(11 nodes) Endochondral ossification network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105939829	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	mef2d	Myocyte enhancer factor 2d. (583 aa)
	ENSFHEP00000011863	Transmembrane protein 119b. (281 aa)
	LOC105931924	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	nab2	NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)
	LOC105935060	MADS-box domain-containing protein. (497 aa)
	pex7	Peroxisomal biogenesis factor 7. (324 aa)
	ift80	Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa)
	LOC105916516	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	LOC105935872	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (706 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105916516	LOC105931924	ENSFHEP00000032621	ENSFHEP00000018900	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.425
LOC105916516	LOC105935872	ENSFHEP00000032621	ENSFHEP00000033555	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.953
LOC105931924	LOC105916516	ENSFHEP00000018900	ENSFHEP00000032621	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.425
LOC105935872	LOC105916516	ENSFHEP00000033555	ENSFHEP00000032621	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.953