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ncbp2 ncbp2 snrpf snrpf prpf31 prpf31 snrnp200 snrnp200 lix1l lix1l spaca6 spaca6 snrnp70 snrnp70 SART1 SART1 lsm3 lsm3 snrpd3 snrpd3 sf3a1 sf3a1 phf5a phf5a NCBP1 NCBP1 ENSFHEP00000012172 ENSFHEP00000012172 snrpd2 snrpd2 txnl4a txnl4a snrpc snrpc sf3b3 sf3b3 sf3a3 sf3a3 ddx46 ddx46 sf3b5 sf3b5 prpf8 prpf8 prpf3 prpf3 LSM10 LSM10 prpf4 prpf4 sf3a2 sf3a2 snrpa snrpa ENSFHEP00000024755 ENSFHEP00000024755 snrnp40 snrnp40 SNRPG SNRPG eftud2 eftud2 snrpb2 snrpb2 ddx23 ddx23 snrpa1 snrpa1 snrpe snrpe sf3b2 sf3b2 prpf6 prpf6 sf3b6 sf3b6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
snrpfSmall nuclear ribonucleoprotein polypeptide F. (114 aa)
prpf31PRP31 pre-mRNA processing factor 31 homolog (yeast). (569 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2084 aa)
lix1lSplicing factor 3b, subunit 4. (689 aa)
spaca6Ig-like domain-containing protein. (334 aa)
snrnp70Small nuclear ribonucleoprotein 70 (U1). (469 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (773 aa)
lsm3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
snrpd3Small nuclear ribonucleoprotein Sm D3. (127 aa)
sf3a1Splicing factor 3a, subunit 1. (851 aa)
phf5aPHD finger protein 5A. (110 aa)
NCBP1Nuclear cap binding protein subunit 1. (796 aa)
ENSFHEP00000012172Small nuclear ribonucleoprotein D1 polypeptide. (82 aa)
snrpd2Small nuclear ribonucleoprotein Sm D2. (118 aa)
txnl4aThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
snrpcU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (112 aa)
sf3b3Splicing factor 3b, subunit 3. (1217 aa)
sf3a3Splicing factor 3a, subunit 3. (501 aa)
ddx46ATP-dependent RNA helicase DDX46, putative. (1067 aa)
sf3b5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
prpf8Pre-mRNA processing factor 8. (2342 aa)
prpf3PRP3 pre-mRNA processing factor 3 homolog (yeast). (685 aa)
LSM10LSM10, U7 small nuclear RNA associated. (116 aa)
prpf4PRP4 pre-mRNA processing factor 4 homolog (yeast). (510 aa)
sf3a2Splicing factor 3a, subunit 2. (293 aa)
snrpaSmall nuclear ribonucleoprotein polypeptide A. (270 aa)
ENSFHEP00000024755Sm domain-containing protein. (73 aa)
snrnp40Small nuclear ribonucleoprotein 40 (U5). (347 aa)
SNRPGSmall nuclear ribonucleoprotein G. (138 aa)
eftud2116 kDa U5 small nuclear ribonucleoprotein component. (971 aa)
snrpb2Small nuclear ribonucleoprotein polypeptide B2. (208 aa)
ddx23DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (804 aa)
snrpa1Small nuclear ribonucleoprotein polypeptide A. (259 aa)
snrpeSmall nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (137 aa)
sf3b2Splicing factor 3b, subunit 2. (855 aa)
prpf6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (968 aa)
sf3b6Splicing factor 3b, subunit 6. (125 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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