STRINGSTRING
tirap tirap ENSFHEP00000031404 ENSFHEP00000031404 LOC105919258 LOC105919258 prdx3 prdx3 ENSFHEP00000032510 ENSFHEP00000032510 nkx3-1 nkx3-1 myocd myocd arid5b arid5b LOC105926891 LOC105926891 sav1 sav1 stk36 stk36 fzd4 fzd4 LOC105932356 LOC105932356 rgcc rgcc LOC105929512 LOC105929512 plpp3 plpp3 LOC105937012 LOC105937012 pink1 pink1 ikbkb ikbkb ENSFHEP00000005743 ENSFHEP00000005743 JMY JMY ENSFHEP00000005082 ENSFHEP00000005082 ENSFHEP00000005073 ENSFHEP00000005073 LOC105924010 LOC105924010 trappc9 trappc9 malt1 malt1 cops5 cops5 pprc1 pprc1 traf2 traf2 cth cth ENSFHEP00000006920 ENSFHEP00000006920 ENSFHEP00000007155 ENSFHEP00000007155 ENSFHEP00000007163 ENSFHEP00000007163 abra abra ENSFHEP00000007629 ENSFHEP00000007629 eda eda LOC105934457 LOC105934457 cav1 cav1 card11 card11 LOC105936082 LOC105936082 LOC105925123 LOC105925123 LOC105930993 LOC105930993 ndp ndp ENSFHEP00000009615 ENSFHEP00000009615 nod2 nod2 traf6 traf6 taf12 taf12 adcy8 adcy8 JMY-2 JMY-2 ENSFHEP00000011031 ENSFHEP00000011031 LOC105927502 LOC105927502 mbtps2 mbtps2 ENSFHEP00000012324 ENSFHEP00000012324 dhx33 dhx33 prkcz prkcz LOC105925268 LOC105925268 LOC105921731 LOC105921731 ENSFHEP00000013165 ENSFHEP00000013165 ripk1 ripk1 crtc1 crtc1 ripk4 ripk4 LOC105935238 LOC105935238 srf srf ENSFHEP00000013800 ENSFHEP00000013800 fosl1 fosl1 clu clu ddit3 ddit3 LOC105933743 LOC105933743 LOC105930854 LOC105930854 LOC105925720 LOC105925720 ENSFHEP00000015203 ENSFHEP00000015203 ripk2 ripk2 LOC105933211 LOC105933211 crtc3 crtc3 ENSFHEP00000016845 ENSFHEP00000016845 LOC105920339 LOC105920339 ENSFHEP00000017392 ENSFHEP00000017392 ENSFHEP00000017581 ENSFHEP00000017581 mtpn mtpn ENSFHEP00000017833 ENSFHEP00000017833 LOC105928511 LOC105928511 ENSFHEP00000018037 ENSFHEP00000018037 smo smo ARHGEF2 ARHGEF2 trim37 trim37 ep300 ep300 il1rap il1rap ENSFHEP00000019366 ENSFHEP00000019366 ENSFHEP00000019671 ENSFHEP00000019671 il10 il10 rnf220 rnf220 LOC105938151 LOC105938151 trim62 trim62 ENSFHEP00000020686 ENSFHEP00000020686 LOC105937422 LOC105937422 ENSFHEP00000021564 ENSFHEP00000021564 LOC105917287 LOC105917287 LOC105935791 LOC105935791 LOC105931285 LOC105931285 LOC105938713 LOC105938713 AR AR LOC105915564 LOC105915564 card14 card14 ENSFHEP00000022956 ENSFHEP00000022956 tnfrsf11a tnfrsf11a CYTL1 CYTL1 LOC105938715 LOC105938715 rnf31 rnf31 LOC105936849 LOC105936849 trim32 trim32 LOC105930638 LOC105930638 CHUK CHUK ENSFHEP00000023935 ENSFHEP00000023935 LOC105920957 LOC105920957 ENSFHEP00000024465 ENSFHEP00000024465 LOC105920505 LOC105920505 LOC105932885 LOC105932885 nod1 nod1 rwdd1 rwdd1 RELN RELN vegfa vegfa LOC105934457-2 LOC105934457-2 LOC105931563 LOC105931563 lrp6 lrp6 ENSFHEP00000027841 ENSFHEP00000027841 kdm1a kdm1a ENSFHEP00000028113 ENSFHEP00000028113 ENSFHEP00000028452 ENSFHEP00000028452 lrp5 lrp5 ppargc1b ppargc1b GREM1 GREM1 LOC105923645 LOC105923645 TNFRSF19 TNFRSF19 LOC105925813 LOC105925813 LOC105935995 LOC105935995 LOC105935999 LOC105935999 LOC105919183 LOC105919183 ENSFHEP00000033393 ENSFHEP00000033393 ENSFHEP00000033440 ENSFHEP00000033440 LOC105924502 LOC105924502 psma6 psma6 LOC105919145 LOC105919145 ppargc1a ppargc1a SOX1 SOX1 LOC105933655 LOC105933655 terf2ip terf2ip
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tirapToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (274 aa)
ENSFHEP00000031404Ig-like domain-containing protein. (164 aa)
LOC105919258Interleukin-1 receptor-associated kinase 1. (709 aa)
prdx3Peroxiredoxin 3. (248 aa)
ENSFHEP00000032510PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (133 aa)
nkx3-1NK3 homeobox 1. (187 aa)
myocdSAP domain-containing protein. (951 aa)
arid5bAT-rich interaction domain 5B. (808 aa)
LOC105926891CD40 molecule, TNF receptor superfamily member 5. (308 aa)
sav1Salvador family WW domain containing protein 1. (401 aa)
