9 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tlr3	Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family. (913 aa)
	TLR8	TLR8-like precursor; Belongs to the Toll-like receptor family. (1035 aa)
	TLR5	Toll-like receptor 5; Belongs to the Toll-like receptor family. (658 aa)
	TLR-2	Toll-like receptor 13. (572 aa)
	IL-10	Interleukin-10-like. (123 aa)
	LOC100136512	Interleukin-10. (300 aa)
	LOC106602581	Lectin-like. (246 aa)
	tlr9	Toll-like receptor 9 isoform X1; Belongs to the Toll-like receptor family. (1074 aa)
	LOC106604777	Toll-like receptor 6. (837 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL-10	LOC100136512	ENSSSAP00000068333	ENSSSAP00000080196	Interleukin-10-like.	Interleukin-10.	0.900
IL-10	LOC106604777	ENSSSAP00000068333	ENSSSAP00000113763	Interleukin-10-like.	Toll-like receptor 6.	0.741
IL-10	TLR-2	ENSSSAP00000068333	ENSSSAP00000063294	Interleukin-10-like.	Toll-like receptor 13.	0.586
IL-10	TLR5	ENSSSAP00000068333	ENSSSAP00000041640	Interleukin-10-like.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.762
IL-10	TLR8	ENSSSAP00000068333	ENSSSAP00000035750	Interleukin-10-like.	TLR8-like precursor; Belongs to the Toll-like receptor family.	0.531
IL-10	tlr3	ENSSSAP00000068333	ENSSSAP00000032759	Interleukin-10-like.	Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family.	0.740
IL-10	tlr9	ENSSSAP00000068333	ENSSSAP00000106992	Interleukin-10-like.	Toll-like receptor 9 isoform X1; Belongs to the Toll-like receptor family.	0.641
LOC100136512	IL-10	ENSSSAP00000080196	ENSSSAP00000068333	Interleukin-10.	Interleukin-10-like.	0.900
LOC100136512	LOC106604777	ENSSSAP00000080196	ENSSSAP00000113763	Interleukin-10.	Toll-like receptor 6.	0.577
LOC100136512	TLR-2	ENSSSAP00000080196	ENSSSAP00000063294	Interleukin-10.	Toll-like receptor 13.	0.586
LOC100136512	TLR5	ENSSSAP00000080196	ENSSSAP00000041640	Interleukin-10.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.607
LOC100136512	TLR8	ENSSSAP00000080196	ENSSSAP00000035750	Interleukin-10.	TLR8-like precursor; Belongs to the Toll-like receptor family.	0.531
LOC100136512	tlr3	ENSSSAP00000080196	ENSSSAP00000032759	Interleukin-10.	Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family.	0.658
LOC100136512	tlr9	ENSSSAP00000080196	ENSSSAP00000106992	Interleukin-10.	Toll-like receptor 9 isoform X1; Belongs to the Toll-like receptor family.	0.641
LOC106604777	IL-10	ENSSSAP00000113763	ENSSSAP00000068333	Toll-like receptor 6.	Interleukin-10-like.	0.741
LOC106604777	LOC100136512	ENSSSAP00000113763	ENSSSAP00000080196	Toll-like receptor 6.	Interleukin-10.	0.577
LOC106604777	TLR-2	ENSSSAP00000113763	ENSSSAP00000063294	Toll-like receptor 6.	Toll-like receptor 13.	0.513
LOC106604777	TLR5	ENSSSAP00000113763	ENSSSAP00000041640	Toll-like receptor 6.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.871
LOC106604777	TLR8	ENSSSAP00000113763	ENSSSAP00000035750	Toll-like receptor 6.	TLR8-like precursor; Belongs to the Toll-like receptor family.	0.584
LOC106604777	tlr3	ENSSSAP00000113763	ENSSSAP00000032759	Toll-like receptor 6.	Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family.	0.562