(18 nodes) Positive regulation of phosphatase activity network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000032057	Uncharacterized protein. (959 aa)
	plek	Pleckstrin. (373 aa)
	ENSFHEP00000002273	PDZ domain-containing protein. (156 aa)
	ptpa	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (322 aa)
	LOC105935574	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
	LOC105920636	Uncharacterized protein. (362 aa)
	vrk3	Inactive serine/threonine-protein kinase VRK3. (517 aa)
	LOC105915343	Calcineurin-like EF-hand protein 2. (194 aa)
	LOC105929179	Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	mtmr9	Myotubularin related protein 9. (549 aa)
	LOC105926275	Protein phosphatase 1, regulatory subunit 15B. (553 aa)
	pawr	PRKC apoptosis WT1 regulator protein. (337 aa)
	LOC105938713	Receptor-interacting serine-threonine kinase 3. (436 aa)
	LOC105917785	Phosphatase 1 regulatory subunit 15B. (599 aa)
	LOC105925917	Myotubularin-related protein 9. (548 aa)
	ppargc1b	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (927 aa)
	LOC105919183	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (498 aa)
	ptprc	Uncharacterized protein. (989 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000002273	ENSFHEP00000032057	ENSFHEP00000002273	ENSFHEP00000032057	PDZ domain-containing protein.	Uncharacterized protein.	0.560
ENSFHEP00000002273	LOC105920636	ENSFHEP00000002273	ENSFHEP00000008931	PDZ domain-containing protein.	Uncharacterized protein.	0.586
ENSFHEP00000032057	ENSFHEP00000002273	ENSFHEP00000032057	ENSFHEP00000002273	Uncharacterized protein.	PDZ domain-containing protein.	0.560
LOC105919183	LOC105938713	ENSFHEP00000033309	ENSFHEP00000022143	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	Receptor-interacting serine-threonine kinase 3.	0.766
LOC105920636	ENSFHEP00000002273	ENSFHEP00000008931	ENSFHEP00000002273	Uncharacterized protein.	PDZ domain-containing protein.	0.586
LOC105938713	LOC105919183	ENSFHEP00000022143	ENSFHEP00000033309	Receptor-interacting serine-threonine kinase 3.	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	0.766
plek	ptprc	ENSFHEP00000001171	ENSFHEP00000034551	Pleckstrin.	Uncharacterized protein.	0.456
ptprc	plek	ENSFHEP00000034551	ENSFHEP00000001171	Uncharacterized protein.	Pleckstrin.	0.456