(71 nodes) Nuclear matrix network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105935255	RAD21 cohesin complex component like 1. (544 aa)
	ENSFHEP00000001801	Bloom syndrome, RecQ helicase. (1405 aa)
	LOC105915562	C2H2-type domain-containing protein. (588 aa)
	LOC105932309	AXH domain-containing protein. (679 aa)
	ogg1	8-oxoguanine DNA glycosylase. (393 aa)
	rad21	RAD21 cohesin complex component a. (639 aa)
	pola1	DNA polymerase. (1507 aa)
	cfl2	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
	LOC105935293	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1439 aa)
	snw1	SNW domain containing 1. (544 aa)
	LOC105938178	Zinc finger protein 703. (577 aa)
	hnrnpm	Heterogeneous nuclear ribonucleoprotein M. (699 aa)
	LOC105931713	Keratin 4; Belongs to the intermediate filament family. (454 aa)
	DGKQ	Diacylglycerol kinase. (783 aa)
	ENSFHEP00000006032	RRM domain-containing protein. (136 aa)
	LOC105931712	Keratin 4; Belongs to the intermediate filament family. (499 aa)
	LOC105937166	PRP40 pre-mRNA processing factor 40 homolog A. (764 aa)
	maea	Macrophage erythroblast attacher. (396 aa)
	satb1	DNA-binding protein SATB1. (872 aa)
	HLCS	Holocarboxylase synthetase. (740 aa)
	thoc1	THO complex subunit 1. (654 aa)
	ENSFHEP00000008058	Uncharacterized protein. (215 aa)
	xpot	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (784 aa)
	LOC105932114	NMDA receptor synaptonuclear signaling and neuronal migration factor a. (477 aa)
	ENSFHEP00000011286	Prohibitin. (104 aa)
	phf5a	PHD finger protein 5A. (110 aa)
	smc3	Structural maintenance of chromosomes 3. (1155 aa)
	satb2	DNA-binding protein SATB. (780 aa)
	LOC105929153	Teneurin transmembrane protein 1. (2617 aa)
	GFI1	Growth factor independent 1 transcriptional repressor. (400 aa)
	ENSFHEP00000013092	Uncharacterized protein. (137 aa)
	hat1	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (408 aa)
	gfi1b	Growth factor independent 1B transcription repressor. (328 aa)
	cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (167 aa)
	ercc8	Excision repair cross-complementation group 8. (367 aa)
	LOC105934236	IF rod domain-containing protein; Belongs to the intermediate filament family. (508 aa)
	LOC105926380	Ataxin 1b. (827 aa)
	LOC105933211	Proteasome subunit alpha type. (257 aa)
	LOC105919253	CXXC finger protein 1a. (550 aa)
	ENSFHEP00000016371	Prohibitin. (200 aa)
	atxn1	Ataxin 1a. (796 aa)
	cxxc1	CXXC finger protein 1b. (540 aa)
	LOC105938216	DUF3736 domain-containing protein. (1153 aa)
	gse1	Gse1 coiled-coil protein. (2124 aa)
	nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor b. (563 aa)
	men1	Multiple endocrine neoplasia I. (625 aa)
	ENSFHEP00000020981	TROVE domain-containing protein. (1243 aa)
	DCAF7	DDB1 and CUL4 associated factor 7. (342 aa)
	ENSFHEP00000022405	Zinc finger protein Gfi-1b. (321 aa)
	numa1	Uncharacterized protein. (2321 aa)
	LOC105930638	Proteasome subunit alpha type. (246 aa)
	LOC105935283	CCAAT enhancer binding protein beta. (288 aa)
	ENSFHEP00000024458	Uncharacterized protein. (375 aa)
	LOC105931738	Zgc:158846; Belongs to the intermediate filament family. (527 aa)
	ENSFHEP00000025064	RRM domain-containing protein. (134 aa)
	nufip1	C2H2-type domain-containing protein. (539 aa)
	LOC105931684	RAD21 cohesin complex component b. (592 aa)
	chmp1a	Charged multivesicular body protein 1A. (199 aa)
	kin	Kin17 DNA and RNA binding protein. (460 aa)
	ENSFHEP00000026714	Non-POU domain containing, octamer-binding. (429 aa)
