STRINGSTRING
LOC105935861 LOC105935861 LOC105922446 LOC105922446 LOC105920966 LOC105920966 bmp15 bmp15 LOC105930794 LOC105930794 appl1 appl1 LOC105930774 LOC105930774 LOC105935333 LOC105935333 LOC105917364 LOC105917364 smpd3 smpd3 LOC105933644 LOC105933644 LOC105939866 LOC105939866 LOC105927928 LOC105927928 bmp5 bmp5 ACVR1C ACVR1C ACVR1 ACVR1 ENSFHEP00000034755 ENSFHEP00000034755 LOC105921341 LOC105921341 nlk nlk ENSFHEP00000033245 ENSFHEP00000033245 LOC105928914 LOC105928914 TGFB3 TGFB3 smad9 smad9 ENSFHEP00000000693 ENSFHEP00000000693 LOC105940274 LOC105940274 rgma rgma LOC105934063 LOC105934063 LOC105918991 LOC105918991 LOC105918990 LOC105918990 inppl1 inppl1 LOC105915546 LOC105915546 LOC105936361 LOC105936361 ENSFHEP00000002273 ENSFHEP00000002273 LOC105923386 LOC105923386 LOC105932304 LOC105932304 LOC105915540 LOC105915540 ENSFHEP00000002660 ENSFHEP00000002660 LOC105915527 LOC105915527 pxn pxn ENSFHEP00000002908 ENSFHEP00000002908 msx1 msx1 LOC105938663 LOC105938663 LOC105918450 LOC105918450 LOC105920199 LOC105920199 smad2 smad2 LOC105919548 LOC105919548 LOC105938719 LOC105938719 gdf15 gdf15 LOC105925994 LOC105925994 LOC105939150 LOC105939150 LOC105935574 LOC105935574 LOC105919514 LOC105919514 LOC105939100 LOC105939100 smad1 smad1 LOC105937995 LOC105937995 TMEM100 TMEM100 ENSFHEP00000008065 ENSFHEP00000008065 sostdc1 sostdc1 usp9x usp9x TGFBR2 TGFBR2 LOC105920636 LOC105920636 LOC105931003 LOC105931003 smurf1 smurf1 LOC105916514 LOC105916514 rgmb rgmb LOC105929913 LOC105929913 LOC105933301 LOC105933301 ENSFHEP00000010436 ENSFHEP00000010436 nodal nodal LOC105938966 LOC105938966 LOC105920529 LOC105920529 pdcd4 pdcd4 ENSFHEP00000012545 ENSFHEP00000012545 ski ski ENSFHEP00000013026 ENSFHEP00000013026 gdf3 gdf3 LOC105920438 LOC105920438 LOC105922368 LOC105922368 FAM83G FAM83G bmpr1b bmpr1b INHBC INHBC ENSFHEP00000015248 ENSFHEP00000015248 SMURF2 SMURF2 inha inha LOC105930843 LOC105930843 gdf10 gdf10 hpgd hpgd tgfb3 tgfb3 LOC105922275 LOC105922275 LOC105920991 LOC105920991 LOC105933693 LOC105933693 cited1 cited1 bmp4 bmp4 JADE2 JADE2 bmp2 bmp2 LOC105930802 LOC105930802 LOC105939356 LOC105939356 ventx ventx ccdc142 ccdc142 LOC105933078 LOC105933078 smad6 smad6 LOC105919134 LOC105919134 LOC105917338 LOC105917338 lpxn lpxn LOC105919700 LOC105919700 LOC105936994 LOC105936994 lrrc32 lrrc32 slc33a1 slc33a1 LOC105925564 LOC105925564 ENSFHEP00000021147 ENSFHEP00000021147 ACVR1B ACVR1B LOC105928977 LOC105928977 TBX2 TBX2 appl2 appl2 amh amh sfrp2 sfrp2 LOC105936367 LOC105936367 gdf5 gdf5 fut8 fut8 acvr2b acvr2b smad7 smad7 acvr2a acvr2a LOC105924100 LOC105924100 ENSFHEP00000023885 ENSFHEP00000023885 itgb6 itgb6 ENSFHEP00000024203 ENSFHEP00000024203 lef1 lef1 LOC105920743 LOC105920743 sirt1 sirt1 bmpr2 bmpr2 bmp8a bmp8a LOC105919484 LOC105919484 LOC105939051 LOC105939051 ENSFHEP00000026200 ENSFHEP00000026200 gdf6 gdf6 ENSFHEP00000026343 ENSFHEP00000026343 glg1 glg1 TGFB1I1 TGFB1I1 LOC105921852 LOC105921852 tgfbr3 tgfbr3 bmp3 bmp3 itgb8 itgb8 yap1 yap1 zyx zyx hivep1 hivep1 LOC105923080 LOC105923080 ENSFHEP00000029923 ENSFHEP00000029923 flcn flcn LOC105926907 LOC105926907 ppm1l ppm1l bmpr1a bmpr1a LOC105930844 LOC105930844 ENSFHEP00000032031 ENSFHEP00000032031 ENSFHEP00000032057 ENSFHEP00000032057 LOC105935930 LOC105935930
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105935861Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (498 aa)
LOC105922446Inhibitor of DNA binding 1, HLH protein. (127 aa)
LOC105920966Myostatin a. (362 aa)
bmp15Bone morphogenetic protein 15. (440 aa)
LOC105930794Bone morphogenetic protein 10, like. (458 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (650 aa)
LOC105930774Mothers against decapentaplegic homolog. (393 aa)
LOC105935333Negative regulator of reactive oxygen species. (681 aa)
LOC105917364AMOP domain-containing protein. (445 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (706 aa)
