(11 nodes) Histone arginine methylation network (Fundulus heteroclitus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	carm1	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (590 aa)
	LOC105936652	PR domain containing 1a, with ZNF domain. (837 aa)
	LOC105925854	Nuclear receptor subfamily 1, group H, member 5. (494 aa)
	prdm14	PR domain containing 14. (587 aa)
	LOC105917391	PR domain containing 1b, with ZNF domain. (623 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (489 aa)
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (652 aa)
	mettl23	Methyltransferase like 23. (231 aa)
	prmt6	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (351 aa)
	prmt7	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (687 aa)
	LOC105929577	Uncharacterized protein. (787 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105917391	prmt5	ENSFHEP00000032993	ENSFHEP00000015583	PR domain containing 1b, with ZNF domain.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.648
LOC105925854	carm1	ENSFHEP00000028266	ENSFHEP00000021903	Nuclear receptor subfamily 1, group H, member 5.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.623
LOC105929577	prmt5	ENSFHEP00000020718	ENSFHEP00000015583	Uncharacterized protein.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.634
LOC105936652	prmt5	ENSFHEP00000026187	ENSFHEP00000015583	PR domain containing 1a, with ZNF domain.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.437
carm1	LOC105925854	ENSFHEP00000021903	ENSFHEP00000028266	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor subfamily 1, group H, member 5.	0.623
carm1	nr1h4	ENSFHEP00000021903	ENSFHEP00000007391	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor subfamily 1, group H, member 4.	0.623
carm1	prdm14	ENSFHEP00000021903	ENSFHEP00000031668	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	PR domain containing 14.	0.418
carm1	prmt5	ENSFHEP00000021903	ENSFHEP00000015583	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.693
carm1	prmt6	ENSFHEP00000021903	ENSFHEP00000018702	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.662
mettl23	prmt7	ENSFHEP00000018389	ENSFHEP00000018926	Methyltransferase like 23.	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...]	0.471
nr1h4	carm1	ENSFHEP00000007391	ENSFHEP00000021903	Nuclear receptor subfamily 1, group H, member 4.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.623
prdm14	carm1	ENSFHEP00000031668	ENSFHEP00000021903	PR domain containing 14.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.418
prmt5	LOC105917391	ENSFHEP00000015583	ENSFHEP00000032993	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	PR domain containing 1b, with ZNF domain.	0.648
prmt5	LOC105929577	ENSFHEP00000015583	ENSFHEP00000020718	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	Uncharacterized protein.	0.634
prmt5	LOC105936652	ENSFHEP00000015583	ENSFHEP00000026187	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	PR domain containing 1a, with ZNF domain.	0.437
prmt5	carm1	ENSFHEP00000015583	ENSFHEP00000021903	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.693
prmt5	prmt6	ENSFHEP00000015583	ENSFHEP00000018702	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.731
prmt5	prmt7	ENSFHEP00000015583	ENSFHEP00000018926	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...]	0.865
prmt6	carm1	ENSFHEP00000018702	ENSFHEP00000021903	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.662
prmt6	prmt5	ENSFHEP00000018702	ENSFHEP00000015583	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.731