127 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wdr54	WD repeat-containing protein 54. (336 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (545 aa)
	LOC105930009	Notch receptor 1a. (2479 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	ptpn5	Protein tyrosine phosphatase non-receptor type 5. (381 aa)
	LOC105927925	RUN and FYVE domain containing 1. (717 aa)
	pacsin1	Protein kinase C and casein kinase substrate in neurons protein 1. (439 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	ENSFHEP00000026509	Synaptosome associated protein 91b. (224 aa)
	RSPO3	R-spondin 3. (210 aa)
	LOC105939523	Apolipoprotein Eb. (284 aa)
	LOC105931543	Uncharacterized protein. (191 aa)
	LOC105931589	Uncharacterized protein. (191 aa)
	ENSFHEP00000011031	Clusterin; Belongs to the clusterin family. (412 aa)
	bmp2k	BMP2 inducible kinase. (501 aa)
	LOC105936103	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	LOC105930418	RAB5A, member RAS oncogene family, a. (216 aa)
	ENSFHEP00000012835	EF-hand domain-containing protein. (73 aa)
	LOC105919313	Uncharacterized protein. (194 aa)
	lrpap1	Low density lipoprotein receptor-related protein associated protein 1. (347 aa)
	tbc1d5	TBC1 domain family, member 5. (870 aa)
	LOC105919902	Sialidase 3 (membrane sialidase), tandem duplicate 1. (410 aa)
	ENSFHEP00000013022	DAB adaptor protein 1b. (386 aa)
	ankrd13a	Ankyrin repeat domain 13A. (597 aa)
	mkln1	Muskelin 1, intracellular mediator containing kelch motifs. (748 aa)
	ENSFHEP00000013800	Gremlin 1a, DAN family BMP antagonist. (181 aa)
	clu	Clusterin; Belongs to the clusterin family. (460 aa)
	cbll1	Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase. (516 aa)
	ENSFHEP00000014197	SH2 domain-containing protein. (261 aa)
	ankfy1	Ankyrin repeat and FYVE domain containing 1. (920 aa)
	gpc3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (541 aa)
	LOC105931113	Serine/threonine-protein phosphatase. (511 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (224 aa)
	LOC105929196	Serine/threonine-protein phosphatase. (501 aa)
	LOC105938824	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	LOC105931461	Uncharacterized protein. (316 aa)
	LOC105928080	Protein kinase C and casein kinase substrate in neurons 1b. (462 aa)
	LOC105926901	Huntingtin interacting protein 1 related b. (1067 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (630 aa)
	LOC105920339	Clusterin; Belongs to the clusterin family. (464 aa)
	ENSFHEP00000016902	Low density lipoprotein receptor adaptor protein 1a. (221 aa)
	LOC105929045	Galectin. (333 aa)
	LOC105918222	Tumor susceptibility 101a. (416 aa)
	ENSFHEP00000026946	Uncharacterized protein. (72 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (623 aa)
	rufy2	RUN and FYVE domain containing 2. (701 aa)
	LOC105930474	C2 domain-containing protein. (382 aa)
	rab5c	RAB5C, member RAS oncogene family. (220 aa)
	LOC105928170	SCY domain-containing protein. (110 aa)
	LOC105923864	Apolipoprotein Ea. (262 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (153 aa)
	LOC105939972	Uncharacterized protein. (220 aa)
	ankrd13d	Ankyrin repeat domain 13 family, member D. (629 aa)
	ENSFHEP00000030564	Uncharacterized protein. (75 aa)
	LOC105932584	RAB guanine nucleotide exchange factor (GEF) 1, like. (504 aa)
	LOC105936561	RAB4B, member RAS oncogene family. (213 aa)
	btbd9	BTB (POZ) domain containing 9. (636 aa)
	ENSFHEP00000032057	Uncharacterized protein. (959 aa)
	rspo1	R-spondin 1. (215 aa)
	ano6	Anoctamin. (910 aa)
	ENSFHEP00000032510	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (133 aa)
	ENSFHEP00000032605	Uncharacterized protein. (68 aa)
	ENSFHEP00000032624	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (194 aa)
	atxn2	Ataxin 2. (1010 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (650 aa)
	dab2	DAB adaptor protein 2. (769 aa)
	CDC42	Cell division control protein 42. (191 aa)
	LOC105926827	AP2 associated kinase 1a. (1054 aa)
	pick1	Protein interacting with prkca 1. (393 aa)
	ENSFHEP00000033314	ANK_REP_REGION domain-containing protein. (762 aa)
	rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (505 aa)
	LOC105917352	VPS9 domain-containing protein. (969 aa)
	UNC119-2	GMP_PDE_delta domain-containing protein. (124 aa)
	arfgap1	ADP-ribosylation factor GTPase activating protein 1. (442 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	LOC105920855	Uncharacterized protein. (358 aa)
	LOC105915415	Serine/threonine-protein phosphatase. (508 aa)
	ENSFHEP00000018558	Protein kinase domain-containing protein. (516 aa)
	UNC119	Unc-119 homolog b (C. elegans). (204 aa)
	LOC105936474	Vitronectin a. (544 aa)
	ENSFHEP00000018998	ENTH domain-containing protein. (234 aa)
	LOC105939281	Vitronectin b. (361 aa)
	ENSFHEP00000019671	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (184 aa)
	ENSFHEP00000019873	GMP_PDE_delta domain-containing protein. (198 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (464 aa)
