(10 nodes) Endothelin receptor family, and Endothelin network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105921308	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	ednra	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	ENSFHEP00000013818	END domain-containing protein. (156 aa)
	LOC105920392	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
	LOC110369193	Uncharacterized protein. (180 aa)
	LOC105933906	Endothelin 2. (161 aa)
	LOC105923645	Endothelin 1. (218 aa)
	LOC105929187	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
	LOC105930247	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	LOC105933618	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000013818	LOC105921308	ENSFHEP00000013818	ENSFHEP00000006082	END domain-containing protein.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.975
ENSFHEP00000013818	LOC105923645	ENSFHEP00000013818	ENSFHEP00000029605	END domain-containing protein.	Endothelin 1.	0.928
ENSFHEP00000013818	LOC105929187	ENSFHEP00000013818	ENSFHEP00000030189	END domain-containing protein.	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.986
ENSFHEP00000013818	LOC105930247	ENSFHEP00000013818	ENSFHEP00000032548	END domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.978
ENSFHEP00000013818	LOC105933618	ENSFHEP00000013818	ENSFHEP00000034158	END domain-containing protein.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.978
ENSFHEP00000013818	LOC105933906	ENSFHEP00000013818	ENSFHEP00000024033	END domain-containing protein.	Endothelin 2.	0.761
ENSFHEP00000013818	ednra	ENSFHEP00000013818	ENSFHEP00000006902	END domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.982
LOC105920392	LOC105921308	ENSFHEP00000014509	ENSFHEP00000006082	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.561
LOC105920392	LOC105929187	ENSFHEP00000014509	ENSFHEP00000030189	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.962
LOC105920392	LOC105930247	ENSFHEP00000014509	ENSFHEP00000032548	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.962
LOC105920392	LOC105933618	ENSFHEP00000014509	ENSFHEP00000034158	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.962
LOC105920392	ednra	ENSFHEP00000014509	ENSFHEP00000006902	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.561
LOC105921308	ENSFHEP00000013818	ENSFHEP00000006082	ENSFHEP00000013818	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	END domain-containing protein.	0.975
LOC105921308	LOC105920392	ENSFHEP00000006082	ENSFHEP00000014509	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.	0.561
LOC105921308	LOC105923645	ENSFHEP00000006082	ENSFHEP00000029605	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.997
LOC105921308	LOC105929187	ENSFHEP00000006082	ENSFHEP00000030189	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.791
LOC105921308	LOC105930247	ENSFHEP00000006082	ENSFHEP00000032548	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.708
LOC105921308	LOC105933618	ENSFHEP00000006082	ENSFHEP00000034158	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.707
LOC105921308	LOC105933906	ENSFHEP00000006082	ENSFHEP00000024033	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin 2.	0.958
LOC105921308	LOC110369193	ENSFHEP00000006082	ENSFHEP00000016583	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.977