STRINGSTRING
pfas pfas ENSFHEP00000000427 ENSFHEP00000000427 ppat ppat dut dut ampd3 ampd3 LOC105936234 LOC105936234 LOC105927134 LOC105927134 impdh1 impdh1 LOC105918498 LOC105918498 LOC105938694 LOC105938694 uckl1 uckl1 UCKL1 UCKL1 nudt2 nudt2 LOC105935754 LOC105935754 ENSFHEP00000003316 ENSFHEP00000003316 ENSFHEP00000003320 ENSFHEP00000003320 LOC110366376 LOC110366376 ampd2 ampd2 LOC105916688 LOC105916688 LOC105932207 LOC105932207 adsl adsl cda cda ENSFHEP00000008042 ENSFHEP00000008042 atic atic LOC105940084 LOC105940084 tk2 tk2 aprt aprt tyms tyms uprt uprt rfk rfk LOC105915950 LOC105915950 ada ada hprt1 hprt1 ENSFHEP00000014655 ENSFHEP00000014655 LOC105926333 LOC105926333 LOC105927006 LOC105927006 LOC105929791 LOC105929791 impdh2 impdh2 LOC105917431 LOC105917431 tk1 tk1 dck dck LOC105938211 LOC105938211 upp2 upp2 gmps gmps dhodh dhodh LOC105927949 LOC105927949 LOC105926233 LOC105926233 gart gart LOC105924867 LOC105924867 LOC105925294 LOC105925294 LOC105916994 LOC105916994 ADK ADK ampd1 ampd1 adss1 adss1 uck1 uck1 LOC105936968 LOC105936968
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfasPhosphoribosylformylglycinamidine synthase. (1318 aa)
ENSFHEP00000000427AIRC domain-containing protein. (424 aa)
ppatAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (502 aa)
dutDeoxyuridine triphosphatase. (197 aa)
ampd3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (793 aa)
LOC105936234Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (427 aa)
LOC105927134AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (666 aa)
impdh1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (541 aa)
LOC105918498dNK domain-containing protein. (266 aa)
LOC105938694Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (517 aa)
uckl1Uridine-cytidine kinase; Belongs to the uridine kinase family. (548 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (516 aa)
nudt2Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (147 aa)
LOC105935754Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa)
ENSFHEP00000003316Uncharacterized protein. (88 aa)
ENSFHEP00000003320Uncharacterized protein. (66 aa)
LOC110366376Adenine phosphoribosyltransferase. (493 aa)
ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (765 aa)
LOC105916688Phosphoribosyltransferase domain-containing protein 1. (164 aa)
LOC105932207Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (473 aa)
adslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
cdaCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (150 aa)
ENSFHEP00000008042dUTPase domain-containing protein. (147 aa)
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (628 aa)
LOC105940084Si:ch211-243j20.2. (542 aa)
tk2Thymidine kinase 2. (262 aa)
aprtAdenine phosphoribosyltransferase. (181 aa)
tymsThymidylate synthetase. (327 aa)
uprtUracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). (268 aa)
rfkRiboflavin kinase. (169 aa)
LOC105915950Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
adaAdenosine deaminase. (397 aa)
hprt1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
ENSFHEP00000014655dUTPase domain-containing protein. (178 aa)
LOC105926333Uridine phosphorylase 1. (312 aa)
LOC105927006Deoxyguanosine kinase. (309 aa)
LOC105929791Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (136 aa)
impdh2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
LOC105917431Pribosyltran_N domain-containing protein. (318 aa)
tk1Thymidine kinase. (236 aa)
dckDeoxycytidine kinase. (263 aa)
LOC105938211Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (215 aa)
upp2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (283 aa)
gmpsGMP synthase (Glutamine-hydrolyzing). (690 aa)
dhodhDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (430 aa)
LOC105927949Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (429 aa)
LOC105926233AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (773 aa)
gartTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1014 aa)
LOC105924867Phosphoribosyl pyrophosphate synthetase 1B. (318 aa)
LOC105925294Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
LOC105916994Zgc:174895. (200 aa)
ADKAdenosine kinase. (357 aa)
ampd1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (737 aa)
adss1Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (467 aa)
uck1Uridine-cytidine kinase; Belongs to the uridine kinase family. (272 aa)
LOC105936968Adenosine kinase a. (387 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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