LOC105933644Polyadenylate-binding protein 1. (559 aa)
LOC105939866Programmed cell death 4a. (467 aa)
LOC105927928Mothers against decapentaplegic homolog. (425 aa)
bmp5Bone morphogenetic protein 5. (465 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (487 aa)
ENSFHEP00000034755MH1 domain-containing protein. (154 aa)
LOC105921341MH2 domain-containing protein. (222 aa)
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa)
ENSFHEP00000033245Activin_recp domain-containing protein. (189 aa)
LOC105928914Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (324 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
smad9Mothers against decapentaplegic homolog. (467 aa)
ENSFHEP00000000693Uncharacterized protein. (260 aa)
LOC105940274Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (673 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (445 aa)
LOC105934063FAM83 domain-containing protein. (839 aa)
LOC105918991BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC105918990BMP and activin membrane-bound inhibitor homolog. (256 aa)
inppl1Inositol polyphosphate phosphatase-like 1a. (1250 aa)
LOC105915546Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
LOC105936361Mothers against decapentaplegic homolog. (427 aa)
ENSFHEP00000002273PDZ domain-containing protein. (156 aa)
LOC105923386Secreted frizzled-related protein 2 like. (342 aa)
LOC105932304Bone morphogenetic protein 7b. (427 aa)
LOC105915540Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (732 aa)
ENSFHEP00000002660Uncharacterized protein. (252 aa)
LOC105915527Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
pxnPaxillin, putative. (1179 aa)
ENSFHEP00000002908TPR_REGION domain-containing protein. (142 aa)
msx1Muscle segment homeobox 1a. (281 aa)
LOC105938663TGF_BETA_2 domain-containing protein. (456 aa)
LOC105918450Teratocarcinoma-derived growth factor 1. (202 aa)
LOC105920199TGF_BETA_2 domain-containing protein. (446 aa)
smad2Mothers against decapentaplegic homolog. (358 aa)
LOC105919548Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
LOC105938719Mothers against decapentaplegic homolog. (467 aa)
gdf15Bone morphogenetic protein 6. (373 aa)
LOC105925994Bone morphogenetic protein 7a. (393 aa)
LOC105939150Bone morphogenetic protein 16. (476 aa)
LOC105935574Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
LOC105919514EGF-like domain-containing protein. (216 aa)
LOC105939100Growth differentiation factor 11. (356 aa)
smad1Mothers against decapentaplegic homolog. (488 aa)
LOC105937995Spartin b. (576 aa)
TMEM100Transmembrane protein 100. (144 aa)
ENSFHEP00000008065Uncharacterized protein. (637 aa)
sostdc1Sclerostin domain containing 1a. (220 aa)
usp9xUbiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2536 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
LOC105920636Uncharacterized protein. (362 aa)
LOC105931003Anti-dorsalizing morphogenic protein. (380 aa)
smurf1E3 ubiquitin-protein ligase. (729 aa)
LOC105916514Myostatin b. (420 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (472 aa)
LOC105929913E3 ubiquitin-protein ligase. (770 aa)
LOC105933301Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (718 aa)
ENSFHEP00000010436TGF_BETA_2 domain-containing protein. (114 aa)
nodalNodal-related 2. (379 aa)
LOC105938966RGM domain family, member D. (458 aa)
LOC105920529Mothers against decapentaplegic homolog. (520 aa)
pdcd4Programmed cell death protein 4. (488 aa)
ENSFHEP00000012545UPAR/Ly6 domain-containing protein. (160 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (726 aa)
ENSFHEP00000013026JunE proto-oncogene, AP-1 transcription factor subunit. (334 aa)
gdf3Growth differentiation factor 3. (405 aa)
LOC105920438Transforming growth factor beta; Belongs to the TGF-beta family. (418 aa)
LOC105922368Inhibin subunit beta Ab. (396 aa)
FAM83GFAM83 domain-containing protein. (502 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
INHBCInhibin subunit beta C. (383 aa)
