STRINGSTRING
klhl22 klhl22 fnip1 fnip1 LOC105925715 LOC105925715 LOC105929493 LOC105929493 bmt2 bmt2 flcn flcn gsk3b gsk3b ENSFHEP00000031995 ENSFHEP00000031995 ENSFHEP00000032812 ENSFHEP00000032812 mapkapk5 mapkapk5 ENSFHEP00000032875 ENSFHEP00000032875 gba gba LOC105924112 LOC105924112 CASTOR1 CASTOR1 minar1 minar1 rnf152 rnf152 tmem127 tmem127 rptor rptor lamtor2 lamtor2 wac wac nprl3 nprl3 stk11 stk11 ENSFHEP00000001710 ENSFHEP00000001710 prkaa1 prkaa1 deptor deptor wdr24 wdr24 LOC105938731 LOC105938731 ENSFHEP00000034479 ENSFHEP00000034479 ENSFHEP00000034851 ENSFHEP00000034851 lamtor5 lamtor5 akt1s1 akt1s1 GPR137B GPR137B depdc5 depdc5 LOC105932864 LOC105932864 DGKQ DGKQ MINAR1 MINAR1 ENSFHEP00000006808 ENSFHEP00000006808 fbxo9 fbxo9 LOC105919479 LOC105919479 ENSFHEP00000007615 ENSFHEP00000007615 LOC105919467 LOC105919467 cunh12orf66 cunh12orf66 mios mios tsc2 tsc2 sh3bp4 sh3bp4 tti1 tti1 ENSFHEP00000008829 ENSFHEP00000008829 gsk3a gsk3a ift172 ift172 gas6 gas6 lars1 lars1 LOC105925901 LOC105925901 ENSFHEP00000009643 ENSFHEP00000009643 lamtor4 lamtor4 ddit4 ddit4 ENSFHEP00000011014 ENSFHEP00000011014 LOC105917024 LOC105917024 LOC105927446 LOC105927446 lamtor3 lamtor3 sec13 sec13 tmem130 tmem130 rragc rragc seh1l seh1l ENSFHEP00000017385 ENSFHEP00000017385 ENSFHEP00000017412 ENSFHEP00000017412 nprl2 nprl2 ubr2 ubr2 LOC105930296 LOC105930296 golph3 golph3 ENSFHEP00000020833 ENSFHEP00000020833 castor2 castor2 sesn1 sesn1 prkaa2 prkaa2 slc38a9 slc38a9 LOC105927798 LOC105927798 LOC105919602 LOC105919602 fam83d fam83d lamtor1 lamtor1 itfg2 itfg2 zmpste24 zmpste24 clec16a clec16a LOC105939748 LOC105939748 kptn kptn ENSFHEP00000024003 ENSFHEP00000024003 LOC105916159 LOC105916159 wdr59 wdr59 sirt1 sirt1 LOC105925555 LOC105925555 LOC105920118 LOC105920118 RELN RELN rictor rictor
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
klhl22Kelch-like family member 22. (640 aa)
fnip1Folliculin interacting protein 1. (1223 aa)
LOC105925715Si:zfos-80g12.1. (371 aa)
LOC105929493CBM21 domain-containing protein. (1236 aa)
bmt2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (388 aa)
flcnFolliculin. (564 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (425 aa)
ENSFHEP00000031995Uncharacterized protein. (83 aa)
ENSFHEP00000032812Uncharacterized protein. (83 aa)
mapkapk5Protein kinase domain-containing protein. (440 aa)
ENSFHEP00000032875E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (395 aa)
gbaGlucosylceramidase. (607 aa)
LOC105924112Uncharacterized protein. (185 aa)
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1. (327 aa)
minar1UPF0258 protein. (802 aa)
rnf152Ring finger protein 152. (173 aa)
tmem127Transmembrane protein 127. (237 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1250 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (165 aa)
wacWW domain containing adaptor with coiled-coil a. (541 aa)
nprl3Nitrogen permease regulator 3-like protein. (599 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
ENSFHEP00000001710DEP domain-containing protein. (103 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
deptorDEP domain containing MTOR-interacting protein. (404 aa)
wdr24WD repeat domain 24. (706 aa)
LOC105938731Uncharacterized protein. (223 aa)
ENSFHEP00000034479Uncharacterized protein. (67 aa)
