69 items (Fundulus heteroclitus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSFHEP00000017354	Mitochondrial ribosomal protein S27. (178 aa)
	YTHDF1	YTH N6-methyladenosine RNA binding protein 1. (618 aa)
	eri1	Exoribonuclease 1. (350 aa)
	LOC105931874	Zgc:109965. (550 aa)
	sec61g	SEC61 translocon gamma subunit. (68 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (652 aa)
	gcn1	GCN1 activator of EIF2AK4. (2578 aa)
	LOC105920221	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a. (868 aa)
	OLA1	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (398 aa)
	ncln	Nicalin. (541 aa)
	SEC61A1	Plug_translocon domain-containing protein. (476 aa)
	dnajc2	DnaJ (Hsp40) homolog, subfamily C, member 2. (617 aa)
	pym1	PYM homolog 1, exon junction complex associated factor. (214 aa)
	letmd1	LETM1 domain containing 1. (361 aa)
	ENSFHEP00000005850	Eukaryotic translation initiation factor 5A. (159 aa)
	LOC105927183	Protein transport protein Sec61 subunit alpha. (476 aa)
	LOC105931004	Cytoplasmic polyadenylation element binding protein 4a. (740 aa)
	LOC105936744	Si:dkey-82o10.4. (280 aa)
	eif2a	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (704 aa)
	LOC105939046	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (395 aa)
	letm1	Leucine zipper-EF-hand containing transmembrane protein 1. (756 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2495 aa)
	gtpbp6	GTP binding protein 6 (putative). (518 aa)
	wdr31	WD repeat domain 31. (253 aa)
	rack1	Receptor for activated C kinase 1. (317 aa)
	LOC105931457	Uncharacterized protein. (830 aa)
	tmco1	Transmembrane and coiled-coil domains 1. (235 aa)
	mtif3	Mitochondrial translational initiation factor 3. (281 aa)
	tmem147	Transmembrane protein 147. (225 aa)
	LOC105931477	Nodal modulator. (1221 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1434 aa)
	guf1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (673 aa)
	maip1	Matrix AAA peptidase interacting protein 1. (230 aa)
	ttc5	Tetratricopeptide repeat domain 5. (441 aa)
	EFL1	Elongation factor like GTPase 1. (1108 aa)
	eif6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (246 aa)
	abcf1	ATP-binding cassette, sub-family F (GCN20), member 1. (761 aa)
	LOC105935276	YTH N(6)-methyladenosine RNA binding protein 1. (613 aa)
	letm2	Leucine zipper-EF-hand containing transmembrane protein 2. (516 aa)
	ENSFHEP00000033798	Growth arrest and DNA-damage-inducible, gamma interacting protein 1. (207 aa)
	tsr2	Uncharacterized protein. (205 aa)
	LOC105935365	Eukaryotic translation initiation factor 5A. (162 aa)
	oxa1l	OXA1L mitochondrial inner membrane protein. (488 aa)
	rpn2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (659 aa)
	LOC105925262	SERPINE1 mRNA binding protein 1b. (404 aa)
	cpeb1	Cytoplasmic polyadenylation element binding protein 1b. (577 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
	srp68	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (559 aa)
	cpeb2	Cytoplasmic polyadenylation element binding protein 2. (756 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1659 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (698 aa)
	LOC105916108	Translational activator of mitochondrially encoded cytochrome c oxidase I. (287 aa)
	eif3k	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (220 aa)
	znf598	Zinc finger protein 598. (1020 aa)
	c1qbp	Complement component 1, q subcomponent binding protein. (286 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	EIF5A	Eukaryotic translation initiation factor 5A. (145 aa)