	LOC105938982	Centromere protein F, 350/400kDa (Mitosin). (2788 aa)
	CASK	Uncharacterized protein; Belongs to the MAGUK family. (897 aa)
	gfi1	Growth factor independent 1A transcription repressor b. (388 aa)
	morc2	MORC family CW-type zinc finger 2. (1017 aa)
	sfpq	Splicing factor proline/glutamine-rich. (744 aa)
	LOC105934238	Keratin 8; Belongs to the intermediate filament family. (528 aa)
	ENSFHEP00000031741	Keratin 8; Belongs to the intermediate filament family. (420 aa)
	ahctf1	AT hook containing transcription factor 1. (2168 aa)
	LOC105921523	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (960 aa)
	psma6	Proteasome subunit alpha type. (246 aa)
	fign	Fidgetin; Belongs to the AAA ATPase family. (751 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASK	LOC105921523	ENSFHEP00000027213	ENSFHEP00000032900	Uncharacterized protein; Belongs to the MAGUK family.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.810
CASK	LOC105937166	ENSFHEP00000027213	ENSFHEP00000006506	Uncharacterized protein; Belongs to the MAGUK family.	PRP40 pre-mRNA processing factor 40 homolog A.	0.583
DCAF7	ENSFHEP00000020981	ENSFHEP00000021275	ENSFHEP00000020981	DDB1 and CUL4 associated factor 7.	TROVE domain-containing protein.	0.615
DCAF7	ercc8	ENSFHEP00000021275	ENSFHEP00000015379	DDB1 and CUL4 associated factor 7.	Excision repair cross-complementation group 8.	0.815
ENSFHEP00000001801	ogg1	ENSFHEP00000001801	ENSFHEP00000002753	Bloom syndrome, RecQ helicase.	8-oxoguanine DNA glycosylase.	0.562
ENSFHEP00000001801	pola1	ENSFHEP00000001801	ENSFHEP00000003558	Bloom syndrome, RecQ helicase.	DNA polymerase.	0.728
ENSFHEP00000001801	smc3	ENSFHEP00000001801	ENSFHEP00000011475	Bloom syndrome, RecQ helicase.	Structural maintenance of chromosomes 3.	0.500
ENSFHEP00000006032	ENSFHEP00000024458	ENSFHEP00000006032	ENSFHEP00000024458	RRM domain-containing protein.	Uncharacterized protein.	0.426
ENSFHEP00000006032	hnrnpm	ENSFHEP00000006032	ENSFHEP00000005726	RRM domain-containing protein.	Heterogeneous nuclear ribonucleoprotein M.	0.559
ENSFHEP00000008058	ENSFHEP00000020981	ENSFHEP00000008058	ENSFHEP00000020981	Uncharacterized protein.	TROVE domain-containing protein.	0.615
ENSFHEP00000008058	ercc8	ENSFHEP00000008058	ENSFHEP00000015379	Uncharacterized protein.	Excision repair cross-complementation group 8.	0.815
ENSFHEP00000011286	ENSFHEP00000016371	ENSFHEP00000011286	ENSFHEP00000016371	Prohibitin.	Prohibitin.	0.925
ENSFHEP00000016371	ENSFHEP00000011286	ENSFHEP00000016371	ENSFHEP00000011286	Prohibitin.	Prohibitin.	0.925
ENSFHEP00000020981	DCAF7	ENSFHEP00000020981	ENSFHEP00000021275	TROVE domain-containing protein.	DDB1 and CUL4 associated factor 7.	0.615
ENSFHEP00000020981	ENSFHEP00000008058	ENSFHEP00000020981	ENSFHEP00000008058	TROVE domain-containing protein.	Uncharacterized protein.	0.615
ENSFHEP00000020981	LOC105938216	ENSFHEP00000020981	ENSFHEP00000018555	TROVE domain-containing protein.	DUF3736 domain-containing protein.	0.553
ENSFHEP00000020981	ercc8	ENSFHEP00000020981	ENSFHEP00000015379	TROVE domain-containing protein.	Excision repair cross-complementation group 8.	0.785
ENSFHEP00000020981	gse1	ENSFHEP00000020981	ENSFHEP00000019156	TROVE domain-containing protein.	Gse1 coiled-coil protein.	0.553
ENSFHEP00000020981	hnrnpm	ENSFHEP00000020981	ENSFHEP00000005726	TROVE domain-containing protein.	Heterogeneous nuclear ribonucleoprotein M.	0.475
ENSFHEP00000024458	ENSFHEP00000006032	ENSFHEP00000024458	ENSFHEP00000006032	Uncharacterized protein.	RRM domain-containing protein.	0.426