(11 nodes) Mixed, incl. Activation of RAC1 downstream of NMDARs, and Transient receptor potential cation channel subfamily V network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000012387	Ig-like domain-containing protein. (127 aa)
	calm2	Calmodulin 2. (149 aa)
	LOC110367401	Protein kinase domain-containing protein. (211 aa)
	LOC105918262	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily. (485 aa)
	trpv5	Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family. (728 aa)
	calml4	Calmodulin-like 4a. (153 aa)
	LOC105936550	Uncharacterized protein; Belongs to the calmodulin family. (207 aa)
	camk1d	Calcium/calmodulin-dependent protein kinase ID, putative; Belongs to the protein kinase superfamily. (435 aa)
	LOC105934766	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
	LOC105930730	Hippocalcin-like 1. (239 aa)
	LOC105935895	CaM kinase-like vesicle-associated, like. (803 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000012387	LOC105936550	ENSFHEP00000012387	ENSFHEP00000030939	Ig-like domain-containing protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.874
ENSFHEP00000012387	calm2	ENSFHEP00000012387	ENSFHEP00000018773	Ig-like domain-containing protein.	Calmodulin 2.	0.521
ENSFHEP00000012387	calml4	ENSFHEP00000012387	ENSFHEP00000030503	Ig-like domain-containing protein.	Calmodulin-like 4a.	0.780
LOC105918262	LOC105934766	ENSFHEP00000029078	ENSFHEP00000033639	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.558
LOC105918262	LOC105935895	ENSFHEP00000029078	ENSFHEP00000034148	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	CaM kinase-like vesicle-associated, like.	0.546
LOC105918262	LOC105936550	ENSFHEP00000029078	ENSFHEP00000030939	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the calmodulin family.	0.823
LOC105918262	calm2	ENSFHEP00000029078	ENSFHEP00000018773	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	Calmodulin 2.	0.708
LOC105918262	calml4	ENSFHEP00000029078	ENSFHEP00000030503	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	Calmodulin-like 4a.	0.934
LOC105918262	camk1d	ENSFHEP00000029078	ENSFHEP00000032153	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	Calcium/calmodulin-dependent protein kinase ID, putative; Belongs to the protein kinase superfamily.	0.559
LOC105930730	LOC105936550	ENSFHEP00000033834	ENSFHEP00000030939	Hippocalcin-like 1.	Uncharacterized protein; Belongs to the calmodulin family.	0.646
LOC105930730	calm2	ENSFHEP00000033834	ENSFHEP00000018773	Hippocalcin-like 1.	Calmodulin 2.	0.646
LOC105934766	LOC105918262	ENSFHEP00000033639	ENSFHEP00000029078	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	0.558
LOC105934766	LOC105936550	ENSFHEP00000033639	ENSFHEP00000030939	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the calmodulin family.	0.849
LOC105934766	LOC110367401	ENSFHEP00000033639	ENSFHEP00000028163	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.546
LOC105934766	calm2	ENSFHEP00000033639	ENSFHEP00000018773	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Calmodulin 2.	0.695
LOC105934766	calml4	ENSFHEP00000033639	ENSFHEP00000030503	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Calmodulin-like 4a.	0.956
LOC105935895	LOC105918262	ENSFHEP00000034148	ENSFHEP00000029078	CaM kinase-like vesicle-associated, like.	Calcium/calmodulin-dependent protein kinase IGb; Belongs to the protein kinase superfamily.	0.546
LOC105935895	LOC105936550	ENSFHEP00000034148	ENSFHEP00000030939	CaM kinase-like vesicle-associated, like.	Uncharacterized protein; Belongs to the calmodulin family.	0.695
LOC105935895	LOC110367401	ENSFHEP00000034148	ENSFHEP00000028163	CaM kinase-like vesicle-associated, like.	Protein kinase domain-containing protein.	0.546
LOC105935895	calm2	ENSFHEP00000034148	ENSFHEP00000018773	CaM kinase-like vesicle-associated, like.	Calmodulin 2.	0.695