stk36Serine/threonine kinase 36 (fused homolog, Drosophila). (1064 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
LOC105932356MALT paracaspase 3. (653 aa)
rgccRegulator of cell cycle. (127 aa)
LOC105929512Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1189 aa)
plpp3Phospholipid phosphatase 3. (313 aa)
LOC105937012Component of inhibitor of nuclear factor kappa B kinase complex. (703 aa)
pink1PTEN induced kinase 1. (585 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (743 aa)
ENSFHEP00000005743Ring finger protein 220b. (245 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (864 aa)
ENSFHEP00000005082Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
ENSFHEP00000005073CREB regulated transcription coactivator 1a. (322 aa)
LOC105924010Uncharacterized protein. (323 aa)
trappc9Trafficking protein particle complex 9. (1137 aa)
malt1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (830 aa)
cops5COP9 signalosome subunit 5. (334 aa)
pprc1PPARG related coactivator 1. (1342 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
cthCystathionase (cystathionine gamma-lyase), like. (408 aa)
ENSFHEP00000006920Ig-like domain-containing protein. (237 aa)
ENSFHEP00000007155Protein kinase domain-containing protein. (87 aa)
ENSFHEP00000007163Uncharacterized protein. (75 aa)
abraActin binding Rho activating protein b. (409 aa)
ENSFHEP00000007629RWD domain-containing protein. (323 aa)
edaEctodysplasin A; Belongs to the tumor necrosis factor family. (367 aa)
LOC105934457Uncharacterized protein. (524 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
card11Caspase recruitment domain-containing protein 11. (1152 aa)
LOC105936082Tripartite motif containing 35, putative. (265 aa)
LOC105925123Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (471 aa)
LOC105930993Actin binding Rho activating protein a. (358 aa)
ndpNorrin cystine knot growth factor NDP. (143 aa)
ENSFHEP00000009615DRBM domain-containing protein. (391 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (1000 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (161 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1214 aa)
JMY-2Junction mediating and regulatory protein, p53 cofactor. (891 aa)
ENSFHEP00000011031Clusterin; Belongs to the clusterin family. (412 aa)
LOC105927502SRY-box transcription factor 1a. (344 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (499 aa)
ENSFHEP00000012324G_PROTEIN_RECEP_F2_4 domain-containing protein. (318 aa)
dhx33DEAH (Asp-Glu-Ala-His) box polypeptide 33. (643 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (570 aa)
LOC105925268acidPPc domain-containing protein. (343 aa)
LOC105921731Ig-like domain-containing protein. (329 aa)
ENSFHEP00000013165Ig-like domain-containing protein. (264 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (676 aa)
crtc1CREB regulated transcription coactivator 1b. (607 aa)
ripk4Receptor-interacting serine-threonine kinase 4. (816 aa)
LOC105935238Adenylate cyclase 1b. (941 aa)
srfSerum response factor b. (599 aa)
ENSFHEP00000013800Gremlin 1a, DAN family BMP antagonist. (181 aa)
fosl1FOS-like antigen 1a. (341 aa)
cluClusterin; Belongs to the clusterin family. (460 aa)
ddit3DNA-damage-inducible transcript 3. (313 aa)
LOC105933743Zgc:77151. (885 aa)
LOC105930854E1A binding protein p300 a. (2838 aa)
LOC105925720Tumor necrosis factor ligand superfamily member; Belongs to the tumor necrosis factor family. (237 aa)
ENSFHEP00000015203TNFR-Cys domain-containing protein. (160 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (576 aa)
LOC105933211Proteasome subunit alpha type. (257 aa)
crtc3CREB regulated transcription coactivator 3. (698 aa)
ENSFHEP00000016845Ig-like domain-containing protein. (96 aa)
LOC105920339Clusterin; Belongs to the clusterin family. (464 aa)
ENSFHEP00000017392RRM domain-containing protein. (514 aa)
ENSFHEP00000017581Ig-like domain-containing protein. (237 aa)
mtpnUncharacterized protein. (50 aa)
