(17 nodes) L27 domain, C-terminal, and Dopamine Neurotransmitter Release Cycle network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000000287	Uncharacterized protein. (452 aa)
	ENSFHEP00000002496	CaMKII_AD domain-containing protein. (192 aa)
	LOC105921365	Amyloid beta precursor protein binding family A member 1. (1123 aa)
	mpp1	Membrane protein, palmitoylated 1; Belongs to the MAGUK family. (470 aa)
	LOC105935630	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (547 aa)
	lin7b	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (220 aa)
	LOC105938620	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (850 aa)
	LOC105926377	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (551 aa)
	LOC105938289	Amyloid beta precursor protein binding family A member 3. (699 aa)
	LOC105916295	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (934 aa)
	lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (224 aa)
	ENSFHEP00000027115	PDZ domain-containing protein. (153 aa)
	CASK	Uncharacterized protein; Belongs to the MAGUK family. (897 aa)
	LOC105934314	Uncharacterized protein; Belongs to the MAGUK family. (553 aa)
	lin7c	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (201 aa)
	LOC105921523	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (960 aa)
	ENSFHEP00000035195	Protein kinase domain-containing protein. (275 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASK	ENSFHEP00000000287	ENSFHEP00000027213	ENSFHEP00000000287	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.958
CASK	ENSFHEP00000027115	ENSFHEP00000027213	ENSFHEP00000027115	Uncharacterized protein; Belongs to the MAGUK family.	PDZ domain-containing protein.	0.967
CASK	LOC105916295	ENSFHEP00000027213	ENSFHEP00000017890	Uncharacterized protein; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2b.	0.958
CASK	LOC105921365	ENSFHEP00000027213	ENSFHEP00000004109	Uncharacterized protein; Belongs to the MAGUK family.	Amyloid beta precursor protein binding family A member 1.	0.958
CASK	LOC105921523	ENSFHEP00000027213	ENSFHEP00000032900	Uncharacterized protein; Belongs to the MAGUK family.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.810
CASK	LOC105938289	ENSFHEP00000027213	ENSFHEP00000015387	Uncharacterized protein; Belongs to the MAGUK family.	Amyloid beta precursor protein binding family A member 3.	0.958
CASK	LOC105938620	ENSFHEP00000027213	ENSFHEP00000009499	Uncharacterized protein; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	0.958
CASK	lin7a	ENSFHEP00000027213	ENSFHEP00000019604	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	lin7b	ENSFHEP00000027213	ENSFHEP00000009092	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	lin7c	ENSFHEP00000027213	ENSFHEP00000032456	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.967
CASK	mpp1	ENSFHEP00000027213	ENSFHEP00000004472	Uncharacterized protein; Belongs to the MAGUK family.	Membrane protein, palmitoylated 1; Belongs to the MAGUK family.	0.676
ENSFHEP00000000287	CASK	ENSFHEP00000000287	ENSFHEP00000027213	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.958
ENSFHEP00000000287	ENSFHEP00000002496	ENSFHEP00000000287	ENSFHEP00000002496	Uncharacterized protein.	CaMKII_AD domain-containing protein.	0.658
ENSFHEP00000000287	ENSFHEP00000027115	ENSFHEP00000000287	ENSFHEP00000027115	Uncharacterized protein.	PDZ domain-containing protein.	0.677
ENSFHEP00000000287	ENSFHEP00000035195	ENSFHEP00000000287	ENSFHEP00000035195	Uncharacterized protein.	Protein kinase domain-containing protein.	0.658
ENSFHEP00000000287	LOC105921523	ENSFHEP00000000287	ENSFHEP00000032900	Uncharacterized protein.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.958
ENSFHEP00000000287	LOC105926377	ENSFHEP00000000287	ENSFHEP00000013967	Uncharacterized protein.	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family.	0.748
ENSFHEP00000000287	LOC105934314	ENSFHEP00000000287	ENSFHEP00000030595	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.748
ENSFHEP00000000287	LOC105935630	ENSFHEP00000000287	ENSFHEP00000005344	Uncharacterized protein.	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.748
ENSFHEP00000000287	lin7a	ENSFHEP00000000287	ENSFHEP00000019604	Uncharacterized protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.677