5 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106608430	Toll-like receptor 2. (1420 aa)
	LOC106580799	Toll-like receptor 2 type-2. (898 aa)
	LOC106605325	Toll-like receptor 2 type-1. (884 aa)
	IL-10	Interleukin-10-like. (123 aa)
	LOC100136512	Interleukin-10. (300 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL-10	LOC100136512	ENSSSAP00000068333	ENSSSAP00000080196	Interleukin-10-like.	Interleukin-10.	0.900
IL-10	LOC106580799	ENSSSAP00000068333	ENSSSAP00000090785	Interleukin-10-like.	Toll-like receptor 2 type-2.	0.463
IL-10	LOC106605325	ENSSSAP00000068333	ENSSSAP00000021105	Interleukin-10-like.	Toll-like receptor 2 type-1.	0.462
IL-10	LOC106608430	ENSSSAP00000068333	ENSSSAP00000007789	Interleukin-10-like.	Toll-like receptor 2.	0.665
LOC100136512	IL-10	ENSSSAP00000080196	ENSSSAP00000068333	Interleukin-10.	Interleukin-10-like.	0.900
LOC100136512	LOC106580799	ENSSSAP00000080196	ENSSSAP00000090785	Interleukin-10.	Toll-like receptor 2 type-2.	0.463
LOC100136512	LOC106605325	ENSSSAP00000080196	ENSSSAP00000021105	Interleukin-10.	Toll-like receptor 2 type-1.	0.462
LOC100136512	LOC106608430	ENSSSAP00000080196	ENSSSAP00000007789	Interleukin-10.	Toll-like receptor 2.	0.665
LOC106580799	IL-10	ENSSSAP00000090785	ENSSSAP00000068333	Toll-like receptor 2 type-2.	Interleukin-10-like.	0.463
LOC106580799	LOC100136512	ENSSSAP00000090785	ENSSSAP00000080196	Toll-like receptor 2 type-2.	Interleukin-10.	0.463
LOC106580799	LOC106605325	ENSSSAP00000090785	ENSSSAP00000021105	Toll-like receptor 2 type-2.	Toll-like receptor 2 type-1.	0.900
LOC106580799	LOC106608430	ENSSSAP00000090785	ENSSSAP00000007789	Toll-like receptor 2 type-2.	Toll-like receptor 2.	0.900
LOC106605325	IL-10	ENSSSAP00000021105	ENSSSAP00000068333	Toll-like receptor 2 type-1.	Interleukin-10-like.	0.462
LOC106605325	LOC100136512	ENSSSAP00000021105	ENSSSAP00000080196	Toll-like receptor 2 type-1.	Interleukin-10.	0.462
LOC106605325	LOC106580799	ENSSSAP00000021105	ENSSSAP00000090785	Toll-like receptor 2 type-1.	Toll-like receptor 2 type-2.	0.900
LOC106605325	LOC106608430	ENSSSAP00000021105	ENSSSAP00000007789	Toll-like receptor 2 type-1.	Toll-like receptor 2.	0.900
LOC106608430	IL-10	ENSSSAP00000007789	ENSSSAP00000068333	Toll-like receptor 2.	Interleukin-10-like.	0.665
LOC106608430	LOC100136512	ENSSSAP00000007789	ENSSSAP00000080196	Toll-like receptor 2.	Interleukin-10.	0.665
LOC106608430	LOC106580799	ENSSSAP00000007789	ENSSSAP00000090785	Toll-like receptor 2.	Toll-like receptor 2 type-2.	0.900
LOC106608430	LOC106605325	ENSSSAP00000007789	ENSSSAP00000021105	Toll-like receptor 2.	Toll-like receptor 2 type-1.	0.900