23 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hlx	H2.0-like homeo box 1 (Drosophila). (394 aa)
	gpr183	G protein-coupled receptor 183a; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	fgl2	Fibrinogen-like 2a. (502 aa)
	lef1	Lymphoid enhancer-binding factor 1. (424 aa)
	LOC105933857	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (481 aa)
	LOC105928759	Prostaglandin E receptor 4 (subtype EP4) b. (460 aa)
	LOC105928499	Uncharacterized protein. (609 aa)
	LOC105928473	Interleukin 6 receptor. (583 aa)
	ENSFHEP00000017372	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (397 aa)
	ENSFHEP00000016845	Ig-like domain-containing protein. (96 aa)
	LOC105927446	TSC complex subunit 1b. (1254 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
	tmem98	Transmembrane protein 98. (224 aa)
	LOC105927509	Si:ch211-184m13.4; Belongs to the G-protein coupled receptor 1 family. (332 aa)
	LOC105919467	TSC complex subunit 1. (1034 aa)
	LOC105927108	Angiopoietin-related protein. (424 aa)
	tbx21	T-box transcription factor 21. (614 aa)
	batf	Basic leucine zipper transcription factor, ATF-like. (124 aa)
	LOC105929581	Si:ch211-203k16.3. (346 aa)
	LOC105937903	Uncharacterized protein. (181 aa)
	rc3h2	Ring finger and CCCH-type domains 2. (1122 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1654 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1168 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	LOC105919467	ENSFHEP00000029640	ENSFHEP00000007990	Eukaryotic translation initiation factor 2 alpha kinase 4.	TSC complex subunit 1.	0.499
EIF2AK4	LOC105927446	ENSFHEP00000029640	ENSFHEP00000013621	Eukaryotic translation initiation factor 2 alpha kinase 4.	TSC complex subunit 1b.	0.499
EIF2AK4	mtor	ENSFHEP00000029640	ENSFHEP00000010587	Eukaryotic translation initiation factor 2 alpha kinase 4.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.921
LOC105919467	EIF2AK4	ENSFHEP00000007990	ENSFHEP00000029640	TSC complex subunit 1.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.499
LOC105919467	LOC105927446	ENSFHEP00000007990	ENSFHEP00000013621	TSC complex subunit 1.	TSC complex subunit 1b.	0.911
LOC105919467	mtor	ENSFHEP00000007990	ENSFHEP00000010587	TSC complex subunit 1.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.935
LOC105927446	EIF2AK4	ENSFHEP00000013621	ENSFHEP00000029640	TSC complex subunit 1b.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.499
LOC105927446	LOC105919467	ENSFHEP00000013621	ENSFHEP00000007990	TSC complex subunit 1b.	TSC complex subunit 1.	0.911
LOC105927446	mtor	ENSFHEP00000013621	ENSFHEP00000010587	TSC complex subunit 1b.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.935
LOC105928473	LOC105937903	ENSFHEP00000017376	ENSFHEP00000027656	Interleukin 6 receptor.	Uncharacterized protein.	0.725
LOC105928499	LOC105937903	ENSFHEP00000017587	ENSFHEP00000027656	Uncharacterized protein.	Uncharacterized protein.	0.725
LOC105937903	LOC105928473	ENSFHEP00000027656	ENSFHEP00000017376	Uncharacterized protein.	Interleukin 6 receptor.	0.725
LOC105937903	LOC105928499	ENSFHEP00000027656	ENSFHEP00000017587	Uncharacterized protein.	Uncharacterized protein.	0.725
batf	tbx21	ENSFHEP00000000603	ENSFHEP00000005131	Basic leucine zipper transcription factor, ATF-like.	T-box transcription factor 21.	0.417
hlx	tbx21	ENSFHEP00000034971	ENSFHEP00000005131	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.586
mtor	EIF2AK4	ENSFHEP00000010587	ENSFHEP00000029640	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.921
mtor	LOC105919467	ENSFHEP00000010587	ENSFHEP00000007990	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	TSC complex subunit 1.	0.935
mtor	LOC105927446	ENSFHEP00000010587	ENSFHEP00000013621	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	TSC complex subunit 1b.	0.935
rc3h1	rc3h2	ENSFHEP00000032263	ENSFHEP00000028276	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.793
rc3h2	rc3h1	ENSFHEP00000028276	ENSFHEP00000032263	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.793