LOC106592593	Dynamin-2-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (790 aa)
	LOC106609976	Ras-related C3 botulinum toxin substrate 1. (243 aa)
	LOC106576553	Cell division control protein 42 homolog. (191 aa)
	LOC106561555	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	LOC106601744	Ras-related C3 botulinum toxin substrate 1-like. (192 aa)
	LOC106579454	Transferrin receptor protein 1-like isoform X1. (760 aa)
	RHO	Rhodopsin. (354 aa)
	Hcls1	Hematopoietic cell-specific Lyn substrate 1. (74 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC106567263	Cell division control protein 42 homolog isoform X2. (191 aa)
	LOC106601744-2	Ras-related C3 botulinum toxin substrate 1-like. (193 aa)
	cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	LOC106573119	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (182 aa)
	LOC106612881	Non-specific serine/threonine protein kinase. (561 aa)
	LOC106597167	Transferrin receptor protein 1-like. (776 aa)
	rho	Rhodopsin. (343 aa)
	dnm2	Dynamin-2. (198 aa)
	CTTN	Src substrate cortactin-like isoform X1. (556 aa)
	dnm1	Dynamin-1 isoform X7; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	LOC106583537	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (192 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	rac1	Ras-related C3 Botulinum toxin substrate 1. (192 aa)
	LOC106565619	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC106576553-2	Cell division control protein 42 homolog. (269 aa)
	ctbp1	C-terminal-binding protein 1 isoform X2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (496 aa)
	LOC106572399	Cell division control protein 42 homolog isoform X1. (191 aa)
	HCLS1	Hematopoietic lineage cell-specific protein. (541 aa)
	trf	Serotransferrin-1; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (692 aa)
	LOC106561554	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (182 aa)
	LOC106587066	Src substrate protein p85-like isoform X2. (550 aa)
	LOC106569986	Cell division control protein 42 homolog. (191 aa)
	LOC106568779	LOW QUALITY PROTEIN: transferrin receptor protein 1-like. (407 aa)
	LOC106583122	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC100136370	Rhodopsin. (354 aa)
	CAV3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	cav2-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (192 aa)
	LOC106565578	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (184 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV3	CAV3-2	ENSSSAP00000017851	ENSSSAP00000115215	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3	LOC106561554	ENSSSAP00000017851	ENSSSAP00000093053	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.504
CAV3	LOC106561555	ENSSSAP00000017851	ENSSSAP00000008025	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.975
CAV3	LOC106565578	ENSSSAP00000017851	ENSSSAP00000118573	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.524
CAV3	LOC106565619	ENSSSAP00000017851	ENSSSAP00000065127	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog isoform X1.	0.533
CAV3	LOC106567263	ENSSSAP00000017851	ENSSSAP00000029425	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog isoform X2.	0.533
CAV3	LOC106568779	ENSSSAP00000017851	ENSSSAP00000107038	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	LOW QUALITY PROTEIN: transferrin receptor protein 1-like.	0.426
CAV3	LOC106569986	ENSSSAP00000017851	ENSSSAP00000099267	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog.	0.479
CAV3	LOC106572399	ENSSSAP00000017851	ENSSSAP00000071256	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog isoform X1.	0.533
CAV3	LOC106573119	ENSSSAP00000017851	ENSSSAP00000037600	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.504
CAV3	LOC106576553	ENSSSAP00000017851	ENSSSAP00000006793	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog.	0.479
CAV3	LOC106576553-2	ENSSSAP00000017851	ENSSSAP00000068402	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog.	0.479
CAV3	LOC106579454	ENSSSAP00000017851	ENSSSAP00000012576	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Transferrin receptor protein 1-like isoform X1.	0.426
CAV3	LOC106583122	ENSSSAP00000017851	ENSSSAP00000109877	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cell division control protein 42 homolog isoform X1.	0.533
CAV3	LOC106592593	ENSSSAP00000017851	ENSSSAP00000001504	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-2-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.612
CAV3	LOC106593274	ENSSSAP00000017851	ENSSSAP00000000320	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-2-like.	0.612
CAV3	LOC106597167	ENSSSAP00000017851	ENSSSAP00000045120	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Transferrin receptor protein 1-like.	0.426
CAV3	LOC106601744	ENSSSAP00000017851	ENSSSAP00000010307	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ras-related C3 botulinum toxin substrate 1-like.	0.610
CAV3	LOC106601744-2	ENSSSAP00000017851	ENSSSAP00000037250	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ras-related C3 botulinum toxin substrate 1-like.	0.641
CAV3	LOC106609976	ENSSSAP00000017851	ENSSSAP00000002059	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ras-related C3 botulinum toxin substrate 1.	0.610