STRINGSTRING
rfc3 rfc3 rbx1 rbx1 CUL4B CUL4B rd23a rd23a LOC106613684 LOC106613684 pold4 pold4 pold3 pold3 rfc2 rfc2 LOC106613703 LOC106613703 Ercc3 Ercc3 PCNA PCNA gtf2h5 gtf2h5 ccnh ccnh LOC106598394 LOC106598394 LOC106601920 LOC106601920 LOC100196672 LOC100196672 mnat1 mnat1 ercc4 ercc4 gtf2h1 gtf2h1 gtf2h4 gtf2h4 DPOD1 DPOD1 RAD23B RAD23B rfa1 rfa1 rpa2 rpa2 ercc2 ercc2 LOC106612201 LOC106612201 LOC106580445 LOC106580445 xpa xpa LOC106561926 LOC106561926 pole3 pole3 xpc xpc rfc5 rfc5 LOC106604249 LOC106604249 pole pole LOC106584761 LOC106584761 LOC106605109 LOC106605109 LOC106601193-2 LOC106601193-2 rpa3 rpa3 rfc4 rfc4 dpoe4 dpoe4 ercc8 ercc8 LOC106573817 LOC106573817 LOC106570310 LOC106570310 pold2 pold2 xpa-2 xpa-2 cul4b cul4b ercc1 ercc1 gtf2h3 gtf2h3 pole2 pole2 ercc6 ercc6 lig1 lig1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfc3Replication factor C subunit 3 isoform X1. (334 aa)
rbx1RING-box protein 1; E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and arih1 collaborate in tandem to mediate ubiquitination of target proteins, arih1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes d [...] (108 aa)
CUL4Bcullin-4B-like isoform X1; Belongs to the cullin family. (899 aa)
rd23aUV excision repair protein RAD23 homolog A. (387 aa)
LOC106613684UV excision repair protein RAD23 homolog B-like. (478 aa)
pold4DNA polymerase subunit delta-4. (125 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (449 aa)
rfc2Replication factor C subunit 2. (381 aa)
LOC106613703DNA polymerase epsilon subunit 4-like. (149 aa)
Ercc3ERCC excision repair 3, TFIIH core complex helicase subunit. (100 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
gtf2h5General transcription factor IIH subunit 5. (71 aa)
ccnhcyclin-H isoform X1; Belongs to the cyclin family. (324 aa)
LOC106598394cullin-4A-like isoform X1; Belongs to the cullin family. (514 aa)
LOC106601920DNA polymerase delta catalytic subunit-like. (681 aa)
LOC100196672General transcription factor IIH subunit. (393 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (314 aa)
ercc4DNA repair endonuclease XPF. (911 aa)
gtf2h1General transcription factor IIH subunit 1. (588 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
DPOD1DNA polymerase. (899 aa)
RAD23BUV excision repair protein RAD23 homolog B-like isoform X1. (375 aa)
rfa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
rpa2Replication protein A 32 kDa subunit. (278 aa)
ercc2TFIIH basal transcription factor complex helicase subunit. (849 aa)
LOC106612201Centrin-1-like isoform X2. (219 aa)
LOC106580445Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
xpaDNA-repair protein complementing XP-A cells homolog. (274 aa)
LOC106561926DNA damage-binding protein 1-like isoform X1. (1139 aa)
pole3DNA-directed DNA polymerase epsilon 3. (151 aa)
xpcDNA repair protein complementing XP-C cells. (905 aa)
rfc5Replication factor C subunit 5. (341 aa)
LOC106604249Caltractin-like. (159 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
LOC106584761General transcription factor IIH subunit 1-like. (599 aa)
LOC106605109Replication protein A 32 kDa subunit-like. (278 aa)
LOC106601193-2UV excision repair protein RAD23 homolog A-like isoform X1. (373 aa)
rpa3Replication protein A3. (159 aa)
rfc4Replication factor C subunit 4 isoform X1. (361 aa)
dpoe4DNA-directed DNA polymerase epsilon 4. (130 aa)
ercc8DNA excision repair protein ERCC-8 isoform X1. (400 aa)
LOC106573817UV excision repair protein RAD23 homolog B-like isoform X1. (468 aa)
LOC106570310Replication protein A 14 kDa subunit-like. (147 aa)
pold2DNA polymerase subunit delta-2. (500 aa)
xpa-2DNA repair protein complementing XP-A cells. (278 aa)
cul4bcullin-4B isoform X1; Belongs to the cullin family. (890 aa)
ercc1DNA excision repair protein ERCC-1. (383 aa)
gtf2h3General transcription factor IIH subunit 3. (303 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (567 aa)
ercc6DNA excision repair protein ERCC-6. (1488 aa)
lig1DNA ligase. (1088 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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