ENSFHEP00000034851TAN domain-containing protein. (173 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (94 aa)
akt1s1AKT1 substrate 1 (proline-rich). (353 aa)
GPR137BG protein-coupled receptor 137B. (386 aa)
depdc5DEP domain containing 5. (883 aa)
LOC105932864TBC1 domain family, member 7. (294 aa)
DGKQDiacylglycerol kinase. (783 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (813 aa)
ENSFHEP00000006808Uncharacterized protein. (159 aa)
fbxo9F-box only protein 9. (426 aa)
LOC105919479G protein-coupled receptor 137. (378 aa)
ENSFHEP00000007615Uncharacterized protein. (101 aa)
LOC105919467TSC complex subunit 1. (1034 aa)
cunh12orf66Si:ch211-125a15.1. (450 aa)
miosMissing oocyte, meiosis regulator, homolog (Drosophila). (855 aa)
tsc2TSC complex subunit 2. (1700 aa)
sh3bp4SH3-domain binding protein 4. (965 aa)
tti1TELO2 interacting protein 1. (1103 aa)
ENSFHEP00000008829Uncharacterized protein. (252 aa)
gsk3aGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
ift172Intraflagellar transport 172. (1747 aa)
gas6Uncharacterized protein. (650 aa)
lars1Leucyl-tRNA synthetase b; Belongs to the class-I aminoacyl-tRNA synthetase family. (1068 aa)
LOC1059259015-hydroxytryptamine (serotonin) receptor 6; Belongs to the G-protein coupled receptor 1 family. (451 aa)
ENSFHEP00000009643E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (384 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (162 aa)
ddit4DNA-damage-inducible transcript 4. (225 aa)
ENSFHEP00000011014Golgi phosphoprotein 3. (100 aa)
LOC105917024SH3-domain binding protein 4a. (960 aa)
LOC105927446TSC complex subunit 1b. (1254 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
tmem130Transmembrane protein 130. (335 aa)
rragcRas-related GTP binding Ca. (262 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (383 aa)
ENSFHEP00000017385Uncharacterized protein. (57 aa)
ENSFHEP00000017412Uncharacterized protein. (55 aa)
nprl2NPR2 like, GATOR1 complex subunit. (274 aa)
ubr2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1679 aa)
LOC105930296WW domain-containing protein. (529 aa)
golph3Si:dkey-27b3.2. (294 aa)
ENSFHEP00000020833Uncharacterized protein. (136 aa)
castor2Cytosolic arginine sensor for mTORC1 subunit 2. (290 aa)
sesn1Sestrin 1. (548 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
slc38a9Solute carrier family 38 member 9. (558 aa)
LOC105927798Ras-related GTP binding A. (315 aa)
LOC105919602Si:dkeyp-97e7.9. (313 aa)
fam83dFamily with sequence similarity 83 member D. (541 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
itfg2Integrin alpha FG-GAP repeat containing 2. (433 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (433 aa)
clec16aC-type lectin domain containing 16A. (935 aa)
LOC105939748Zgc:100846. (441 aa)
kptnKaptin (actin binding protein). (442 aa)
ENSFHEP00000024003Protein kinase domain-containing protein. (146 aa)
LOC105916159G protein-coupled receptor 137c. (449 aa)
wdr59WD repeat domain 59. (941 aa)
sirt1Sirtuin 1. (719 aa)
LOC105925555Sestrin 2. (558 aa)
LOC105920118Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (436 aa)
RELNReelin. (3373 aa)
rictorRPTOR independent companion of MTOR, complex 2 a. (1659 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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