STRINGSTRING
perp perp igfbp-3b2 igfbp-3b2 LOC106601568 LOC106601568 ccnd2 ccnd2 LOC106608673 LOC106608673 LOC106610856 LOC106610856 LOC106562137 LOC106562137 ccnd1 ccnd1 LOC106573930 LOC106573930 LOC106572117 LOC106572117 LOC106607826 LOC106607826 LOC106572112 LOC106572112 LOC106575069 LOC106575069 LOC106580524 LOC106580524 chek1 chek1 LOC106600761 LOC106600761 sesn1 sesn1 LOC106565774 LOC106565774 LOC106608163 LOC106608163 LOC106561376 LOC106561376 LOC106587947 LOC106587947 IGFBP-3A2 IGFBP-3A2 IGFBP-3A1 IGFBP-3A1 siva1 siva1 LOC106576445 LOC106576445 LOC106561356 LOC106561356 mdm2 mdm2 LOC106601126 LOC106601126 ENSSSAP00000026568 ENSSSAP00000026568 LOC106600958 LOC106600958 CD82 CD82 LOC106602722 LOC106602722 LOC106570792 LOC106570792 LOC106610834 LOC106610834 LOC106606904 LOC106606904 LOC106603268 LOC106603268 LOC106567336 LOC106567336 SERPINE1 SERPINE1 LOC106569074 LOC106569074 LOC106609475 LOC106609475 LOC106585368 LOC106585368 LOC106576262 LOC106576262 LOC106560326 LOC106560326 atm atm LOC106613608 LOC106613608 gorab gorab LOC106563139 LOC106563139 LOC106569473 LOC106569473 siah1 siah1 LOC106583949 LOC106583949 LOC106603373 LOC106603373 LOC106609566 LOC106609566 LOC106581525 LOC106581525 LOC106588840 LOC106588840 LOC106587134 LOC106587134 LOC106585648 LOC106585648 LOC106566708 LOC106566708 tp53 tp53 LOC106571802 LOC106571802 LOC106567553 LOC106567553 steap3 steap3 LOC106587655 LOC106587655 ccne2 ccne2 ccne2-2 ccne2-2 LOC106593772 LOC106593772 LOC106586584 LOC106586584 LOC106605503 LOC106605503 bclx bclx LOC106607328 LOC106607328 LOC106580118 LOC106580118 LOC106562012 LOC106562012 cd37 cd37 LOC106585195 LOC106585195 LOC106568527 LOC106568527 aifm2 aifm2 LOC106608947 LOC106608947 LOC106571097 LOC106571097 ZMAT3 ZMAT3 LOC106584172 LOC106584172 LOC106589390 LOC106589390 LOC106573709 LOC106573709 LOC106584775 LOC106584775 LOC106584781 LOC106584781 LOC106586251 LOC106586251 LOC106567216 LOC106567216 LOC106566617 LOC106566617 cdk6 cdk6 LOC106587173 LOC106587173 LOC106582467 LOC106582467 LOC106574427 LOC106574427 cdc2 cdc2 zmat3 zmat3 LOC106612018 LOC106612018 LOC106568974 LOC106568974 perp-2 perp-2 LOC106584955 LOC106584955 LOC106567842 LOC106567842 tp53i3 tp53i3 casp9 casp9 LOC106579593 LOC106579593 LOC106567147 LOC106567147 LOC106598934 LOC106598934 LOC106586254 LOC106586254 ga45g ga45g CCND1 CCND1 LOC106581827 LOC106581827 LOC106607213 LOC106607213 tnr6 tnr6 mdm4 mdm4 LOC106599248 LOC106599248 LOC106565657 LOC106565657 LOC106611768 LOC106611768 LOC106578954 LOC106578954 LOC106577010 LOC106577010 LOC106569189 LOC106569189 BCL2 BCL2 LOC106580050 LOC106580050 CCNG2 CCNG2 cop1 cop1 LOC106561972 LOC106561972 casp3 casp3 IGFBP3 IGFBP3 ccnb2 ccnb2 LOC106577554 LOC106577554 LOC106583090 LOC106583090 LOC106583085 LOC106583085 CDK4 CDK4 cdk2 cdk2 BCL2L1 BCL2L1 LOC106563370 LOC106563370 LOC106563369 LOC106563369 ccnb1 ccnb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
perpP53 apoptosis effector related to PMP-22. (185 aa)
igfbp-3b2Insulin-like growth factor binding protein 3 paralog B2 precursor. (288 aa)
LOC106601568G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (310 aa)
ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (296 aa)
LOC106608673Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
LOC106610856Apoptosis regulatory protein Siva-like isoform X1. (166 aa)
LOC106562137G2/mitotic-specific cyclin-B1-like isoform X1; Belongs to the cyclin family. (427 aa)
ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
LOC106573930Growth arrest and DNA damage-inducible protein GADD45 beta-like. (160 aa)
LOC106572117cyclin-G2-like; Belongs to the cyclin family. (356 aa)
LOC106607826Cyclin-dependent kinase 1-like; Belongs to the protein kinase superfamily. (302 aa)
LOC106572112Bcl-2-like protein 1. (230 aa)
LOC106575069Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC106580524Tumor necrosis factor receptor superfamily member 10A-like isoform X2. (421 aa)
chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (480 aa)
