34 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106569946	40S ribosomal protein S18 isoform X1; Belongs to the universal ribosomal protein uS13 family. (152 aa)
	LOC100136352	Actin-1. (410 aa)
	LOC106612054	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (114 aa)
	capn3	Calpain-3 isoform X1; Belongs to the peptidase C2 family. (723 aa)
	LOC106588338	Proteasome subunit beta; Belongs to the peptidase T1B family. (257 aa)
	LOC106562496	Cathepsin D-like; Belongs to the peptidase A1 family. (348 aa)
	fbxo25	F-box only protein 25 isoform X1. (365 aa)
	LOC106592547	Cathepsin D-like; Belongs to the peptidase A1 family. (410 aa)
	LOC106574199	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (431 aa)
	ENSSSAP00000019392	Proliferating cell nuclear antigen. (218 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	CAPN3	Calpain-3-like isoform X4; Belongs to the peptidase C2 family. (604 aa)
	ctsb	Cathepsin B; Belongs to the peptidase C1 family. (330 aa)
	LOC106564005	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	LOC106603941	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (139 aa)
	LOC106607447	Cathepsin D-like; Belongs to the peptidase A1 family. (424 aa)
	cav3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	CAV3-2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	myog	Myogenin. (254 aa)
	ezr	Ezrin. (619 aa)
	LOC106570911	Serum albumin 2-like. (608 aa)
	alb1	Serum albumin 1; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. (658 aa)
	cats	Cathepsin S precursor; Belongs to the peptidase C1 family. (404 aa)
	LOC106569904	Proteasome subunit beta; Belongs to the peptidase T1B family. (257 aa)
	Atg4b	ATG4 autophagy related 4 homolog B (S. cerevisiae). (306 aa)
	LOC106580445	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	LOC106584518	Cathepsin D-like; Belongs to the peptidase A1 family. (343 aa)
	myod2	Myogenic factor. (276 aa)
	LOC106567474	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	LOC106600890	Cathepsin D-like; Belongs to the peptidase A1 family. (414 aa)
	CTSS	Cathepsin S. (208 aa)
	atf4	Cyclic AMP-dependent transcription factor ATF-4. (427 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg4b	fbxo25	ENSSSAP00000080036	ENSSSAP00000030599	ATG4 autophagy related 4 homolog B (S. cerevisiae).	F-box only protein 25 isoform X1.	0.497
CAPN3	myod2	ENSSSAP00000016708	ENSSSAP00000058644	Calpain-3-like isoform X4; Belongs to the peptidase C2 family.	Myogenic factor.	0.522
CAPN3	myog	ENSSSAP00000016708	ENSSSAP00000108084	Calpain-3-like isoform X4; Belongs to the peptidase C2 family.	Myogenin.	0.455
CAV3	CAV3-2	ENSSSAP00000017851	ENSSSAP00000115215	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3	cav3	ENSSSAP00000017851	ENSSSAP00000060055	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3	myog	ENSSSAP00000017851	ENSSSAP00000108084	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myogenin.	0.529
CAV3-2	CAV3	ENSSSAP00000115215	ENSSSAP00000017851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3-2	cav3-2	ENSSSAP00000115215	ENSSSAP00000118569	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.638
CAV3-2	myog	ENSSSAP00000115215	ENSSSAP00000108084	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myogenin.	0.573
CTSS	LOC106562496	ENSSSAP00000050346	ENSSSAP00000031139	Cathepsin S.	Cathepsin D-like; Belongs to the peptidase A1 family.	0.756
CTSS	LOC106584518	ENSSSAP00000050346	ENSSSAP00000059018	Cathepsin S.	Cathepsin D-like; Belongs to the peptidase A1 family.	0.756
CTSS	LOC106592547	ENSSSAP00000050346	ENSSSAP00000030479	Cathepsin S.	Cathepsin D-like; Belongs to the peptidase A1 family.	0.756
CTSS	LOC106600890	ENSSSAP00000050346	ENSSSAP00000050369	Cathepsin S.	Cathepsin D-like; Belongs to the peptidase A1 family.	0.756
CTSS	LOC106607447	ENSSSAP00000050346	ENSSSAP00000004743	Cathepsin S.	Cathepsin D-like; Belongs to the peptidase A1 family.	0.756
CTSS	ctsb	ENSSSAP00000050346	ENSSSAP00000016617	Cathepsin S.	Cathepsin B; Belongs to the peptidase C1 family.	0.613
LOC100136352	LOC106567474	ENSSSAP00000003534	ENSSSAP00000058195	Actin-1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.411
LOC100136352	LOC106570911	ENSSSAP00000003534	ENSSSAP00000099721	Actin-1.	Serum albumin 2-like.	0.545
LOC100136352	LOC106603941	ENSSSAP00000003534	ENSSSAP00000014760	Actin-1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.411
LOC100136352	LOC106612054	ENSSSAP00000003534	ENSSSAP00000034613	Actin-1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.409
LOC100136352	alb1	ENSSSAP00000003534	ENSSSAP00000093436	Actin-1.	Serum albumin 1; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood.	0.546