33 items (Salmo salar) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC106604510	NAD-dependent protein deacetylase sirtuin-1-like isoform X2. (713 aa)
	jak2	Tyrosine-protein kinase. (1180 aa)
	LOC106575067	Nuclear factor erythroid 2-related factor 2-like isoform X1. (611 aa)
	RHO	Rhodopsin. (354 aa)
	LOC106607056	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (271 aa)
	LOC106608673	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
	LOC106601025	Signal transducer and activator of transcription. (802 aa)
	LOC106590030	Heme oxygenase-like. (302 aa)
	casp3	Caspase 3B; Belongs to the peptidase C14A family. (311 aa)
	BCL2	Apoptosis regulator Bcl-2-like. (230 aa)
	LOC100136370	Rhodopsin. (354 aa)
	LOC106567066	Transcription factor NF-E2 45 kDa subunit-like. (503 aa)
	nf2l2	Nuclear factor erythroid 2-related factor 2. (637 aa)
	LOC106612018	Caspase-3-like; Belongs to the peptidase C14A family. (283 aa)
	LOC106601306	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (276 aa)
	nox5	NADPH oxidase 5. (834 aa)
	LOC106572584	Transcription factor NF-E2 45 kDa subunit-like. (498 aa)
	LOC106586247	Nuclear factor erythroid 2-related factor 2-like. (614 aa)
	daam1	Disheveled-associated activator of morphogenesis 1 isoform X1. (1075 aa)
	LOC106587827	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (356 aa)
	LOC106583538	Rhodopsin. (347 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
	FOXO1	Forkhead box protein O1-A-like. (725 aa)
	LOC106569944	Cyclic AMP-dependent transcription factor ATF-6 beta-like isoform X1. (703 aa)
	rho	Rhodopsin. (343 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2569 aa)
	atm	Non-specific serine/threonine protein kinase. (3172 aa)
	atf6	Cyclic AMP-dependent transcription factor ATF-6 alpha isoform X2. (632 aa)
	LOC106602722	Caspase-3-like; Belongs to the peptidase C14A family. (284 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1. (783 aa)
	CXA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (360 aa)
	LOC106590330	Heme oxygenase-like. (330 aa)
	LOC106607297	Signal transducer and activator of transcription 3-like. (808 aa)

Your Current Organism:

Salmo salar

NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	LOC106602722	ENSSSAP00000114628	ENSSSAP00000034454	Apoptosis regulator Bcl-2-like.	Caspase-3-like; Belongs to the peptidase C14A family.	0.722
BCL2	LOC106608673	ENSSSAP00000114628	ENSSSAP00000007484	Apoptosis regulator Bcl-2-like.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.888
BCL2	LOC106612018	ENSSSAP00000114628	ENSSSAP00000091757	Apoptosis regulator Bcl-2-like.	Caspase-3-like; Belongs to the peptidase C14A family.	0.698
BCL2	atm	ENSSSAP00000114628	ENSSSAP00000045237	Apoptosis regulator Bcl-2-like.	Non-specific serine/threonine protein kinase.	0.614
BCL2	casp3	ENSSSAP00000114628	ENSSSAP00000116189	Apoptosis regulator Bcl-2-like.	Caspase 3B; Belongs to the peptidase C14A family.	0.697
BCL2	tp53	ENSSSAP00000114628	ENSSSAP00000057928	Apoptosis regulator Bcl-2-like.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.888
FOXO1	LOC106587827	ENSSSAP00000057653	ENSSSAP00000064510	Forkhead box protein O1-A-like.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.691
FOXO1	LOC106601025	ENSSSAP00000057653	ENSSSAP00000007429	Forkhead box protein O1-A-like.	Signal transducer and activator of transcription.	0.914
FOXO1	LOC106604510	ENSSSAP00000057653	ENSSSAP00000004875	Forkhead box protein O1-A-like.	NAD-dependent protein deacetylase sirtuin-1-like isoform X2.	0.843
FOXO1	LOC106608673	ENSSSAP00000057653	ENSSSAP00000007484	Forkhead box protein O1-A-like.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.497
FOXO1	sirt1	ENSSSAP00000057653	ENSSSAP00000032495	Forkhead box protein O1-A-like.	NAD-dependent protein deacetylase sirtuin-1.	0.894
FOXO1	tp53	ENSSSAP00000057653	ENSSSAP00000057928	Forkhead box protein O1-A-like.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.497
LOC100136370	LOC106583538	ENSSSAP00000111426	ENSSSAP00000059830	Rhodopsin.	Rhodopsin.	0.911
LOC100136370	RHO	ENSSSAP00000111426	ENSSSAP00000013279	Rhodopsin.	Rhodopsin.	0.916
LOC106575067	LOC106590030	ENSSSAP00000014859	ENSSSAP00000001204	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Heme oxygenase-like.	0.450
LOC106575067	LOC106590330	ENSSSAP00000014859	ENSSSAP00000030069	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Heme oxygenase-like.	0.533
LOC106575067	LOC106601306	ENSSSAP00000014859	ENSSSAP00000089978	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.450
LOC106575067	LOC106607056	ENSSSAP00000014859	ENSSSAP00000012517	Nuclear factor erythroid 2-related factor 2-like isoform X1.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.450
LOC106583538	LOC100136370	ENSSSAP00000059830	ENSSSAP00000111426	Rhodopsin.	Rhodopsin.	0.911
LOC106583538	RHO	ENSSSAP00000059830	ENSSSAP00000013279	Rhodopsin.	Rhodopsin.	0.914