(12 nodes) Superoxide-generating NADPH oxidase activator activity network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sh3pxd2a	Uncharacterized protein. (1095 aa)
	ncf1	Neutrophil cytosolic factor 1. (411 aa)
	LOC105915406	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (561 aa)
	sh3pxd2b	SH3 and PX domains 2B. (935 aa)
	ENSFHEP00000013024	Uncharacterized protein. (277 aa)
	noxo1	NADPH oxidase organizer 1a. (518 aa)
	LOC105920839	NADPH oxidase activator 1. (543 aa)
	LOC105933547	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (523 aa)
	ncf4	Neutrophil cytosolic factor 4. (350 aa)
	LOC105929413	NADPH oxidase organizer 1b. (483 aa)
	ENSFHEP00000033804	Neutrophil cytosolic factor 2. (377 aa)
	LOC105923660	SH3 and PX domains 2Aa. (715 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000013024	ENSFHEP00000033804	ENSFHEP00000013024	ENSFHEP00000033804	Uncharacterized protein.	Neutrophil cytosolic factor 2.	0.633
ENSFHEP00000013024	LOC105920839	ENSFHEP00000013024	ENSFHEP00000023861	Uncharacterized protein.	NADPH oxidase activator 1.	0.633
ENSFHEP00000013024	LOC105923660	ENSFHEP00000013024	ENSFHEP00000035018	Uncharacterized protein.	SH3 and PX domains 2Aa.	0.899
ENSFHEP00000033804	ENSFHEP00000013024	ENSFHEP00000033804	ENSFHEP00000013024	Neutrophil cytosolic factor 2.	Uncharacterized protein.	0.633
ENSFHEP00000033804	LOC105920839	ENSFHEP00000033804	ENSFHEP00000023861	Neutrophil cytosolic factor 2.	NADPH oxidase activator 1.	0.413
ENSFHEP00000033804	LOC105923660	ENSFHEP00000033804	ENSFHEP00000035018	Neutrophil cytosolic factor 2.	SH3 and PX domains 2Aa.	0.633
ENSFHEP00000033804	LOC105929413	ENSFHEP00000033804	ENSFHEP00000030539	Neutrophil cytosolic factor 2.	NADPH oxidase organizer 1b.	0.824
ENSFHEP00000033804	ncf1	ENSFHEP00000033804	ENSFHEP00000005275	Neutrophil cytosolic factor 2.	Neutrophil cytosolic factor 1.	0.984
ENSFHEP00000033804	ncf4	ENSFHEP00000033804	ENSFHEP00000027111	Neutrophil cytosolic factor 2.	Neutrophil cytosolic factor 4.	0.990
ENSFHEP00000033804	noxo1	ENSFHEP00000033804	ENSFHEP00000022142	Neutrophil cytosolic factor 2.	NADPH oxidase organizer 1a.	0.824
ENSFHEP00000033804	sh3pxd2a	ENSFHEP00000033804	ENSFHEP00000001451	Neutrophil cytosolic factor 2.	Uncharacterized protein.	0.633
ENSFHEP00000033804	sh3pxd2b	ENSFHEP00000033804	ENSFHEP00000012911	Neutrophil cytosolic factor 2.	SH3 and PX domains 2B.	0.633
LOC105920839	ENSFHEP00000013024	ENSFHEP00000023861	ENSFHEP00000013024	NADPH oxidase activator 1.	Uncharacterized protein.	0.633
LOC105920839	ENSFHEP00000033804	ENSFHEP00000023861	ENSFHEP00000033804	NADPH oxidase activator 1.	Neutrophil cytosolic factor 2.	0.413
LOC105920839	LOC105923660	ENSFHEP00000023861	ENSFHEP00000035018	NADPH oxidase activator 1.	SH3 and PX domains 2Aa.	0.633
LOC105920839	LOC105929413	ENSFHEP00000023861	ENSFHEP00000030539	NADPH oxidase activator 1.	NADPH oxidase organizer 1b.	0.849
LOC105920839	ncf1	ENSFHEP00000023861	ENSFHEP00000005275	NADPH oxidase activator 1.	Neutrophil cytosolic factor 1.	0.981
LOC105920839	ncf4	ENSFHEP00000023861	ENSFHEP00000027111	NADPH oxidase activator 1.	Neutrophil cytosolic factor 4.	0.987
LOC105920839	noxo1	ENSFHEP00000023861	ENSFHEP00000022142	NADPH oxidase activator 1.	NADPH oxidase organizer 1a.	0.849
LOC105920839	sh3pxd2a	ENSFHEP00000023861	ENSFHEP00000001451	NADPH oxidase activator 1.	Uncharacterized protein.	0.633