(93 nodes) Myosin phosphatase activity network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	LOC105940351	Slingshot protein phosphatase 2a. (1279 aa)
	dusp28	Dual specificity phosphatase 28. (150 aa)
	LOC105929392	Protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative). (447 aa)
	dusp12	Dual specificity phosphatase 12. (303 aa)
	LOC105935842	Protein phosphatase; Belongs to the PP2C family. (297 aa)
	ctdnep1	CTD nuclear envelope phosphatase 1b. (226 aa)
	ENSFHEP00000001331	Coilin_N domain-containing protein. (117 aa)
	ENSFHEP00000001965	TYR_PHOSPHATASE_2 domain-containing protein. (168 aa)
	cdc14a	Cell division cycle 14Ab. (542 aa)
	LOC105932302	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (366 aa)
	PPEF2	Serine/threonine-protein phosphatase with EF-hands. (684 aa)
	LOC105937261	Serine/threonine-protein phosphatase with EF-hands. (712 aa)
	ssu72	SSU72 homolog, RNA polymerase II CTD phosphatase. (194 aa)
	FNDC10	Fibronectin type III domain containing 10. (218 aa)
	pptc7	Protein phosphatase; Belongs to the PP2C family. (297 aa)
	LOC105932774	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (333 aa)
	LOC105932178	Si:dkey-175m17.7. (862 aa)
	LOC105932865	PPM-type phosphatase domain-containing protein. (1674 aa)
	LOC105925933	Serine/threonine-protein phosphatase. (305 aa)
	LOC105918889	Protein phosphatase, Mg2+/Mn2+ dependent, 1Bb. (464 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (301 aa)
	dusp22	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (195 aa)
	DUPD1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (212 aa)
	ppm1a	Protein phosphatase, Mg2+/Mn2+ dependent, 1Aa. (386 aa)
	LOC105921298	Si:ch211-149b19.3. (317 aa)
	LOC105936983	Si:ch211-223p8.8; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (249 aa)
	LOC105916101	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (181 aa)
	LOC105921936	Serine/threonine-protein phosphatase. (309 aa)
	ppm1g	Protein phosphatase, Mg2+/Mn2+ dependent, 1G. (561 aa)
	ppef1	Serine/threonine-protein phosphatase with EF-hands. (702 aa)
	LOC105928226	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (201 aa)
	DUSP13	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (182 aa)
	ENSFHEP00000010072	Tyrosine-protein phosphatase domain-containing protein. (253 aa)
	dusp13	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (186 aa)
	LOC105930846	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2. (261 aa)
	ublcp1	Ubiquitin-like domain containing CTD phosphatase 1. (318 aa)
	ctdspl	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (273 aa)
	rpap2	RNA polymerase II associated protein 2. (629 aa)
	ENSFHEP00000013308	Dual specificity phosphatase 22b. (143 aa)
	LOC105935266	PH domain and leucine rich repeat protein phosphatase 1. (1757 aa)
	ssh1	Slingshot protein phosphatase 1a. (893 aa)
	LOC105929196	Serine/threonine-protein phosphatase. (501 aa)
	ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1. (1031 aa)
	CTDSP1	CTD small phosphatase 1. (260 aa)
	cpped1	Calcineurin-like phosphoesterase domain containing 1. (383 aa)
	LOC105928074	Protein phosphatase, Mg2+/Mn2+ dependent, 1J. (498 aa)
	ppm1k	Protein phosphatase, Mg2+/Mn2+ dependent, 1K. (383 aa)
	ENSFHEP00000016255	Si:ch1073-184j22.2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa)
	LOC105931356	Uncharacterized protein. (553 aa)
	LOC105920955	Serine/threonine-protein phosphatase. (309 aa)
	ppm1b	Protein phosphatase, Mg2+/Mn2+ dependent, 1Ba. (402 aa)
	LOC105925621	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (388 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC105919735	Dual specificity protein phosphatase 22. (201 aa)
	dusp2	Dual specificity phosphatase 2. (315 aa)
	dusp10	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	ppp4c	Serine/threonine-protein phosphatase. (311 aa)
	ENSFHEP00000022973	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (201 aa)
	cdkn3	Cyclin-dependent kinase inhibitor 3. (214 aa)
	LOC105917881	Slingshot protein phosphatase 2b. (1194 aa)
	ppp1cc	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (361 aa)
	ENSFHEP00000025002	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1. (120 aa)
	LOC105933824	Protein phosphatase 1H. (528 aa)
	LOC105936997	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (196 aa)
	LOC105936719	Si:dkey-24f15.2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (237 aa)
	LOC105931113	Serine/threonine-protein phosphatase. (511 aa)
