25 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106612231	Copper-transporting ATPase 1-like. (1299 aa)
	ENSSSAP00000019392	Proliferating cell nuclear antigen. (218 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	LOC106564005	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	ccnd1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
	LOC106576326	Myogenic factor. (239 aa)
	sp1	Transcription factor Sp1 isoform X2. (674 aa)
	LOC100136352	Actin-1. (410 aa)
	ccnb1	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (401 aa)
	lox	Protein-lysine 6-oxidase isoform X1. (413 aa)
	myog	Myogenin. (254 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	LOC106605446	Mothers against decapentaplegic homolog. (565 aa)
	smad4	Mothers against decapentaplegic homolog. (510 aa)
	LOC106571301	Connective tissue growth factor-like. (346 aa)
	LOC106589042	Connective tissue growth factor-like isoform X2. (347 aa)
	ctgf	Connective tissue growth factor precursor. (346 aa)
	LOC106585370-2	Mothers against decapentaplegic homolog 2. (464 aa)
	mrf4	Myogenic regulatory factor 4. (235 aa)
	atox1-2	Copper transport protein ATOX1 isoform X1. (79 aa)
	LOC106580445	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	myf5	Myogenic factor. (297 aa)
	atox1	Copper transport protein ATOX1 isoform X2. (70 aa)
	LOC106570673	Connective tissue growth factor-like isoform X2. (347 aa)
	cp	Ceruloplasmin; Belongs to the multicopper oxidase family. (1122 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSSAP00000019392	ccnb1	ENSSSAP00000019392	ENSSSAP00000120894	Proliferating cell nuclear antigen.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.435
ENSSSAP00000019392	ccnd1	ENSSSAP00000019392	ENSSSAP00000012233	Proliferating cell nuclear antigen.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.418
LOC100136352	ccnb1	ENSSSAP00000003534	ENSSSAP00000120894	Actin-1.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.436
LOC106564005	ccnb1	ENSSSAP00000016461	ENSSSAP00000120894	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.436
LOC106576326	mrf4	ENSSSAP00000012184	ENSSSAP00000079027	Myogenic factor.	Myogenic regulatory factor 4.	0.532
LOC106576326	myog	ENSSSAP00000012184	ENSSSAP00000108084	Myogenic factor.	Myogenin.	0.642
LOC106580445	PCNA	ENSSSAP00000068146	ENSSSAP00000018360	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.900
LOC106580445	ccnb1	ENSSSAP00000068146	ENSSSAP00000120894	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.435
LOC106580445	ccnd1	ENSSSAP00000068146	ENSSSAP00000012233	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.787
LOC106585370-2	LOC106605446	ENSSSAP00000089996	ENSSSAP00000102094	Mothers against decapentaplegic homolog 2.	Mothers against decapentaplegic homolog.	0.831
LOC106585370-2	SMAD4	ENSSSAP00000089996	ENSSSAP00000104615	Mothers against decapentaplegic homolog 2.	Mothers against decapentaplegic homolog.	0.830
LOC106585370-2	smad4	ENSSSAP00000089996	ENSSSAP00000101532	Mothers against decapentaplegic homolog 2.	Mothers against decapentaplegic homolog.	0.831
LOC106585370-2	sp1	ENSSSAP00000089996	ENSSSAP00000011689	Mothers against decapentaplegic homolog 2.	Transcription factor Sp1 isoform X2.	0.866
LOC106605446	LOC106585370-2	ENSSSAP00000102094	ENSSSAP00000089996	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog 2.	0.831
LOC106605446	sp1	ENSSSAP00000102094	ENSSSAP00000011689	Mothers against decapentaplegic homolog.	Transcription factor Sp1 isoform X2.	0.813
LOC106612231	atox1	ENSSSAP00000034810	ENSSSAP00000061554	Copper-transporting ATPase 1-like.	Copper transport protein ATOX1 isoform X2.	0.978
LOC106612231	atox1-2	ENSSSAP00000034810	ENSSSAP00000076533	Copper-transporting ATPase 1-like.	Copper transport protein ATOX1 isoform X1.	0.978
LOC106612231	cp	ENSSSAP00000034810	ENSSSAP00000037761	Copper-transporting ATPase 1-like.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.534
PCNA	LOC106580445	ENSSSAP00000018360	ENSSSAP00000068146	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.900
PCNA	ccnb1	ENSSSAP00000018360	ENSSSAP00000120894	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.435