(15 nodes) Resolution of meiotic recombination intermediates network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	shoc1	Uncharacterized protein. (1417 aa)
	rmi1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (687 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (715 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1605 aa)
	ercc4	Excision repair cross-complementation group 4. (897 aa)
	tex11	Testis expressed 11. (903 aa)
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1496 aa)
	ENSFHEP00000005371	Uncharacterized protein. (597 aa)
	ENSFHEP00000005309	Uncharacterized protein. (363 aa)
	mus81	MUS81 structure-specific endonuclease subunit. (612 aa)
	meiob	Methionine sulfoxide reductase B1b. (385 aa)
	ankle1	Zgc:85936. (1133 aa)
	cenpx	Centromere protein X. (95 aa)
	eme1	Essential meiotic structure-specific endonuclease 1. (502 aa)
	top2a	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1525 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000005309	ENSFHEP00000005371	ENSFHEP00000005309	ENSFHEP00000005371	Uncharacterized protein.	Uncharacterized protein.	0.999
ENSFHEP00000005309	cenpx	ENSFHEP00000005309	ENSFHEP00000026017	Uncharacterized protein.	Centromere protein X.	0.990
ENSFHEP00000005309	eme1	ENSFHEP00000005309	ENSFHEP00000025092	Uncharacterized protein.	Essential meiotic structure-specific endonuclease 1.	0.742
ENSFHEP00000005309	ercc4	ENSFHEP00000005309	ENSFHEP00000015698	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.824
ENSFHEP00000005309	meiob	ENSFHEP00000005309	ENSFHEP00000030464	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.999
ENSFHEP00000005309	mlh1	ENSFHEP00000005309	ENSFHEP00000017579	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.689
ENSFHEP00000005309	mus81	ENSFHEP00000005309	ENSFHEP00000001971	Uncharacterized protein.	MUS81 structure-specific endonuclease subunit.	0.999
ENSFHEP00000005309	rmi1	ENSFHEP00000005309	ENSFHEP00000020203	Uncharacterized protein.	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).	0.999
ENSFHEP00000005309	slx4	ENSFHEP00000005309	ENSFHEP00000010922	Uncharacterized protein.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.973
ENSFHEP00000005309	tex11	ENSFHEP00000005309	ENSFHEP00000014364	Uncharacterized protein.	Testis expressed 11.	0.637
ENSFHEP00000005309	top2a	ENSFHEP00000005309	ENSFHEP00000024530	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.616
ENSFHEP00000005309	top2b	ENSFHEP00000005309	ENSFHEP00000017208	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.616
ENSFHEP00000005371	ENSFHEP00000005309	ENSFHEP00000005371	ENSFHEP00000005309	Uncharacterized protein.	Uncharacterized protein.	0.999
ENSFHEP00000005371	cenpx	ENSFHEP00000005371	ENSFHEP00000026017	Uncharacterized protein.	Centromere protein X.	0.990
ENSFHEP00000005371	eme1	ENSFHEP00000005371	ENSFHEP00000025092	Uncharacterized protein.	Essential meiotic structure-specific endonuclease 1.	0.742
ENSFHEP00000005371	ercc4	ENSFHEP00000005371	ENSFHEP00000015698	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.824
ENSFHEP00000005371	meiob	ENSFHEP00000005371	ENSFHEP00000030464	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.999
ENSFHEP00000005371	mlh1	ENSFHEP00000005371	ENSFHEP00000017579	Uncharacterized protein.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.689
ENSFHEP00000005371	mus81	ENSFHEP00000005371	ENSFHEP00000001971	Uncharacterized protein.	MUS81 structure-specific endonuclease subunit.	0.999
ENSFHEP00000005371	rmi1	ENSFHEP00000005371	ENSFHEP00000020203	Uncharacterized protein.	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).	0.999