(43 nodes) Zinc finger, NHR/GATA-type, and Nuclear receptor coactivator network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105938548	Peroxisome proliferator-activated receptor alpha b. (469 aa)
	LOC105928653	Vitellogenin 3, phosvitinless. (1227 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (508 aa)
	nrip1	Nuclear receptor interacting protein 1b. (1203 aa)
	LOC105926046	Endothelial transcription factor GATA-2. (462 aa)
	PRMT8	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (401 aa)
	ENSFHEP00000005412	Nuclear receptor coactivator 1. (971 aa)
	GATA2	Endothelial transcription factor GATA-2. (460 aa)
	foxa2	Forkhead box A2. (426 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (489 aa)
	ppara	Peroxisome proliferator-activated receptor alpha a. (490 aa)
	LOC105939110	Nuclear receptor subfamily 1, group D, member 4b. (644 aa)
	trps1	Trichorhinophalangeal syndrome I. (1397 aa)
	LOC105936755	Nuclear receptor subfamily 1, group D, member 2a. (577 aa)
	LOC105936476	Uncharacterized protein. (351 aa)
	LOC105925883	Vitamin D receptor a. (420 aa)
	LOC105935507	Estrogen receptor 2b. (673 aa)
	RXRB	Retinoid X receptor beta. (361 aa)
	LOC105937897	Uncharacterized protein. (448 aa)
	LOC105917026	Uncharacterized protein. (811 aa)
	LOC105926355	Retinoic acid receptor RXR-beta. (444 aa)
	LOC105935418	Estrogen receptor 2a. (553 aa)
	LOC105940391	Thyroid hormone receptor alpha. (413 aa)
	NCOA3	Nuclear receptor coactivator 3. (1489 aa)
	nr1d2	Nuclear receptor subfamily 1, group D, member 2b. (598 aa)
	LOC105922411	Nuclear receptor coactivator 3. (1519 aa)
	LOC105933104	Forkhead box A3. (463 aa)
	LOC105915987	Protein arginine methyltransferase 8b; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (401 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (464 aa)
	LOC105927864	Retinoic acid receptor RXR-beta. (471 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (533 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (620 aa)
	carm1	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (590 aa)
	LOC105921450	Prostate transmembrane protein, androgen induced 1. (324 aa)
	NCOA2	Nuclear receptor coactivator. (1494 aa)
	foxa1	Fork-head domain-containing protein. (412 aa)
	LOC105931721	Vitamin D receptor b. (425 aa)
	LOC105925854	Nuclear receptor subfamily 1, group H, member 5. (494 aa)
	nr4a3	Nuclear receptor subfamily 4, group A, member 3. (681 aa)
	rxra	Retinoid X receptor, alpha a. (501 aa)
	nr1i2	Uncharacterized protein. (439 aa)
	ncoa2	Nuclear receptor coactivator. (1446 aa)
	thrb	Thyroid hormone receptor beta. (395 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000005412	GATA2	ENSFHEP00000005412	ENSFHEP00000006111	Nuclear receptor coactivator 1.	Endothelial transcription factor GATA-2.	0.505
ENSFHEP00000005412	LOC105915987	ENSFHEP00000005412	ENSFHEP00000019626	Nuclear receptor coactivator 1.	Protein arginine methyltransferase 8b; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.417
ENSFHEP00000005412	LOC105917026	ENSFHEP00000005412	ENSFHEP00000011391	Nuclear receptor coactivator 1.	Uncharacterized protein.	0.671
ENSFHEP00000005412	LOC105925854	ENSFHEP00000005412	ENSFHEP00000028266	Nuclear receptor coactivator 1.	Nuclear receptor subfamily 1, group H, member 5.	0.830
ENSFHEP00000005412	LOC105925883	ENSFHEP00000005412	ENSFHEP00000008403	Nuclear receptor coactivator 1.	Vitamin D receptor a.	0.792
ENSFHEP00000005412	LOC105926046	ENSFHEP00000005412	ENSFHEP00000004585	Nuclear receptor coactivator 1.	Endothelial transcription factor GATA-2.	0.505
ENSFHEP00000005412	LOC105926355	ENSFHEP00000005412	ENSFHEP00000012750	Nuclear receptor coactivator 1.	Retinoic acid receptor RXR-beta.	0.794
ENSFHEP00000005412	LOC105927864	ENSFHEP00000005412	ENSFHEP00000020790	Nuclear receptor coactivator 1.	Retinoic acid receptor RXR-beta.	0.794
ENSFHEP00000005412	LOC105931721	ENSFHEP00000005412	ENSFHEP00000024951	Nuclear receptor coactivator 1.	Vitamin D receptor b.	0.792
ENSFHEP00000005412	LOC105935418	ENSFHEP00000005412	ENSFHEP00000014291	Nuclear receptor coactivator 1.	Estrogen receptor 2a.	0.744
ENSFHEP00000005412	LOC105935507	ENSFHEP00000005412	ENSFHEP00000010364	Nuclear receptor coactivator 1.	Estrogen receptor 2b.	0.733
ENSFHEP00000005412	LOC105936476	ENSFHEP00000005412	ENSFHEP00000007939	Nuclear receptor coactivator 1.	Uncharacterized protein.	0.899
ENSFHEP00000005412	LOC105936755	ENSFHEP00000005412	ENSFHEP00000007611	Nuclear receptor coactivator 1.	Nuclear receptor subfamily 1, group D, member 2a.	0.736
ENSFHEP00000005412	LOC105937897	ENSFHEP00000005412	ENSFHEP00000011029	Nuclear receptor coactivator 1.	Uncharacterized protein.	0.673
ENSFHEP00000005412	LOC105938548	ENSFHEP00000005412	ENSFHEP00000001764	Nuclear receptor coactivator 1.	Peroxisome proliferator-activated receptor alpha b.	0.716
ENSFHEP00000005412	LOC105939110	ENSFHEP00000005412	ENSFHEP00000007563	Nuclear receptor coactivator 1.	Nuclear receptor subfamily 1, group D, member 4b.	0.736
ENSFHEP00000005412	LOC105940391	ENSFHEP00000005412	ENSFHEP00000014788	Nuclear receptor coactivator 1.	Thyroid hormone receptor alpha.	0.673
ENSFHEP00000005412	NCOA2	ENSFHEP00000005412	ENSFHEP00000023388	Nuclear receptor coactivator 1.	Nuclear receptor coactivator.	0.539
ENSFHEP00000005412	PPARG	ENSFHEP00000005412	ENSFHEP00000021025	Nuclear receptor coactivator 1.	Peroxisome proliferator activated receptor gamma.	0.716
ENSFHEP00000005412	PRMT8	ENSFHEP00000005412	ENSFHEP00000004619	Nuclear receptor coactivator 1.	Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.417