	fmr1	Fragile X mental retardation 1. (604 aa)
	LOC105926653	Protein kinase C and casein kinase substrate in neurons protein 3. (387 aa)
	syt11	Synaptotagmin XIb. (463 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
	LOC105935812	AP2 associated kinase 1b. (1065 aa)
	cln3	Battenin. (439 aa)
	hip1	Huntingtin interacting protein 1. (1047 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (218 aa)
	LOC105915549	Si:ch211-200p22.4. (583 aa)
	pacsin2	Protein kinase C and casein kinase substrate in neurons protein 2. (507 aa)
	ENSFHEP00000000267	DAB adaptor protein 1a. (540 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (674 aa)
	ankrd13b	Ankyrin repeat domain 13B. (518 aa)
	ahi1	Abelson helper integration site 1. (1202 aa)
	LOC105935780	RAB5B, member RAS oncogene family. (216 aa)
	LOC105940217	Dickkopf WNT signaling pathway inhibitor 1a. (261 aa)
	LOC105934100	Cell division control protein 42. (191 aa)
	ENSFHEP00000002273	PDZ domain-containing protein. (156 aa)
	LOC105932928	Galectin. (373 aa)
	lrsam1	Leucine rich repeat and sterile alpha motif containing 1. (734 aa)
	LOC105928568	Cell division control protein 42. (191 aa)
	scyl2	SCY1 like pseudokinase 2. (915 aa)
	LOC105919566	Gsg1-like. (255 aa)
	picalm	Phosphatidylinositol binding clathrin assembly protein b. (681 aa)
	LOC105932815	Si:ch211-51c14.1. (388 aa)
	GSG1	Uncharacterized protein. (366 aa)
	ston1	Stonin-1; May be involved in the endocytic machinery. (709 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	DGKQ	Diacylglycerol kinase. (783 aa)
	LOC105935574	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (525 aa)
	syt4	Synaptotagmin IV. (471 aa)
	ENSFHEP00000007001	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (253 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1040 aa)
	LOC105915423	Protein kinase C and casein kinase substrate in neurons 3. (418 aa)
	ENSFHEP00000008239	ENTH domain-containing protein. (151 aa)
	tsc2	TSC complex subunit 2. (1700 aa)
	LOC110366958	Zgc:123278. (186 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC105920636	Uncharacterized protein. (362 aa)
	ppp3r1	Uncharacterized protein. (170 aa)
	cd63	Tetraspanin. (240 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSFHEP00000002273	ENSFHEP00000032957	ENSFHEP00000002273	Cell division control protein 42.	PDZ domain-containing protein.	0.489
CDC42	ENSFHEP00000032057	ENSFHEP00000032957	ENSFHEP00000032057	Cell division control protein 42.	Uncharacterized protein.	0.489
CDC42	LOC105920636	ENSFHEP00000032957	ENSFHEP00000008931	Cell division control protein 42.	Uncharacterized protein.	0.489
CDC42	LOC105931543	ENSFHEP00000032957	ENSFHEP00000011007	Cell division control protein 42.	Uncharacterized protein.	0.892
CDC42	LOC105931589	ENSFHEP00000032957	ENSFHEP00000011025	Cell division control protein 42.	Uncharacterized protein.	0.897
CDC42	LOC105934100	ENSFHEP00000032957	ENSFHEP00000001271	Cell division control protein 42.	Cell division control protein 42.	0.897
CDC42	LOC105935574	ENSFHEP00000032957	ENSFHEP00000006341	Cell division control protein 42.	Membrane associated guanylate kinase, WW and PDZ domain containing 2b.	0.489
CDC42	ankfy1	ENSFHEP00000032957	ENSFHEP00000014228	Cell division control protein 42.	Ankyrin repeat and FYVE domain containing 1.	0.614
CDC42	arfgap1	ENSFHEP00000032957	ENSFHEP00000034224	Cell division control protein 42.	ADP-ribosylation factor GTPase activating protein 1.	0.429
CDC42	cav1	ENSFHEP00000032957	ENSFHEP00000008883	Cell division control protein 42.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.448
CDC42	tsc2	ENSFHEP00000032957	ENSFHEP00000008712	Cell division control protein 42.	TSC complex subunit 2.	0.548
ENSFHEP00000000267	ENSFHEP00000008239	ENSFHEP00000000267	ENSFHEP00000008239	DAB adaptor protein 1a.	ENTH domain-containing protein.	0.631
ENSFHEP00000000267	ENSFHEP00000016902	ENSFHEP00000000267	ENSFHEP00000016902	DAB adaptor protein 1a.	Low density lipoprotein receptor adaptor protein 1a.	0.698
ENSFHEP00000000267	ENSFHEP00000018998	ENSFHEP00000000267	ENSFHEP00000018998	DAB adaptor protein 1a.	ENTH domain-containing protein.	0.631
ENSFHEP00000000267	ENSFHEP00000026509	ENSFHEP00000000267	ENSFHEP00000026509	DAB adaptor protein 1a.	Synaptosome associated protein 91b.	0.631
ENSFHEP00000000267	LOC105915549	ENSFHEP00000000267	ENSFHEP00000022481	DAB adaptor protein 1a.	Si:ch211-200p22.4.	0.631
ENSFHEP00000000267	LOC105930474	ENSFHEP00000000267	ENSFHEP00000028039	DAB adaptor protein 1a.	C2 domain-containing protein.	0.582
ENSFHEP00000000267	LOC105940217	ENSFHEP00000000267	ENSFHEP00000001212	DAB adaptor protein 1a.	Dickkopf WNT signaling pathway inhibitor 1a.	0.482
ENSFHEP00000000267	appl1	ENSFHEP00000000267	ENSFHEP00000032899	DAB adaptor protein 1a.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.474
ENSFHEP00000000267	appl2	ENSFHEP00000000267	ENSFHEP00000021452	DAB adaptor protein 1a.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.474