(36 nodes) (2021) The Role of Neurod Genes in Brain Development, Function, and Disease. network (Salmo salar)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAX2	Paired box 2. (133 aa)
	NEUROG1	Neurogenin-1-like. (228 aa)
	insm1	Insulinoma-associated protein 1. (472 aa)
	grp	Gastrin-releasing peptide isoform X1. (159 aa)
	myf5	Myogenic factor. (297 aa)
	LOC106578610	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	robo1	Roundabout homolog 1. (1719 aa)
	LOC106569290	Pancreas transcription factor 1 subunit alpha. (269 aa)
	LOC106569233	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	bhlhe22	Class E basic helix-loop-helix protein 22. (234 aa)
	neurod6	Neurogenic differentiation factor 6. (448 aa)
	OLIG3	Oligodendrocyte transcription factor 3-like. (249 aa)
	NEUROD2	Neurogenic differentiation factor. (359 aa)
	LOC106576326	Myogenic factor. (239 aa)
	PAX6	Paired box protein Pax-6-like isoform X5. (460 aa)
	lhx1	LIM/homeobox protein Lhx1 isoform X1. (402 aa)
	LOC106565094	Contactin-2-like. (1043 aa)
	npy	Pro-neuropeptide Y precursor. (100 aa)
	RELN	Reelin-like. (2566 aa)
	LOC106599594	Pancreas transcription factor 1 subunit alpha-like. (269 aa)
	LOC106599328	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
	LOC106590392	Class E basic helix-loop-helix protein 22-like. (250 aa)
	LOC106583505	Contactin-2-like. (1138 aa)
	LOC106584023	Low-density lipoprotein receptor-related protein 8-like isoform X1. (1009 aa)
	BHLHE22	Class E basic helix-loop-helix protein 22-like. (226 aa)
	tbr1	T-box brain protein 1. (672 aa)
	atoh1	Protein atonal homolog 1. (291 aa)
	INSM1	Insulinoma-associated protein 1a-like. (470 aa)
	olig3	Oligodendrocyte transcription factor 3. (248 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (302 aa)
	LOC106610192	Mineralocorticoid receptor-like. (1031 aa)
	stim1	Stromal interaction molecule 1 isoform X2. (809 aa)
	NEUROD2-2	Neurogenic differentiation factor. (358 aa)
	LOC106579148	Neurogenic differentiation factor 2-like. (438 aa)
	LOC106579536	Class E basic helix-loop-helix protein 22-like. (250 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BHLHE22	INSM1	ENSSSAP00000113836	ENSSSAP00000105223	Class E basic helix-loop-helix protein 22-like.	Insulinoma-associated protein 1a-like.	0.627
BHLHE22	LOC106565094	ENSSSAP00000113836	ENSSSAP00000055549	Class E basic helix-loop-helix protein 22-like.	Contactin-2-like.	0.491
BHLHE22	LOC106569290	ENSSSAP00000113836	ENSSSAP00000075548	Class E basic helix-loop-helix protein 22-like.	Pancreas transcription factor 1 subunit alpha.	0.611
BHLHE22	LOC106583505	ENSSSAP00000113836	ENSSSAP00000118144	Class E basic helix-loop-helix protein 22-like.	Contactin-2-like.	0.491
BHLHE22	LOC106584023	ENSSSAP00000113836	ENSSSAP00000114467	Class E basic helix-loop-helix protein 22-like.	Low-density lipoprotein receptor-related protein 8-like isoform X1.	0.402
BHLHE22	LOC106599594	ENSSSAP00000113836	ENSSSAP00000038718	Class E basic helix-loop-helix protein 22-like.	Pancreas transcription factor 1 subunit alpha-like.	0.611
BHLHE22	PAX2	ENSSSAP00000113836	ENSSSAP00000022373	Class E basic helix-loop-helix protein 22-like.	Paired box 2.	0.407
BHLHE22	PAX6	ENSSSAP00000113836	ENSSSAP00000017493	Class E basic helix-loop-helix protein 22-like.	Paired box protein Pax-6-like isoform X5.	0.508
BHLHE22	insm1	ENSSSAP00000113836	ENSSSAP00000063563	Class E basic helix-loop-helix protein 22-like.	Insulinoma-associated protein 1.	0.627
BHLHE22	lhx1	ENSSSAP00000113836	ENSSSAP00000020430	Class E basic helix-loop-helix protein 22-like.	LIM/homeobox protein Lhx1 isoform X1.	0.491
BHLHE22	tbr1	ENSSSAP00000113836	ENSSSAP00000112217	Class E basic helix-loop-helix protein 22-like.	T-box brain protein 1.	0.423
CDK5R1	LOC106579148	ENSSSAP00000094557	ENSSSAP00000043802	Cyclin-dependent kinase 5 activator.	Neurogenic differentiation factor 2-like.	0.593
CDK5R1	LOC106584023	ENSSSAP00000094557	ENSSSAP00000114467	Cyclin-dependent kinase 5 activator.	Low-density lipoprotein receptor-related protein 8-like isoform X1.	0.623
CDK5R1	NEUROD2	ENSSSAP00000094557	ENSSSAP00000003770	Cyclin-dependent kinase 5 activator.	Neurogenic differentiation factor.	0.593
CDK5R1	NEUROD2-2	ENSSSAP00000094557	ENSSSAP00000042762	Cyclin-dependent kinase 5 activator.	Neurogenic differentiation factor.	0.593
CDK5R1	NEUROG1	ENSSSAP00000094557	ENSSSAP00000062610	Cyclin-dependent kinase 5 activator.	Neurogenin-1-like.	0.592
INSM1	BHLHE22	ENSSSAP00000105223	ENSSSAP00000113836	Insulinoma-associated protein 1a-like.	Class E basic helix-loop-helix protein 22-like.	0.627
INSM1	LOC106565094	ENSSSAP00000105223	ENSSSAP00000055549	Insulinoma-associated protein 1a-like.	Contactin-2-like.	0.497
INSM1	LOC106569290	ENSSSAP00000105223	ENSSSAP00000075548	Insulinoma-associated protein 1a-like.	Pancreas transcription factor 1 subunit alpha.	0.543
INSM1	LOC106579148	ENSSSAP00000105223	ENSSSAP00000043802	Insulinoma-associated protein 1a-like.	Neurogenic differentiation factor 2-like.	0.578