STRINGSTRING
LOC100136559 LOC100136559 GPX2 GPX2 LOC100136352 LOC100136352 LOC106590795 LOC106590795 LOC106608673 LOC106608673 GSK3B GSK3B LOC106564005 LOC106564005 LOC106596058 LOC106596058 GSK3B-2 GSK3B-2 GSK3B-3 GSK3B-3 LOC106609475 LOC106609475 LOC100136509 LOC100136509 LOC106577309 LOC106577309 GPX7 GPX7 LOC106608297 LOC106608297 LOC106613337 LOC106613337 LOC100194734 LOC100194734 LOC106587134 LOC106587134 gpx8 gpx8 tp53 tp53 LOC106604392 LOC106604392 LOC106566059 LOC106566059 LOC106612106 LOC106612106 IL-10 IL-10 LOC106612297 LOC106612297 LOC106605021 LOC106605021 GSK3B-4 GSK3B-4 LOC106574396 LOC106574396 LOC100136512 LOC100136512 LOC106584161 LOC106584161 LOC106570901 LOC106570901 sod2 sod2 LOC106563563 LOC106563563 pck2 pck2 LOC106561972 LOC106561972
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100136559Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (244 aa)
LOC100136352Actin-1. (410 aa)
LOC106590795Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC106608673Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
GSK3BGlycogen synthase kinase-3 beta-like; Belongs to the protein kinase superfamily. (629 aa)
LOC106564005Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
LOC106596058Glutathione peroxidase; Belongs to the glutathione peroxidase family. (134 aa)
GSK3B-2Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (443 aa)
GSK3B-3Glycogen synthase kinase-3 beta-like isoform X4; Belongs to the protein kinase superfamily. (448 aa)
LOC106609475Insulin-like growth factor I isoform X1. (211 aa)
LOC100136509Tumor necrosis factor alpha. (244 aa)
LOC106577309Glutathione peroxidase; Belongs to the glutathione peroxidase family. (134 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (184 aa)
LOC106608297Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC106613337Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
LOC100194734Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
LOC106587134Apoptosis regulator BAX-like. (204 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (265 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
LOC106604392Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
LOC106566059Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
LOC106612106Transforming growth factor beta; Belongs to the TGF-beta family. (425 aa)
IL-10Interleukin-10-like. (123 aa)
LOC106612297Glutathione peroxidase; Belongs to the glutathione peroxidase family. (177 aa)
LOC106605021Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
GSK3B-4Glycogen synthase kinase 3 beta. (443 aa)
LOC106574396Toll-like receptor 13. (931 aa)
LOC100136512Interleukin-10. (300 aa)
LOC106584161Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
LOC106570901Glutathione peroxidase; Belongs to the glutathione peroxidase family. (215 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (301 aa)
LOC106563563Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (635 aa)
LOC106561972Apoptosis regulator BAX-like. (204 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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