(20 nodes) Oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor network (Fundulus heteroclitus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	mthfd1	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
	ENSFHEP00000009699	Uncharacterized protein. (209 aa)
	crym	Crystallin, mu. (322 aa)
	LOC105928409	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (363 aa)
	qdpr	Quinoid dihydropteridine reductase a. (236 aa)
	LOC105933714	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
	mthfd2	Uncharacterized protein. (338 aa)
	tmed8	Transmembrane p24 trafficking protein 8. (274 aa)
	noxred1	NADP-dependent oxidoreductase domain-containing protein 1. (337 aa)
	LOC105917737	Zgc:153031. (200 aa)
	LOC105936185	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (321 aa)
	pycr3	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (273 aa)
	mthfr	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (681 aa)
	mthfd1l	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (974 aa)
	aass	Aminoadipate-semialdehyde synthase. (930 aa)
	blvrb	Biliverdin reductase B. (230 aa)
	LOC105915762	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (324 aa)
	aldh1l2	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (847 aa)
	ENSFHEP00000013747	Aldedh domain-containing protein. (163 aa)
	dhfr	Dihydrofolate reductase. (165 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000009699	ENSFHEP00000013747	ENSFHEP00000009699	ENSFHEP00000013747	Uncharacterized protein.	Aldedh domain-containing protein.	0.748
ENSFHEP00000009699	LOC105917737	ENSFHEP00000009699	ENSFHEP00000025955	Uncharacterized protein.	Zgc:153031.	0.828
ENSFHEP00000009699	LOC105928409	ENSFHEP00000009699	ENSFHEP00000004658	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.877
ENSFHEP00000009699	LOC105933714	ENSFHEP00000009699	ENSFHEP00000032018	Uncharacterized protein.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.784
ENSFHEP00000009699	aldh1l2	ENSFHEP00000009699	ENSFHEP00000013765	Uncharacterized protein.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.748
ENSFHEP00000009699	dhfr	ENSFHEP00000009699	ENSFHEP00000000250	Uncharacterized protein.	Dihydrofolate reductase.	0.838
ENSFHEP00000009699	mthfd1l	ENSFHEP00000009699	ENSFHEP00000021307	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.740
ENSFHEP00000009699	mthfd2	ENSFHEP00000009699	ENSFHEP00000031377	Uncharacterized protein.	Uncharacterized protein.	0.877
ENSFHEP00000009699	mthfr	ENSFHEP00000009699	ENSFHEP00000021448	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.870
ENSFHEP00000013747	ENSFHEP00000009699	ENSFHEP00000013747	ENSFHEP00000009699	Aldedh domain-containing protein.	Uncharacterized protein.	0.748
ENSFHEP00000013747	LOC105915762	ENSFHEP00000013747	ENSFHEP00000017061	Aldedh domain-containing protein.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.410
ENSFHEP00000013747	LOC105917737	ENSFHEP00000013747	ENSFHEP00000025955	Aldedh domain-containing protein.	Zgc:153031.	0.927
ENSFHEP00000013747	LOC105928409	ENSFHEP00000013747	ENSFHEP00000004658	Aldedh domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.919
ENSFHEP00000013747	LOC105933714	ENSFHEP00000013747	ENSFHEP00000032018	Aldedh domain-containing protein.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.898
ENSFHEP00000013747	LOC105936185	ENSFHEP00000013747	ENSFHEP00000025945	Aldedh domain-containing protein.	Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.	0.410
ENSFHEP00000013747	aass	ENSFHEP00000013747	ENSFHEP00000018619	Aldedh domain-containing protein.	Aminoadipate-semialdehyde synthase.	0.670
ENSFHEP00000013747	aldh1l2	ENSFHEP00000013747	ENSFHEP00000013765	Aldedh domain-containing protein.	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.	0.935
ENSFHEP00000013747	crym	ENSFHEP00000013747	ENSFHEP00000005643	Aldedh domain-containing protein.	Crystallin, mu.	0.562
ENSFHEP00000013747	dhfr	ENSFHEP00000013747	ENSFHEP00000000250	Aldedh domain-containing protein.	Dihydrofolate reductase.	0.942
ENSFHEP00000013747	mthfd1	ENSFHEP00000013747	ENSFHEP00000015673	Aldedh domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.	0.923