(24 nodes) Mixed, incl. UTP metabolic process, and Ribonucleoside-diphosphate reductase activity network (Fundulus heteroclitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	LOC105929512	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1189 aa)
	ENTPD7	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
	LOC105935717	Nucleoside diphosphate kinase. (152 aa)
	LOC105915363	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (495 aa)
	guk1	Guanylate kinase 1a. (211 aa)
	ntpcr	Nucleoside-triphosphatase, cancer-related. (203 aa)
	ctps1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (593 aa)
	LOC105918684	Ribonucleotide reductase M2 polypeptide. (389 aa)
	LOC105935238	Adenylate cyclase 1b. (941 aa)
	LOC105921658	NDK domain-containing protein; Belongs to the NDK family. (242 aa)
	LOC105928544	Ribonucleotide reductase M2 b. (355 aa)
	nme3	Nucleoside diphosphate kinase. (180 aa)
	nudt2	Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (147 aa)
	LOC105929370	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (799 aa)
	ENSFHEP00000023035	NDK domain-containing protein. (153 aa)
	LOC105939143	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (802 aa)
	LOC105936784	Guanylate kinase 1b. (159 aa)
	nme7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (374 aa)
	ak3	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (219 aa)
	nme5	NME/NM23 family member 5; Belongs to the NDK family. (210 aa)
	entpd2	Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. (482 aa)
	hddc3	HD domain containing 3. (179 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	LOC105939913	Nucleoside diphosphate kinase. (202 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000023035	ENTPD7	ENSFHEP00000023035	ENSFHEP00000001817	NDK domain-containing protein.	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family.	0.672
ENSFHEP00000023035	LOC105915363	ENSFHEP00000023035	ENSFHEP00000010365	NDK domain-containing protein.	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	0.602
ENSFHEP00000023035	LOC105918684	ENSFHEP00000023035	ENSFHEP00000013413	NDK domain-containing protein.	Ribonucleotide reductase M2 polypeptide.	0.788
ENSFHEP00000023035	LOC105921658	ENSFHEP00000023035	ENSFHEP00000014262	NDK domain-containing protein.	NDK domain-containing protein; Belongs to the NDK family.	0.902
ENSFHEP00000023035	LOC105928544	ENSFHEP00000023035	ENSFHEP00000017849	NDK domain-containing protein.	Ribonucleotide reductase M2 b.	0.898
ENSFHEP00000023035	LOC105929370	ENSFHEP00000023035	ENSFHEP00000022330	NDK domain-containing protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.907
ENSFHEP00000023035	LOC105929512	ENSFHEP00000023035	ENSFHEP00000000409	NDK domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.685
ENSFHEP00000023035	LOC105935238	ENSFHEP00000023035	ENSFHEP00000013703	NDK domain-containing protein.	Adenylate cyclase 1b.	0.893
ENSFHEP00000023035	LOC105936784	ENSFHEP00000023035	ENSFHEP00000024894	NDK domain-containing protein.	Guanylate kinase 1b.	0.916
ENSFHEP00000023035	LOC105939143	ENSFHEP00000023035	ENSFHEP00000024685	NDK domain-containing protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.907
ENSFHEP00000023035	LOC105939913	ENSFHEP00000023035	ENSFHEP00000033745	NDK domain-containing protein.	Nucleoside diphosphate kinase.	0.945
ENSFHEP00000023035	ak3	ENSFHEP00000023035	ENSFHEP00000027652	NDK domain-containing protein.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.922
ENSFHEP00000023035	ctps1	ENSFHEP00000023035	ENSFHEP00000011476	NDK domain-containing protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.927
ENSFHEP00000023035	entpd2	ENSFHEP00000023035	ENSFHEP00000030201	NDK domain-containing protein.	Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family.	0.902
ENSFHEP00000023035	guk1	ENSFHEP00000023035	ENSFHEP00000010451	NDK domain-containing protein.	Guanylate kinase 1a.	0.916
ENSFHEP00000023035	hddc3	ENSFHEP00000023035	ENSFHEP00000032067	NDK domain-containing protein.	HD domain containing 3.	0.927
ENSFHEP00000023035	nme3	ENSFHEP00000023035	ENSFHEP00000018159	NDK domain-containing protein.	Nucleoside diphosphate kinase.	0.910
ENSFHEP00000023035	nme5	ENSFHEP00000023035	ENSFHEP00000028789	NDK domain-containing protein.	NME/NM23 family member 5; Belongs to the NDK family.	0.655
ENSFHEP00000023035	nme6	ENSFHEP00000023035	ENSFHEP00000032831	NDK domain-containing protein.	Nucleoside diphosphate kinase.	0.939
ENSFHEP00000023035	nme7	ENSFHEP00000023035	ENSFHEP00000026989	NDK domain-containing protein.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.906