ENSFHEP00000015248Uncharacterized protein. (235 aa)
SMURF2E3 ubiquitin-protein ligase. (785 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (350 aa)
LOC105930843Growth differentiation factor 2. (422 aa)
gdf10Growth differentiation factor 10b. (449 aa)
hpgd15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
LOC105922275Inhibin subunit beta B. (394 aa)
LOC105920991Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
LOC105933693V-ski avian sarcoma viral oncogene homolog b. (676 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (149 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
JADE2Jade family PHD finger 2. (906 aa)
bmp2Bone morphogenetic protein 2b. (419 aa)
LOC105930802Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
LOC105939356Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa)
ventxVentral homeobox. (250 aa)
ccdc142Uncharacterized protein. (893 aa)
LOC105933078Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
smad6Mothers against decapentaplegic homolog. (492 aa)
LOC105919134Hemojuvelin BMP co-receptor. (401 aa)
LOC105917338Paxillin b. (1179 aa)
lpxnLeupaxin. (337 aa)
LOC105919700Peptidylprolyl isomerase. (407 aa)
LOC105936994Left-right determination factor. (358 aa)
lrrc32Leucine rich repeat containing 32. (697 aa)
slc33a1Solute carrier family 33 member 1. (550 aa)
LOC105925564RNA binding motif protein 4.3. (349 aa)
ENSFHEP00000021147Uncharacterized protein. (319 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
LOC105928977Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
TBX2T-box transcription factor 2. (686 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
amhAnti-Mullerian hormone. (492 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LOC105936367Mothers against decapentaplegic homolog. (503 aa)
gdf5Growth differentiation factor 5. (487 aa)
fut8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (583 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
smad7Mothers against decapentaplegic homolog. (378 aa)
acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
LOC105924100Uncharacterized protein. (585 aa)
ENSFHEP00000023885Muscle segment homeobox 3. (247 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (1042 aa)
ENSFHEP00000024203MH1 domain-containing protein. (95 aa)
lef1Lymphoid enhancer-binding factor 1. (424 aa)
LOC105920743Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (317 aa)
sirt1Sirtuin 1. (719 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1050 aa)
bmp8aBone morphogenetic protein 8a. (435 aa)
LOC105919484Mothers against decapentaplegic homolog. (412 aa)
LOC105939051Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
ENSFHEP00000026200TGF-beta activated kinase 1/MAP3K7 binding protein 1. (436 aa)
gdf6Growth differentiation factor 6a. (414 aa)
ENSFHEP00000026343SKI-like proto-oncogene a. (264 aa)
glg1Golgi glycoprotein 1b. (994 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (483 aa)
LOC105921852TGFb_propeptide domain-containing protein. (373 aa)
tgfbr3Transforming growth factor, beta receptor III. (834 aa)
bmp3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (463 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (760 aa)
yap1Yes-associated protein 1. (429 aa)
zyxZyxin. (547 aa)
hivep1Human immunodeficiency virus type I enhancer binding protein 1. (2541 aa)
LOC105923080Uncharacterized protein. (321 aa)
ENSFHEP00000029923MH2 domain-containing protein. (196 aa)
flcnFolliculin. (564 aa)
LOC105926907Southpaw. (409 aa)
ppm1lPPM-type phosphatase domain-containing protein. (371 aa)
bmpr1aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
LOC105930844TGF_BETA_2 domain-containing protein. (390 aa)
ENSFHEP00000032031Uncharacterized protein. (1446 aa)
ENSFHEP00000032057Uncharacterized protein. (959 aa)
LOC105935930Protein phosphatase, Mg2+/Mn2+ dependent, 1La. (363 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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