LOC106600761Apoptosis regulator BAX-like isoform X2. (201 aa)
sesn1Sestrin-1 isoform X1. (549 aa)
LOC106565774Apoptosis regulator Bcl-X. (216 aa)
LOC106608163Thrombospondin-1-like. (1172 aa)
LOC106561376Uncharacterized protein LOC106561376. (182 aa)
LOC106587947Tetraspanin. (298 aa)
IGFBP-3A2Insulin-like growth factor binding protein 3 paralog A2 precursor. (294 aa)
IGFBP-3A1Insulin-like growth factor binding protein 3 paralog A1 precursor. (296 aa)
siva1Apoptosis regulatory protein Siva. (171 aa)
LOC106576445Apoptotic protease-activating factor 1-like isoform X1. (1274 aa)
LOC106561356G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (298 aa)
mdm2E3 ubiquitin-protein ligase Mdm2. (210 aa)
LOC106601126Apoptosis regulator BAX-like. (225 aa)
ENSSSAP00000026568annotation not available (154 aa)
LOC106600958Cyclin-dependent kinase 6-like; Belongs to the protein kinase superfamily. (301 aa)
CD82Tetraspanin. (302 aa)
LOC106602722Caspase-3-like; Belongs to the peptidase C14A family. (284 aa)
LOC106570792Ribonucleoside-diphosphate reductase subunit M2 B-like. (574 aa)
LOC106610834Thrombospondin-1-like. (1193 aa)
LOC106606904G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (307 aa)
LOC106603268Protein phosphatase 1D-like isoform X2. (591 aa)
LOC106567336Protein reprimo A-like. (108 aa)
SERPINE1Plasminogen activator inhibitor 1-like; Belongs to the serpin family. (391 aa)
LOC106569074E3 ubiquitin-protein ligase RFWD2-like isoform X3. (739 aa)
LOC106609475Insulin-like growth factor I isoform X1. (211 aa)
LOC106585368RING finger and CHY zinc finger domain-containing protein 1-like isoform X2. (304 aa)
LOC106576262G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (301 aa)
LOC106560326Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (250 aa)
atmNon-specific serine/threonine protein kinase. (3172 aa)
LOC106613608Growth arrest and DNA damage-inducible protein GADD45 beta-like. (158 aa)
gorabRAB6-interacting golgin. (406 aa)
LOC106563139Tumor necrosis factor receptor superfamily member 10A-like. (455 aa)
LOC106569473Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (427 aa)
siah1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (335 aa)
LOC106583949Apoptosis regulator BAX-like isoform X2. (202 aa)
LOC106603373Sestrin-3-like isoform X2. (759 aa)
LOC106609566Apoptotic protease-activating factor 1-like isoform X1. (1358 aa)
LOC106581525Protein phosphatase 1D-like. (583 aa)
LOC106588840Cytochrome c iso-1/iso-2-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC106587134Apoptosis regulator BAX-like. (204 aa)
LOC106585648Serine/threonine-protein kinase Chk2-like isoform X2. (546 aa)
LOC106566708G2/mitotic-specific cyclin-B1-like; Belongs to the cyclin family. (403 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (454 aa)
LOC106571802Sestrin-1-like isoform X1. (523 aa)
LOC106567553Tumor necrosis factor receptor superfamily member 10A-like. (460 aa)
steap3Metalloreductase STEAP3 isoform X1. (490 aa)
LOC106587655Thrombospondin-1-like. (1231 aa)
ccne2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (395 aa)
ccne2-2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (420 aa)
LOC106593772E3 ubiquitin-protein ligase Mdm2-like. (279 aa)
LOC106586584Metalloreductase STEAP3-like isoform X1. (492 aa)
LOC106605503Brain-specific angiogenesis inhibitor 1-like isoform X1; Belongs to the G-protein coupled receptor 2 family. (1631 aa)
bclxApoptosis regulator Bcl-X isoform X1. (228 aa)
LOC106607328Apoptosis regulator BAX-like. (194 aa)
LOC106580118Serine/threonine-protein kinase Chk2-like isoform X1. (508 aa)
LOC106562012G1/S-specific cyclin-E1-like isoform X1; Belongs to the cyclin family. (410 aa)
cd37Tetraspanin. (336 aa)
LOC106585195Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (161 aa)
LOC106568527cyclin-G2-like; Belongs to the cyclin family. (338 aa)
aifm2Apoptosis-inducing factor 2. (369 aa)
LOC106608947Plasminogen activator inhibitor 1-like; Belongs to the serpin family. (388 aa)
LOC106571097Thrombospondin-1-like. (1193 aa)
