(23 nodes) Brain morphogenesis network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lamc3	Laminin, gamma 3. (1168 aa)
	mkks	McKusick-Kaufman/Bardet-Biedl syndromes chaperonin, putative. (614 aa)
	LOC105926890	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (546 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (323 aa)
	bbs1	Bardet-Biedl syndrome 1. (453 aa)
	LOC105920490	Homeobox domain-containing protein. (170 aa)
	ENSFHEP00000027483	Uncharacterized protein. (146 aa)
	lamc1	Laminin, gamma 1. (1014 aa)
	ctnna1	Catenin (cadherin-associated protein), alpha 1. (907 aa)
	fancd2	FA complementation group D2. (1376 aa)
	znf335	Zinc finger protein 335. (1599 aa)
	nf1	Neurofibromin 1b. (2547 aa)
	slc6a4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (673 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (812 aa)
	gsx2	GS homeobox 2. (239 aa)
	fancc	FA complementation group C. (633 aa)
	ENSFHEP00000014438	BBS1 domain-containing protein. (140 aa)
	ENSFHEP00000014141	Laminin N-terminal domain-containing protein. (251 aa)
	bbs4	Bardet-Biedl syndrome 4. (544 aa)
	crppa	CDP-L-ribitol pyrophosphorylase A. (447 aa)
	ctnna2	Catenin (cadherin-associated protein), alpha 2. (896 aa)
	LOC105924070	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (441 aa)
	LOC105926723	Forkhead box H1. (500 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000014141	ENSFHEP00000027483	ENSFHEP00000014141	ENSFHEP00000027483	Laminin N-terminal domain-containing protein.	Uncharacterized protein.	0.899
ENSFHEP00000014141	lamc1	ENSFHEP00000014141	ENSFHEP00000027450	Laminin N-terminal domain-containing protein.	Laminin, gamma 1.	0.924
ENSFHEP00000014141	lamc3	ENSFHEP00000014141	ENSFHEP00000001282	Laminin N-terminal domain-containing protein.	Laminin, gamma 3.	0.900
ENSFHEP00000014438	bbs1	ENSFHEP00000014438	ENSFHEP00000029422	BBS1 domain-containing protein.	Bardet-Biedl syndrome 1.	0.962
ENSFHEP00000014438	bbs4	ENSFHEP00000014438	ENSFHEP00000013627	BBS1 domain-containing protein.	Bardet-Biedl syndrome 4.	0.988
ENSFHEP00000014438	smo	ENSFHEP00000014438	ENSFHEP00000018258	BBS1 domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.756
ENSFHEP00000027483	ENSFHEP00000014141	ENSFHEP00000027483	ENSFHEP00000014141	Uncharacterized protein.	Laminin N-terminal domain-containing protein.	0.899
ENSFHEP00000027483	lamc1	ENSFHEP00000027483	ENSFHEP00000027450	Uncharacterized protein.	Laminin, gamma 1.	0.927
bbs1	ENSFHEP00000014438	ENSFHEP00000029422	ENSFHEP00000014438	Bardet-Biedl syndrome 1.	BBS1 domain-containing protein.	0.962
bbs1	bbs4	ENSFHEP00000029422	ENSFHEP00000013627	Bardet-Biedl syndrome 1.	Bardet-Biedl syndrome 4.	0.988
bbs1	smo	ENSFHEP00000029422	ENSFHEP00000018258	Bardet-Biedl syndrome 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.756
bbs4	ENSFHEP00000014438	ENSFHEP00000013627	ENSFHEP00000014438	Bardet-Biedl syndrome 4.	BBS1 domain-containing protein.	0.988
bbs4	bbs1	ENSFHEP00000013627	ENSFHEP00000029422	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.988
bbs4	smo	ENSFHEP00000013627	ENSFHEP00000018258	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.715
ctnna1	ctnna2	ENSFHEP00000025516	ENSFHEP00000006767	Catenin (cadherin-associated protein), alpha 1.	Catenin (cadherin-associated protein), alpha 2.	0.943
ctnna2	ctnna1	ENSFHEP00000006767	ENSFHEP00000025516	Catenin (cadherin-associated protein), alpha 2.	Catenin (cadherin-associated protein), alpha 1.	0.943
fancc	fancd2	ENSFHEP00000016144	ENSFHEP00000024652	FA complementation group C.	FA complementation group D2.	0.997
fancd2	fancc	ENSFHEP00000024652	ENSFHEP00000016144	FA complementation group D2.	FA complementation group C.	0.997
lamc1	ENSFHEP00000014141	ENSFHEP00000027450	ENSFHEP00000014141	Laminin, gamma 1.	Laminin N-terminal domain-containing protein.	0.924
lamc1	ENSFHEP00000027483	ENSFHEP00000027450	ENSFHEP00000027483	Laminin, gamma 1.	Uncharacterized protein.	0.927