(25 nodes) (2018) Identification and characterization of skin color microRNAs in Koi carp (Cyprinus carpio L.) by Illumina sequencing. network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106588324	Tyrosinase-like. (542 aa)
	MITF	Microphthalmia-associated transcription factor-like isoform X1. (527 aa)
	foxd3	Forkhead box protein D3. (364 aa)
	dkk1	Dickkopf-related protein 1 isoform X1. (294 aa)
	LOC106600426	Receptor protein-tyrosine kinase. (1250 aa)
	LOC106564005	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	SOX10	Transcription factor Sox-10-like. (492 aa)
	LOC106565743	Microphthalmia-associated transcription factor-like isoform X1. (506 aa)
	tyrp-1b	5,6-dihydroxyindole-2-carboxylic acid oxidase. (524 aa)
	sox10	Transcription factor SOX-10. (495 aa)
	LOC106601158	Transcription factor Sox-10-like. (496 aa)
	LOC100136352	Actin-1. (410 aa)
	tyrp-1	5,6-dihydroxyindole-2-carboxylic acid oxidase isoform X1. (523 aa)
	LOC106569882	Tyrosinase-like. (542 aa)
	kit	Mast/stem cell growth factor receptor Kit isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (998 aa)
	LOC106607141	Transcription factor Sox-10-like. (496 aa)
	mitf	Microphthalmia-associated transcription factor isoform X1. (514 aa)
	LOC100136546	Tyrosinase precursor. (399 aa)
	LOC106582858	Microphthalmia-associated transcription factor-like isoform X2. (412 aa)
	CEL-2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (593 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (570 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (321 aa)
	LOC106584029	Forkhead box protein D3-B-like. (366 aa)
	LOC106590362	Receptor protein-tyrosine kinase. (1193 aa)
	dkk1-2	Salmo salar Dickkopf-related protein 1 (dkk1), mRNA. (294 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEL	CEL-2	ENSSSAP00000070127	ENSSSAP00000072924	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
CEL-2	CEL	ENSSSAP00000072924	ENSSSAP00000070127	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
LOC100136546	LOC106565743	ENSSSAP00000074875	ENSSSAP00000109464	Tyrosinase precursor.	Microphthalmia-associated transcription factor-like isoform X1.	0.744
LOC100136546	LOC106569882	ENSSSAP00000074875	ENSSSAP00000090356	Tyrosinase precursor.	Tyrosinase-like.	0.901
LOC100136546	LOC106582858	ENSSSAP00000074875	ENSSSAP00000111272	Tyrosinase precursor.	Microphthalmia-associated transcription factor-like isoform X2.	0.744
LOC100136546	LOC106588324	ENSSSAP00000074875	ENSSSAP00000037832	Tyrosinase precursor.	Tyrosinase-like.	0.901
LOC100136546	LOC106601158	ENSSSAP00000074875	ENSSSAP00000001254	Tyrosinase precursor.	Transcription factor Sox-10-like.	0.622
LOC100136546	LOC106607141	ENSSSAP00000074875	ENSSSAP00000086319	Tyrosinase precursor.	Transcription factor Sox-10-like.	0.622
LOC100136546	MC1R	ENSSSAP00000074875	ENSSSAP00000049482	Tyrosinase precursor.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.	0.851
LOC100136546	MITF	ENSSSAP00000074875	ENSSSAP00000034542	Tyrosinase precursor.	Microphthalmia-associated transcription factor-like isoform X1.	0.672
LOC100136546	SOX10	ENSSSAP00000074875	ENSSSAP00000015174	Tyrosinase precursor.	Transcription factor Sox-10-like.	0.468
LOC100136546	kit	ENSSSAP00000074875	ENSSSAP00000087611	Tyrosinase precursor.	Mast/stem cell growth factor receptor Kit isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.541
LOC100136546	mitf	ENSSSAP00000074875	ENSSSAP00000076076	Tyrosinase precursor.	Microphthalmia-associated transcription factor isoform X1.	0.672
LOC100136546	sox10	ENSSSAP00000074875	ENSSSAP00000012572	Tyrosinase precursor.	Transcription factor SOX-10.	0.468
LOC106565743	LOC100136546	ENSSSAP00000109464	ENSSSAP00000074875	Microphthalmia-associated transcription factor-like isoform X1.	Tyrosinase precursor.	0.744
LOC106565743	LOC106569882	ENSSSAP00000109464	ENSSSAP00000090356	Microphthalmia-associated transcription factor-like isoform X1.	Tyrosinase-like.	0.665
LOC106565743	LOC106584029	ENSSSAP00000109464	ENSSSAP00000119112	Microphthalmia-associated transcription factor-like isoform X1.	Forkhead box protein D3-B-like.	0.763
LOC106565743	LOC106588324	ENSSSAP00000109464	ENSSSAP00000037832	Microphthalmia-associated transcription factor-like isoform X1.	Tyrosinase-like.	0.665
LOC106565743	LOC106601158	ENSSSAP00000109464	ENSSSAP00000001254	Microphthalmia-associated transcription factor-like isoform X1.	Transcription factor Sox-10-like.	0.770
LOC106565743	LOC106607141	ENSSSAP00000109464	ENSSSAP00000086319	Microphthalmia-associated transcription factor-like isoform X1.	Transcription factor Sox-10-like.	0.770