(20 nodes) ATP P2X receptor, and Innexin network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105939307	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (406 aa)
	LOC105920712	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (418 aa)
	usp36	Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1100 aa)
	ENSFHEP00000010216	Uncharacterized protein. (49 aa)
	panx2	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (659 aa)
	LOC105932667	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (381 aa)
	ENSFHEP00000013635	Si:dkey-33o22.1. (92 aa)
	panx1	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (421 aa)
	P2RY4	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	LOC105930221	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (440 aa)
	calhm1	Calcium homeostasis modulator 1. (351 aa)
	ENSFHEP00000027816	Uncharacterized protein. (162 aa)
	p2rx3	Uncharacterized protein. (328 aa)
	calhm3	Calcium homeostasis modulator protein 3. (329 aa)
	p2rx5	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (463 aa)
	p2rx2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (418 aa)
	auts2	Activator of transcription and developmental regulator AUTS2 a. (1070 aa)
	ano6	Anoctamin. (910 aa)
	p2rx7	Purinergic receptor P2X, ligand-gated ion channel, 7. (615 aa)
	spdya	Speedy/RINGO cell cycle regulator family member A. (333 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000010216	ENSFHEP00000013635	ENSFHEP00000010216	ENSFHEP00000013635	Uncharacterized protein.	Si:dkey-33o22.1.	0.477
ENSFHEP00000010216	LOC105920712	ENSFHEP00000010216	ENSFHEP00000006925	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.816
ENSFHEP00000010216	LOC105932667	ENSFHEP00000010216	ENSFHEP00000013424	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.648
ENSFHEP00000010216	LOC105939307	ENSFHEP00000010216	ENSFHEP00000004850	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.823
ENSFHEP00000010216	auts2	ENSFHEP00000010216	ENSFHEP00000030086	Uncharacterized protein.	Activator of transcription and developmental regulator AUTS2 a.	0.551
ENSFHEP00000010216	p2rx2	ENSFHEP00000010216	ENSFHEP00000028682	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.829
ENSFHEP00000010216	p2rx5	ENSFHEP00000010216	ENSFHEP00000028099	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.770
ENSFHEP00000010216	p2rx7	ENSFHEP00000010216	ENSFHEP00000034153	Uncharacterized protein.	Purinergic receptor P2X, ligand-gated ion channel, 7.	0.758
ENSFHEP00000013635	ENSFHEP00000010216	ENSFHEP00000013635	ENSFHEP00000010216	Si:dkey-33o22.1.	Uncharacterized protein.	0.477
ENSFHEP00000013635	ENSFHEP00000027816	ENSFHEP00000013635	ENSFHEP00000027816	Si:dkey-33o22.1.	Uncharacterized protein.	0.477
ENSFHEP00000013635	LOC105932667	ENSFHEP00000013635	ENSFHEP00000013424	Si:dkey-33o22.1.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.530
ENSFHEP00000013635	auts2	ENSFHEP00000013635	ENSFHEP00000030086	Si:dkey-33o22.1.	Activator of transcription and developmental regulator AUTS2 a.	0.865
ENSFHEP00000013635	p2rx2	ENSFHEP00000013635	ENSFHEP00000028682	Si:dkey-33o22.1.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.658
ENSFHEP00000013635	p2rx3	ENSFHEP00000013635	ENSFHEP00000027888	Si:dkey-33o22.1.	Uncharacterized protein.	0.477
ENSFHEP00000013635	p2rx5	ENSFHEP00000013635	ENSFHEP00000028099	Si:dkey-33o22.1.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.530
ENSFHEP00000013635	p2rx7	ENSFHEP00000013635	ENSFHEP00000034153	Si:dkey-33o22.1.	Purinergic receptor P2X, ligand-gated ion channel, 7.	0.620
ENSFHEP00000013635	spdya	ENSFHEP00000013635	ENSFHEP00000034271	Si:dkey-33o22.1.	Speedy/RINGO cell cycle regulator family member A.	0.571
ENSFHEP00000013635	usp36	ENSFHEP00000013635	ENSFHEP00000007779	Si:dkey-33o22.1.	Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family.	0.538
ENSFHEP00000027816	ENSFHEP00000013635	ENSFHEP00000027816	ENSFHEP00000013635	Uncharacterized protein.	Si:dkey-33o22.1.	0.477
ENSFHEP00000027816	LOC105920712	ENSFHEP00000027816	ENSFHEP00000006925	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.816