	dusp1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (373 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (224 aa)
	ENSFHEP00000026946	Uncharacterized protein. (72 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (392 aa)
	LOC105928245	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
	dusp4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	LOC110366625	Integrin-linked kinase-associated serine/threonine phosphatase. (124 aa)
	dusp5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (452 aa)
	LOC105915301	Slingshot protein phosphatase 1b. (663 aa)
	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2. (1340 aa)
	ENSFHEP00000029309	Dual specificity phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (181 aa)
	ppm1h	Protein phosphatase, Mg2+/Mn2+ dependent, 1H. (514 aa)
	dusp7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	ENSFHEP00000030564	Uncharacterized protein. (75 aa)
	LOC105936564	Protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative). (436 aa)
	ppm1l	PPM-type phosphatase domain-containing protein. (371 aa)
	DUSP26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa)
	LOC105930301	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b. (285 aa)
	LOC105935930	Protein phosphatase, Mg2+/Mn2+ dependent, 1La. (363 aa)
	iqub	IQ and ubiquitin domain-containing-like protein. (735 aa)
	LOC105926811	Dual specificity protein phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (182 aa)
	ppm1e	Protein phosphatase, Mg2+/Mn2+ dependent, 1E. (615 aa)
	ppp5c	Serine/threonine-protein phosphatase. (479 aa)
	PPP6C	Serine/threonine-protein phosphatase. (347 aa)
	LOC105925566	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	LOC105915415	Serine/threonine-protein phosphatase. (508 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000001331	ppp4c	ENSFHEP00000001331	ENSFHEP00000021916	Coilin_N domain-containing protein.	Serine/threonine-protein phosphatase.	0.503
ENSFHEP00000001965	LOC105931356	ENSFHEP00000001965	ENSFHEP00000016638	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.911
ENSFHEP00000001965	cdc14a	ENSFHEP00000001965	ENSFHEP00000001980	TYR_PHOSPHATASE_2 domain-containing protein.	Cell division cycle 14Ab.	0.488
ENSFHEP00000013308	LOC105928245	ENSFHEP00000013308	ENSFHEP00000027708	Dual specificity phosphatase 22b.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.445
ENSFHEP00000026946	ENSFHEP00000030564	ENSFHEP00000026946	ENSFHEP00000030564	Uncharacterized protein.	Uncharacterized protein.	0.506
ENSFHEP00000026946	FNDC10	ENSFHEP00000026946	ENSFHEP00000003972	Uncharacterized protein.	Fibronectin type III domain containing 10.	0.680
ENSFHEP00000026946	LOC105915301	ENSFHEP00000026946	ENSFHEP00000028960	Uncharacterized protein.	Slingshot protein phosphatase 1b.	0.570
ENSFHEP00000026946	LOC105917881	ENSFHEP00000026946	ENSFHEP00000023464	Uncharacterized protein.	Slingshot protein phosphatase 2b.	0.570
ENSFHEP00000026946	LOC105940351	ENSFHEP00000026946	ENSFHEP00000000356	Uncharacterized protein.	Slingshot protein phosphatase 2a.	0.570
ENSFHEP00000026946	ssh1	ENSFHEP00000026946	ENSFHEP00000013914	Uncharacterized protein.	Slingshot protein phosphatase 1a.	0.570
ENSFHEP00000026946	ssu72	ENSFHEP00000026946	ENSFHEP00000003951	Uncharacterized protein.	SSU72 homolog, RNA polymerase II CTD phosphatase.	0.680
ENSFHEP00000030564	ENSFHEP00000026946	ENSFHEP00000030564	ENSFHEP00000026946	Uncharacterized protein.	Uncharacterized protein.	0.506
ENSFHEP00000030564	FNDC10	ENSFHEP00000030564	ENSFHEP00000003972	Uncharacterized protein.	Fibronectin type III domain containing 10.	0.680
ENSFHEP00000030564	LOC105915301	ENSFHEP00000030564	ENSFHEP00000028960	Uncharacterized protein.	Slingshot protein phosphatase 1b.	0.570
ENSFHEP00000030564	LOC105917881	ENSFHEP00000030564	ENSFHEP00000023464	Uncharacterized protein.	Slingshot protein phosphatase 2b.	0.570
ENSFHEP00000030564	LOC105940351	ENSFHEP00000030564	ENSFHEP00000000356	Uncharacterized protein.	Slingshot protein phosphatase 2a.	0.570
ENSFHEP00000030564	PPP3CA	ENSFHEP00000030564	ENSFHEP00000026933	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.545
ENSFHEP00000030564	dusp1	ENSFHEP00000030564	ENSFHEP00000026375	Uncharacterized protein.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.434
ENSFHEP00000030564	ppp4c	ENSFHEP00000030564	ENSFHEP00000021916	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.449
ENSFHEP00000030564	ssh1	ENSFHEP00000030564	ENSFHEP00000013914	Uncharacterized protein.	Slingshot protein phosphatase 1a.	0.570