	sbds	SBDS ribosome maturation factor. (249 aa)
	spcs1	Signal peptidase complex subunit 1. (102 aa)
	ighmbp2	Immunoglobulin mu DNA binding protein 2. (978 aa)
	cpeb3	Cytoplasmic polyadenylation element binding protein 3. (686 aa)
	prmt3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (522 aa)
	ENSFHEP00000019799	Ubiquitin-like domain-containing protein. (163 aa)
	ccdc47	Coiled-coil domain containing 47. (489 aa)
	zc3h12a	Zinc finger CCCH-type containing 12A. (618 aa)
	impact	Impact RWD domain protein. (339 aa)
	LOC105932454	SERPINE1 mRNA binding protein 1a. (428 aa)
	LOC105921986	Si:dkey-206d17.12. (588 aa)
	ltv1	LTV1 ribosome biogenesis factor. (473 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPEB4	cpeb1	ENSFHEP00000027302	ENSFHEP00000029843	Cytoplasmic polyadenylation element binding protein 4.	Cytoplasmic polyadenylation element binding protein 1b.	0.802
CPEB4	cpeb2	ENSFHEP00000027302	ENSFHEP00000028771	Cytoplasmic polyadenylation element binding protein 4.	Cytoplasmic polyadenylation element binding protein 2.	0.810
EFL1	EIF5A	ENSFHEP00000016013	ENSFHEP00000021827	Elongation factor like GTPase 1.	Eukaryotic translation initiation factor 5A.	0.868
EFL1	ENSFHEP00000005850	ENSFHEP00000016013	ENSFHEP00000005850	Elongation factor like GTPase 1.	Eukaryotic translation initiation factor 5A.	0.868
EFL1	ENSFHEP00000017354	ENSFHEP00000016013	ENSFHEP00000017354	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S27.	0.451
EFL1	ENSFHEP00000033798	ENSFHEP00000016013	ENSFHEP00000033798	Elongation factor like GTPase 1.	Growth arrest and DNA-damage-inducible, gamma interacting protein 1.	0.420
EFL1	LOC105925262	ENSFHEP00000016013	ENSFHEP00000030480	Elongation factor like GTPase 1.	SERPINE1 mRNA binding protein 1b.	0.644
EFL1	LOC105927183	ENSFHEP00000016013	ENSFHEP00000005878	Elongation factor like GTPase 1.	Protein transport protein Sec61 subunit alpha.	0.814
EFL1	LOC105932454	ENSFHEP00000016013	ENSFHEP00000000434	Elongation factor like GTPase 1.	SERPINE1 mRNA binding protein 1a.	0.644
EFL1	LOC105935365	ENSFHEP00000016013	ENSFHEP00000032194	Elongation factor like GTPase 1.	Eukaryotic translation initiation factor 5A.	0.868
EFL1	LOC105939046	ENSFHEP00000016013	ENSFHEP00000007844	Elongation factor like GTPase 1.	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.	0.440
EFL1	OLA1	ENSFHEP00000016013	ENSFHEP00000004293	Elongation factor like GTPase 1.	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.	0.440
EFL1	SEC61A1	ENSFHEP00000016013	ENSFHEP00000004874	Elongation factor like GTPase 1.	Plug_translocon domain-containing protein.	0.814
EFL1	abcf1	ENSFHEP00000016013	ENSFHEP00000016193	Elongation factor like GTPase 1.	ATP-binding cassette, sub-family F (GCN20), member 1.	0.401
EFL1	eif2s1	ENSFHEP00000016013	ENSFHEP00000022871	Elongation factor like GTPase 1.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.607
EFL1	eif6	ENSFHEP00000016013	ENSFHEP00000016044	Elongation factor like GTPase 1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.873
EFL1	gcn1	ENSFHEP00000016013	ENSFHEP00000003837	Elongation factor like GTPase 1.	GCN1 activator of EIF2AK4.	0.720
EFL1	oxa1l	ENSFHEP00000016013	ENSFHEP00000031446	Elongation factor like GTPase 1.	OXA1L mitochondrial inner membrane protein.	0.585
EFL1	rack1	ENSFHEP00000016013	ENSFHEP00000011700	Elongation factor like GTPase 1.	Receptor for activated C kinase 1.	0.809
EFL1	sbds	ENSFHEP00000016013	ENSFHEP00000018962	Elongation factor like GTPase 1.	SBDS ribosome maturation factor.	0.984