32 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100136512	Interleukin-10. (300 aa)
	LOC106564005	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	ENSSSAP00000019392	Proliferating cell nuclear antigen. (218 aa)
	LOC106596195	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (644 aa)
	aqp8	Aquaporin 8b; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
	AQP8	Aquaporin-8-like isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
	LOC100136509	Tumor necrosis factor alpha. (244 aa)
	aqp8-2	Aquaporin 8ab; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
	LOC106589558	Aquaporin-8-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	LOC106608297	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	hspa8	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family. (672 aa)
	LOC106570581	Interleukin-6 isoform A. (222 aa)
	LOC106613337	Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
	LOC106604392	Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
	LOC106612106	Transforming growth factor beta; Belongs to the TGF-beta family. (425 aa)
	LOC106580445	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	IL-10	Interleukin-10-like. (123 aa)
	LOC106605021	Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (269 aa)
	LOC106584161	Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
	LOC106563563	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	slc10a2	Ileal sodium/bile acid cotransporter. (373 aa)
	rps20	40S ribosomal protein S20. (119 aa)
	LOC106603659	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family. (660 aa)
	hsp7c	Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family. (716 aa)
	LOC100136352	Actin-1. (410 aa)
	LOC106590795	Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
	LOC100136559	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	LOC106601837	Aquaporin-8-like; Belongs to the MIP/aquaporin (TC 1.A.8) family. (288 aa)
	galt	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (371 aa)
	LOC106609622	Aquaporin-8-like isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL-10	LOC100136352	ENSSSAP00000068333	ENSSSAP00000003534	Interleukin-10-like.	Actin-1.	0.565
IL-10	LOC100136509	ENSSSAP00000068333	ENSSSAP00000041208	Interleukin-10-like.	Tumor necrosis factor alpha.	0.625
IL-10	LOC100136512	ENSSSAP00000068333	ENSSSAP00000080196	Interleukin-10-like.	Interleukin-10.	0.900
IL-10	LOC100136559	ENSSSAP00000068333	ENSSSAP00000004983	Interleukin-10-like.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.627
IL-10	LOC106563563	ENSSSAP00000068333	ENSSSAP00000109831	Interleukin-10-like.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.627
IL-10	LOC106564005	ENSSSAP00000068333	ENSSSAP00000016461	Interleukin-10-like.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.565
IL-10	LOC106570581	ENSSSAP00000068333	ENSSSAP00000053478	Interleukin-10-like.	Interleukin-6 isoform A.	0.627
IL-10	LOC106613337	ENSSSAP00000068333	ENSSSAP00000053777	Interleukin-10-like.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.628
IL-10	myd88	ENSSSAP00000068333	ENSSSAP00000080060	Interleukin-10-like.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.791
LOC100136352	IL-10	ENSSSAP00000003534	ENSSSAP00000068333	Actin-1.	Interleukin-10-like.	0.565
LOC100136352	LOC100136512	ENSSSAP00000003534	ENSSSAP00000080196	Actin-1.	Interleukin-10.	0.565
LOC100136352	LOC106596195	ENSSSAP00000003534	ENSSSAP00000022644	Actin-1.	Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family.	0.593
LOC100136352	LOC106603659	ENSSSAP00000003534	ENSSSAP00000088930	Actin-1.	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family.	0.594
LOC100136352	hsp7c	ENSSSAP00000003534	ENSSSAP00000084481	Actin-1.	Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family.	0.590
LOC100136352	hspa8	ENSSSAP00000003534	ENSSSAP00000051241	Actin-1.	Heat shock cognate 70 kDa protein; Belongs to the heat shock protein 70 family.	0.589
LOC100136352	myd88	ENSSSAP00000003534	ENSSSAP00000080060	Actin-1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.457
LOC100136352	rps20	ENSSSAP00000003534	ENSSSAP00000096620	Actin-1.	40S ribosomal protein S20.	0.495
LOC100136509	IL-10	ENSSSAP00000041208	ENSSSAP00000068333	Tumor necrosis factor alpha.	Interleukin-10-like.	0.625
LOC100136509	LOC100136512	ENSSSAP00000041208	ENSSSAP00000080196	Tumor necrosis factor alpha.	Interleukin-10.	0.625
LOC100136509	LOC106570581	ENSSSAP00000041208	ENSSSAP00000053478	Tumor necrosis factor alpha.	Interleukin-6 isoform A.	0.633