(9 nodes) Nucleotide-excision repair, DNA incision network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ercc1	Excision repair cross-complementation group 1. (366 aa)
	bivm	Basic, immunoglobulin-like variable motif containing. (497 aa)
	ercc4	Excision repair cross-complementation group 4. (897 aa)
	ercc5	Excision repair cross-complementation group 5. (1094 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	nthl1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (346 aa)
	ercc2	TFIIH basal transcription factor complex helicase XPD subunit. (795 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	ogg1	8-oxoguanine DNA glycosylase. (393 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bivm	ercc1	ENSFHEP00000009024	ENSFHEP00000007331	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 1.	0.890
bivm	ercc2	ENSFHEP00000009024	ENSFHEP00000022071	Basic, immunoglobulin-like variable motif containing.	TFIIH basal transcription factor complex helicase XPD subunit.	0.966
bivm	ercc3	ENSFHEP00000009024	ENSFHEP00000023902	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 3.	0.975
bivm	ercc4	ENSFHEP00000009024	ENSFHEP00000015698	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 4.	0.904
bivm	ercc5	ENSFHEP00000009024	ENSFHEP00000030245	Basic, immunoglobulin-like variable motif containing.	Excision repair cross-complementation group 5.	0.871
bivm	nthl1	ENSFHEP00000009024	ENSFHEP00000026767	Basic, immunoglobulin-like variable motif containing.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.674
bivm	ogg1	ENSFHEP00000009024	ENSFHEP00000002753	Basic, immunoglobulin-like variable motif containing.	8-oxoguanine DNA glycosylase.	0.584
bivm	xpa	ENSFHEP00000009024	ENSFHEP00000029056	Basic, immunoglobulin-like variable motif containing.	Xeroderma pigmentosum, complementation group A.	0.845
ercc1	bivm	ENSFHEP00000007331	ENSFHEP00000009024	Excision repair cross-complementation group 1.	Basic, immunoglobulin-like variable motif containing.	0.890
ercc1	ercc2	ENSFHEP00000007331	ENSFHEP00000022071	Excision repair cross-complementation group 1.	TFIIH basal transcription factor complex helicase XPD subunit.	0.873
ercc1	ercc3	ENSFHEP00000007331	ENSFHEP00000023902	Excision repair cross-complementation group 1.	Excision repair cross-complementation group 3.	0.890
ercc1	ercc4	ENSFHEP00000007331	ENSFHEP00000015698	Excision repair cross-complementation group 1.	Excision repair cross-complementation group 4.	0.999
ercc1	ercc5	ENSFHEP00000007331	ENSFHEP00000030245	Excision repair cross-complementation group 1.	Excision repair cross-complementation group 5.	0.890
ercc1	nthl1	ENSFHEP00000007331	ENSFHEP00000026767	Excision repair cross-complementation group 1.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.636
ercc1	ogg1	ENSFHEP00000007331	ENSFHEP00000002753	Excision repair cross-complementation group 1.	8-oxoguanine DNA glycosylase.	0.624
ercc1	xpa	ENSFHEP00000007331	ENSFHEP00000029056	Excision repair cross-complementation group 1.	Xeroderma pigmentosum, complementation group A.	0.991
ercc2	bivm	ENSFHEP00000022071	ENSFHEP00000009024	TFIIH basal transcription factor complex helicase XPD subunit.	Basic, immunoglobulin-like variable motif containing.	0.966
ercc2	ercc1	ENSFHEP00000022071	ENSFHEP00000007331	TFIIH basal transcription factor complex helicase XPD subunit.	Excision repair cross-complementation group 1.	0.873
ercc2	ercc3	ENSFHEP00000022071	ENSFHEP00000023902	TFIIH basal transcription factor complex helicase XPD subunit.	Excision repair cross-complementation group 3.	0.999
ercc2	ercc4	ENSFHEP00000022071	ENSFHEP00000015698	TFIIH basal transcription factor complex helicase XPD subunit.	Excision repair cross-complementation group 4.	0.885