(18 nodes) Smooth muscle cell differentiation network (Fundulus heteroclitus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105930469	Mesoderm posterior protein. (255 aa)
	tmem204	Transmembrane protein 204. (215 aa)
	LOC105937351	Myocardin related transcription factor Bb. (903 aa)
	LOC105924010	Uncharacterized protein. (323 aa)
	LOC105921308	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (410 aa)
	ednra	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	srf	Serum response factor b. (599 aa)
	ENSFHEP00000015731	Phosphatase and actin regulator. (157 aa)
	nfatc4	Nuclear factor of activated T cells 4. (897 aa)
	LOC105933509	Myocardin related transcription factor Aa. (1097 aa)
	LOC105929187	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
	LOC105930860	Myocardin related transcription factor Ab. (1285 aa)
	ENSFHEP00000031479	Uncharacterized protein. (82 aa)
	LOC105919250	MBD domain-containing protein. (881 aa)
	tbx3	T-box transcription factor 3a. (764 aa)
	sgcb	Sarcoglycan, beta (dystrophin-associated glycoprotein). (310 aa)
	LOC105930247	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	LOC105933618	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (424 aa)

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000015731	LOC105924010	ENSFHEP00000015731	ENSFHEP00000004618	Phosphatase and actin regulator.	Uncharacterized protein.	0.826
ENSFHEP00000015731	srf	ENSFHEP00000015731	ENSFHEP00000013718	Phosphatase and actin regulator.	Serum response factor b.	0.826
ENSFHEP00000031479	LOC105924010	ENSFHEP00000031479	ENSFHEP00000004618	Uncharacterized protein.	Uncharacterized protein.	0.826
ENSFHEP00000031479	srf	ENSFHEP00000031479	ENSFHEP00000013718	Uncharacterized protein.	Serum response factor b.	0.826
LOC105921308	LOC105929187	ENSFHEP00000006082	ENSFHEP00000030189	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.791
LOC105921308	LOC105930247	ENSFHEP00000006082	ENSFHEP00000032548	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.708
LOC105921308	LOC105933618	ENSFHEP00000006082	ENSFHEP00000034158	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.707
LOC105921308	ednra	ENSFHEP00000006082	ENSFHEP00000006902	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.933
LOC105924010	ENSFHEP00000015731	ENSFHEP00000004618	ENSFHEP00000015731	Uncharacterized protein.	Phosphatase and actin regulator.	0.826
LOC105924010	ENSFHEP00000031479	ENSFHEP00000004618	ENSFHEP00000031479	Uncharacterized protein.	Uncharacterized protein.	0.826
LOC105924010	LOC105930860	ENSFHEP00000004618	ENSFHEP00000031173	Uncharacterized protein.	Myocardin related transcription factor Ab.	0.863
LOC105924010	LOC105933509	ENSFHEP00000004618	ENSFHEP00000023973	Uncharacterized protein.	Myocardin related transcription factor Aa.	0.826
LOC105924010	LOC105937351	ENSFHEP00000004618	ENSFHEP00000001970	Uncharacterized protein.	Myocardin related transcription factor Bb.	0.863
LOC105924010	nfatc4	ENSFHEP00000004618	ENSFHEP00000023571	Uncharacterized protein.	Nuclear factor of activated T cells 4.	0.731
LOC105924010	srf	ENSFHEP00000004618	ENSFHEP00000013718	Uncharacterized protein.	Serum response factor b.	0.933
LOC105929187	LOC105921308	ENSFHEP00000030189	ENSFHEP00000006082	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.791
LOC105929187	LOC105930247	ENSFHEP00000030189	ENSFHEP00000032548	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.953
LOC105929187	LOC105933618	ENSFHEP00000030189	ENSFHEP00000034158	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.953
LOC105929187	ednra	ENSFHEP00000030189	ENSFHEP00000006902	Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.798
LOC105930247	LOC105921308	ENSFHEP00000032548	ENSFHEP00000006082	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.708