ZMAT3Zinc finger matrin-type protein 3-like. (380 aa)
LOC106584172Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (157 aa)
LOC106589390Phosphatase and tensin homolog B; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (522 aa)
LOC106573709E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (342 aa)
LOC106584775Hermansky-Pudlak syndrome 5 protein-like. (763 aa)
LOC106584781P53-induced death domain-containing protein 1-like. (493 aa)
LOC106586251Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
LOC106567216Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (140 aa)
LOC106566617Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (215 aa)
cdk6Cyclin-dependent kinase 6-like; Belongs to the protein kinase superfamily. (351 aa)
LOC106587173G2/mitotic-specific cyclin-B1-like; Belongs to the cyclin family. (369 aa)
LOC106582467Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC106574427Metalloreductase STEAP3-like isoform X3. (507 aa)
cdc2Cell division control protein 2 homolog; Belongs to the protein kinase superfamily. (302 aa)
zmat3Zinc finger matrin-type protein 3 isoform X1. (458 aa)
LOC106612018Caspase-3-like; Belongs to the peptidase C14A family. (283 aa)
LOC106568974Growth arrest and DNA damage-inducible protein GADD45 alpha-like isoform X1. (159 aa)
perp-2P53 apoptosis effector related to PMP-22. (185 aa)
LOC106584955Tumor necrosis factor receptor superfamily member 10B-like isoform X2. (438 aa)
LOC106567842Sestrin-3-like isoform X2. (525 aa)
tp53i3Quinone oxidoreductase PIG3 isoform X1. (382 aa)
casp9Caspase-9 isoform X1; Belongs to the peptidase C14A family. (450 aa)
LOC106579593Apoptosis regulator Bcl-2-like. (228 aa)
LOC106567147Caspase-9-like; Belongs to the peptidase C14A family. (456 aa)
LOC106598934Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (160 aa)
LOC106586254Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (581 aa)
ga45gGrowth arrest and DNA-damage-inducible protein GADD45 gamma. (161 aa)
CCND1G1/S-specific cyclin-D1-like; Belongs to the cyclin family. (291 aa)
LOC106581827Protein reprimo A-like. (99 aa)
LOC106607213Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (446 aa)
tnr6Tumor necrosis factor receptor superfamily member 6 precursor. (330 aa)
mdm4Protein Mdm4 isoform X2; Belongs to the MDM2/MDM4 family. (541 aa)
LOC106599248Apoptosis regulator Bcl-2-like. (226 aa)
LOC106565657Cyclin-dependent kinase inhibitor 1-like isoform X2. (211 aa)
LOC106611768Sestrin-3-like. (463 aa)
LOC106578954Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (433 aa)
LOC106577010Tumor necrosis factor receptor superfamily member 6-like isoform X1. (391 aa)
LOC106569189Apoptosis regulator Bcl-2-like isoform X2. (226 aa)
BCL2Apoptosis regulator Bcl-2-like. (230 aa)
LOC106580050RING finger and CHY zinc finger domain-containing protein 1-like. (278 aa)
CCNG2Cyclin-G2-like. (356 aa)
cop1E3 ubiquitin-protein ligase RFWD2 isoform X1. (732 aa)
LOC106561972Apoptosis regulator BAX-like. (204 aa)
casp3Caspase 3B; Belongs to the peptidase C14A family. (311 aa)
IGFBP3Insulin-like growth factor binding protein 3 paralog B1 precursor. (299 aa)
ccnb2G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (390 aa)
LOC106577554Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
LOC106583090G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (306 aa)
LOC106583085Cyclin-dependent kinase inhibitor 1B-like isoform X1. (157 aa)
CDK4Cyclin-dependent kinase 4-like isoform X1; Belongs to the protein kinase superfamily. (305 aa)
cdk2Cell division protein kinase 2; Belongs to the protein kinase superfamily. (298 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
LOC106563370Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (154 aa)
LOC106563369Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (140 aa)
ccnb1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (401 aa)
Your Current Organism:
Salmo salar
NCBI taxonomy Id: 8030
Other names: Atlantic salmon, S. salar
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