ENSFHEP00000017833Uncharacterized protein. (372 aa)
LOC105928511Metadherin a. (469 aa)
ENSFHEP00000018037Uncharacterized protein. (252 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (812 aa)
ARHGEF2Rho/rac guanine nucleotide exchange factor (GEF) 2. (829 aa)
trim37Tripartite motif containing 37. (996 aa)
ep300E1A binding protein p300 b. (2738 aa)
il1rapUncharacterized protein. (611 aa)
ENSFHEP00000019366TORC_N domain-containing protein. (80 aa)
ENSFHEP00000019671Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (184 aa)
il10Interleukin 10. (268 aa)
rnf220Ring finger protein 220a. (629 aa)
LOC105938151Interleukin-1. (297 aa)
trim62Tripartite motif containing 62, tandem duplicate 1. (475 aa)
ENSFHEP00000020686DRBM domain-containing protein. (159 aa)
LOC105937422Uncharacterized protein. (258 aa)
ENSFHEP00000021564Ribosomal protein S6 kinase, polypeptide 5. (292 aa)
LOC105917287Junction plakoglobin a. (722 aa)
LOC105935791TNF superfamily member 11; Belongs to the tumor necrosis factor family. (269 aa)
LOC105931285Androgen receptor. (683 aa)
LOC105938713Receptor-interacting serine-threonine kinase 3. (436 aa)
ARAndrogen receptor. (752 aa)
LOC105915564TNF receptor-associated factor. (476 aa)
card14Caspase recruitment domain family, member 14. (779 aa)
ENSFHEP00000022956SRY-box transcription factor 2. (306 aa)
tnfrsf11aTumor necrosis factor receptor superfamily, member 11a, NFKB activator. (561 aa)
CYTL1Cytokine like 1. (146 aa)
LOC105938715RING-type domain-containing protein. (602 aa)
rnf31Ring finger protein 31. (987 aa)
LOC105936849Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (823 aa)
trim32Tripartite motif containing 32. (680 aa)
LOC105930638Proteasome subunit alpha type. (246 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (765 aa)
ENSFHEP00000023935Si:dkey-23i12.7. (176 aa)
LOC105920957Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
ENSFHEP00000024465TORC_N domain-containing protein. (71 aa)
LOC105920505Neurogenin 1. (193 aa)
LOC105932885Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
nod1Nucleotide-binding oligomerization domain containing 1. (941 aa)
rwdd1RWD domain containing 1. (224 aa)
RELNReelin. (3373 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC105934457-2Uncharacterized protein. (404 aa)
LOC105931563Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (529 aa)
lrp6Low density lipoprotein receptor-related protein 6. (784 aa)
ENSFHEP00000027841Uncharacterized protein. (221 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (834 aa)
ENSFHEP00000028113Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (468 aa)
ENSFHEP00000028452Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (398 aa)
lrp5Low density lipoprotein receptor-related protein 5. (1600 aa)
ppargc1bPeroxisome proliferator-activated receptor gamma, coactivator 1 beta. (927 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (153 aa)
LOC105923645Endothelin 1. (218 aa)
TNFRSF19TNF receptor superfamily member 19. (425 aa)
LOC105925813SRY-box transcription factor 3. (300 aa)
LOC105935995Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
LOC105935999RanBP-type and C3HC4-type zinc finger-containing protein 1. (510 aa)
LOC105919183Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (498 aa)
ENSFHEP00000033393Ig-like domain-containing protein. (224 aa)
ENSFHEP00000033440Uncharacterized protein. (140 aa)
LOC105924502Protein kinase domain-containing protein. (279 aa)
psma6Proteasome subunit alpha type. (246 aa)
LOC105919145Tumor necrosis factor b (TNF superfamily, member 2). (278 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1270 aa)
SOX1HMG box domain-containing protein. (354 aa)
LOC105933655TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
terf2ipTelomeric repeat-binding factor 2-interacting protein 1. (698 aa)
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.