70 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	wdr24	WD repeat domain 24. (706 aa)
	phf23	PHD finger protein 23b. (316 aa)
	LOC105933038	Tectonin beta-propeller repeat containing 1b. (1181 aa)
	pip4k2a	Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (443 aa)
	lrsam1	Leucine rich repeat and sterile alpha motif containing 1. (734 aa)
	fez1	Fasciculation and elongation protein zeta 1 (zygin I). (406 aa)
	hspb8	Heat shock protein b8; Belongs to the small heat shock protein (HSP20) family. (221 aa)
	SNX4	Sorting nexin 4. (350 aa)
	LOC105937290	Short coiled-coil protein. (104 aa)
	pink1	PTEN induced kinase 1. (585 aa)
	sptlc1	Serine palmitoyltransferase, long chain base subunit 1. (251 aa)
	vps13d	Vacuolar protein sorting 13 homolog D. (3545 aa)
	LOC105931776	Sorting nexin 4. (418 aa)
	LOC105930548	Si:ch211-57i17.1. (398 aa)
	LOC105919467	TSC complex subunit 1. (1034 aa)
	smg1	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3488 aa)
	tsc2	TSC complex subunit 2. (1700 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
	PIP4K2B	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (413 aa)
	nod2	Nucleotide-binding oligomerization domain containing 2. (1000 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
	ENSFHEP00000010671	GOLD domain-containing protein. (158 aa)
	wdr45	WD repeat domain 45. (358 aa)
	atp13a2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1165 aa)
	LOC105917598	Sorting nexin 7. (380 aa)
	snx30	Sorting nexin family member 30. (400 aa)
	scoc	Short coiled-coil protein a. (80 aa)
	LOC105936058	Uncharacterized protein. (332 aa)
	htt	Huntingtin. (3077 aa)
	LOC105917531	Si:dkey-288i20.2. (397 aa)
	LOC105927446	TSC complex subunit 1b. (1254 aa)
	atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (118 aa)
	sting1	Stimulator of interferon genes protein. (400 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (576 aa)
	LOC105926784	Leucine zipper tumor suppressor 1, putative. (633 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (769 aa)
	LOC105919205	Nuclear receptor binding protein 2b. (512 aa)
	bnip3	BCL2 interacting protein 3. (204 aa)
	LOC105933104	Forkhead box A3. (463 aa)
	ENSFHEP00000018558	Protein kinase domain-containing protein. (516 aa)
	LOC105924518	FYVE and coiled-coil domain containing 1b. (908 aa)
	fyco1	FYVE and coiled-coil domain containing 1a. (1510 aa)
	sesn1	Sestrin 1. (548 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (343 aa)
	tbc1d25	TBC1 domain family, member 25. (855 aa)
	cln3	Battenin. (439 aa)
	gpsm1	G protein signaling modulator 1b. (662 aa)
	rnf31	Ring finger protein 31. (987 aa)
	clec16a	C-type lectin domain containing 16A. (935 aa)
	LOC105939748	Zgc:100846. (441 aa)
	dcn	Decorin; May affect the rate of fibrils formation. (362 aa)
	calcoco2	Calcium binding and coiled-coil domain 2. (598 aa)
	atg14	Autophagy related 14. (508 aa)
	LOC105929979	Zgc:73226. (181 aa)
	sirt1	Sirtuin 1. (719 aa)
	LOC105925555	Sestrin 2. (558 aa)
	nod1	Nucleotide-binding oligomerization domain containing 1. (941 aa)
	ENSFHEP00000025475	WW domain-containing protein. (184 aa)
	ENSFHEP00000025525	Uncharacterized protein. (107 aa)
	rab3gap2	RAB3 GTPase activating protein subunit 2 (non-catalytic). (1369 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (312 aa)
	ENSFHEP00000026420	Nuclear protein 1a. (76 aa)
	tmem39a	Transmembrane protein 39A. (493 aa)
	LOC105925715	Si:zfos-80g12.1. (371 aa)
	tmem39b	Transmembrane protein 39B. (488 aa)
	LOC105924849	Serine palmitoyltransferase, long chain base subunit 1. (230 aa)
	LOC105924834	RUN domain-containing protein. (983 aa)
	ENSFHEP00000033314	ANK_REP_REGION domain-containing protein. (762 aa)
	pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1334 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000010671	LOC105924518	ENSFHEP00000010671	ENSFHEP00000020415	GOLD domain-containing protein.	FYVE and coiled-coil domain containing 1b.	0.899
ENSFHEP00000010671	LOC105924834	ENSFHEP00000010671	ENSFHEP00000032250	GOLD domain-containing protein.	RUN domain-containing protein.	0.899
ENSFHEP00000010671	fyco1	ENSFHEP00000010671	ENSFHEP00000020880	GOLD domain-containing protein.	FYVE and coiled-coil domain containing 1a.	0.899
ENSFHEP00000010671	pik3c3	ENSFHEP00000010671	ENSFHEP00000009644	GOLD domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.440
ENSFHEP00000018558	ENSFHEP00000033314	ENSFHEP00000018558	ENSFHEP00000033314	Protein kinase domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.942
ENSFHEP00000018558	pink1	ENSFHEP00000018558	ENSFHEP00000006364	Protein kinase domain-containing protein.	PTEN induced kinase 1.	0.416
ENSFHEP00000025475	LOC105919467	ENSFHEP00000025475	ENSFHEP00000007990	WW domain-containing protein.	TSC complex subunit 1.	0.489
ENSFHEP00000025475	LOC105927446	ENSFHEP00000025475	ENSFHEP00000013621	WW domain-containing protein.	TSC complex subunit 1b.	0.489
ENSFHEP00000025475	hspb8	ENSFHEP00000025475	ENSFHEP00000004182	WW domain-containing protein.	Heat shock protein b8; Belongs to the small heat shock protein (HSP20) family.	0.935
ENSFHEP00000025525	PIP4K2B	ENSFHEP00000025525	ENSFHEP00000009683	Uncharacterized protein.	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.	0.449
ENSFHEP00000025525	pip4k2a	ENSFHEP00000025525	ENSFHEP00000002724	Uncharacterized protein.	Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a.	0.449
ENSFHEP00000033314	ENSFHEP00000018558	ENSFHEP00000033314	ENSFHEP00000018558	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.942
ENSFHEP00000033314	atp13a2	ENSFHEP00000033314	ENSFHEP00000011077	ANK_REP_REGION domain-containing protein.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.538
ENSFHEP00000033314	pink1	ENSFHEP00000033314	ENSFHEP00000006364	ANK_REP_REGION domain-containing protein.	PTEN induced kinase 1.	0.416
LOC105917531	LOC105937290	ENSFHEP00000013429	ENSFHEP00000005919	Si:dkey-288i20.2.	Short coiled-coil protein.	0.717
LOC105917531	scoc	ENSFHEP00000013429	ENSFHEP00000011964	Si:dkey-288i20.2.	Short coiled-coil protein a.	0.717
LOC105917598	LOC105931776	ENSFHEP00000011265	ENSFHEP00000007181	Sorting nexin 7.	Sorting nexin 4.	0.946
LOC105917598	SNX4	ENSFHEP00000011265	ENSFHEP00000004756	Sorting nexin 7.	Sorting nexin 4.	0.945
LOC105917598	atg12	ENSFHEP00000011265	ENSFHEP00000014275	Sorting nexin 7.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.462
LOC105917598	atg5	ENSFHEP00000011265	ENSFHEP00000026190	Sorting nexin 7.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.438